ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPre-steady-state kinetic analysis of processive DNA replication including complete characterization an exonuclease-deficient mutantSmita S. Patel, Isaac Wong, and Kenneth A. JohnsonCite this: Biochemistry 1991, 30, 2, 511–525Publication Date (Print):January 15, 1991Publication History Published online1 May 2002Published inissue 15 January 1991https://pubs.acs.org/doi/10.1021/bi00216a029https://doi.org/10.1021/bi00216a029research-articleACS...

In this study of the results anterior interbody cervical-spine fusion for chronic neck pain due to disc degeneration, approximately 73 per cent fifty-five patients evaluated were markedly benefited two seventy-three months after operation. Those with disease localized one or

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kineticsIsaac Wong, Smita S. Patel, and Kenneth A. JohnsonCite this: Biochemistry 1991, 30, 2, 526–537Publication Date (Print):January 15, 1991Publication History Published online1 May 2002Published inissue 15 January 1991https://pubs.acs.org/doi/10.1021/bi00216a030https://doi.org/10.1021/bi00216a030research-articleACS PublicationsRequest reuse...

Rupture of the tibialis posterior (TP) tendon occurs most commonly in adult women. It evolves as an insidious, painful, and progressive flatfoot deformity. Watching for such deformities too many toes including single heel rise test examination will facilitate accurate diagnosis. The treatment rationale should consider site extent disruption, well presence secondary Early help to prevent long-term functional impairment.

The records of 58 patients who had hallux rigidus and were treated with cheilectomy between 1977 1984 showed the following results: 53.4% completely satisfactory, 19% mostly 27.6% unsatisfactory. No deterioration results time was apparent. When analyzed in relation to degenerative changes that evident preoperative roentgenograms, failure rate increased from 15% Grade I 37.5% III changes. Cheilectomy is procedure choice

Various radiographic measurements of the normal adult foot have been reported in both early and recent literature; however, a complete description quantitative data has yet to be reported. The purpose this study is describe range using standard techniques that can applied clinical setting. This should provide necessary for accurate interpretation radiographs. demonstrates wide variation bony relationships foot. When certain recognized criteria were evaluated, some found defined as too narrow...

The chevron osteotomy for realignment of the first metatarsal head in metatarsus primus varus deformity has been utilized at Mayo Clinic since 1976 on 26 feet (18 patients). Follow-up evaluation disclosed excellent relief pain, good cosmetic correction, and overall patient satisfaction. Radiographic demonstrated reduction angle between phalanx bone great toe as well narrowing forefoot with a decreased second bones. stability osteotomy, technical ease, absence secondary difficulties such...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetic partitioning between the exonuclease and polymerase sites in DNA error correctionMaureen J. Donlin, Smita S. Patel, Kenneth A. JohnsonCite this: Biochemistry 1991, 30, 2, 538–546Publication Date (Print):January 15, 1991Publication History Published online1 May 2002Published inissue 15 January 1991https://pubs.acs.org/doi/10.1021/bi00216a031https://doi.org/10.1021/bi00216a031research-articleACS PublicationsRequest reuse permissionsArticle...

We evaluated the effects of therapy with a small dose (0.5 microgram/day) 1,25-dihydroxyvitamin D3 in 12 previously untreated patients postmenopausal osteoporosis. Combined radiocalcium kinetic and balance studies showed that at base line, net calcium absorption (mean +/- SEM) was low (7 3%), negative (-59 22 mg/day), bone resorption rate (297 40 mg/day) exceeded formation (239 36 mg/day). After short-term (6-8 months), normal (27 3%, P less than 0.001 for difference from line), had improved...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElementary steps in the DNA polymerase I reaction pathwayF. R. Bryant, K. A. Johnson, and S. J. BenkovicCite this: Biochemistry 1983, 22, 15, 3537–3546Publication Date (Print):July 19, 1983Publication History Published online1 May 2002Published inissue 19 July 1983https://pubs.acs.org/doi/10.1021/bi00284a001https://doi.org/10.1021/bi00284a001research-articleACS PublicationsRequest reuse permissionsArticle Views402Altmetric-Citations152LEARN ABOUT...

The results of all Chevron osteotomies for hallux valgus performed at the Mayo Clinic between January 1976 and June 1982 were reviewed least 1 year after surgery. Of total 157 patients with 228 operations eligible inclusion in this study, 154 225 interviewed. Complete satisfaction was expressed 79.1% procedures, minor reservations 12.9%, dissatisfaction 8%. For producing incomplete satisfaction, further investigation identified failure to achieve correction technical errors as most prominent...

Splenomegaly confirmed by surgery or necropsy in 100 dogs was diagnosed histologically as benign neoplasia (n = 1), primary splenic malignancy 59), neoplastic metastases 6), and nonneoplastic disease 34). Dogs with known systemic disease, such lymphoma mast cell tumor, that caused splenomegaly were not included the study. Hemangiosarcoma most common (43 cases). Overall mean age of 10.7 years, breed German Shepherd dog, 72 weighed more than 21 kg. anemia, nucleated red blood cells, abnormal...

The sequential approach to evaluating the cavus foot is integrated with a description and assessment of various treatment options. Decision making in these cases complicated by progressive neurologic condition that underlies many deformities. An effort made recommend most appropriate surgical intervention based on nature deformity its rigidity. Although principles apply all feet, Charcot-Marie-Tooth disease difficult treat prone recurrence because muscular imbalance causing it.

Success of block the sciatic nerve in popliteal fossa 130 patients was assessed by an anesthesiologist at time surgery. The were evaluated for complications during postoperative rounds and orthopedic surgeon 1-month follow-up visit. Acceptance patient judged answers on a questionnaire filled out after they had gone home. designed to determine satisfaction with block, discomfort associated performance whether sensations suggestive paresthesias or other not evident discharge from hospital...

Subtalar dislocations are uncommon injuries. In an effort to obtain accurate information, eight recent major series (more than five patients) were summarized, including the experience at authors' institution between 1975 and 1985 (12 patients). Medial predominated (79.5%), lateral injuries accounted for 17% of cases, posterior (2.5%) anterior (1%) infrequent. Associated fractures with medial (55%) (72%) common. Open (25%) more common, avascular necrosis was (4%-5%). Males (81%). It evident...

Combined autogenous iliac-crest bone-grafting and fixation with a pin or screw was used to achieve fusion of the talocalcaneal joint in forty-one adults (forty-five arthrodeses). At mean length follow-up fifty-seven months (range, thirty ninety-six months), thirty-seven (90 per cent) patients were satisfied result. Objectively, results excellent after thirty-nine arthrodeses (87 cent), good fair five (11 poor one (2 cent). There non-union superficial wound infection. time follow-up, no...

Nineteen patients underwent surgical synovectomy and debridement for the clinical diagnosis of stage I posterior tibial tendon (PTT) dysfunction. Stage PTT dysfunction is characterized by pain swelling along medial aspect ankle. Fourteen (74%) reported complete relief pain, 3 (16%) minor 1 patient (5%) had moderate continued severe pain. Sixteen (84%) subjectively being “much better” a return function PTT, as evidenced their ability to perform single limb-heel-rise test. Two (10%) subtalar...

A late complication of fracture with dislocation involving the tarsometatarsal joints foot (Lisfranc fracture) is progressive degenerative arthritis and pain. dowel-graft arthrodesis technique described that uses percutaneous bone graft from iliac crest supplemented by crossed-wire fixation. The cases 15 patients who underwent surgery between 1979 1982 in which this was used were reviewed retrospectively. These suffered painful posttraumatic after joint fracture-dislocation. Follow-up...

Area moment of inertia for an object can be calculated by use mathematical equations, and is defined the dimensions object. modulus elasticity are principal factors determining bending stiffness. Because majority veterinary orthopaedic implants made 316L stainless steel, therefore have a similar elasticity, comparison area different provides estimate relative stiffness assist implant selection particular fracture. Knowledge this parameter may help avoid treatment complications, such as failure.

The hallux varus deformity results from a dynamic imbalance of the tendons that cross first metatarsophalangeal joint. This condition most frequently occurs after McBride-type operative treatment for valgus. A new procedure, developed to correct this imbalance, involves transferring extensor hallucis longus beneath intermetatarsal ligament into base proximal phalanx, along with an arthrodesis interphalangeal procedure in fifteen affected great toes gave over-all satisfactory correction deformity.