Introduction: Scrub typhus is a significant cause of acute encephalitis syndrome (AES) in pediatric populations, particularly northern India. Its long-term outcomes have not been well studied to date. This study investigates the clinical profile and scrub meningoencephalitis children. Methods: prospective observational was conducted at King George's Medical University, Uttar Pradesh, India, from August 2018 October 2020. Children aged 0.3 months 14 years who presented with AES were tested...

Managing West syndrome (WS) becomes arduous in regions where access to adrenocorticotropic hormone and vigabatrin is limited, particularly developing nations. This study aimed evaluate the efficacy of very high-dose oral prednisolone children diagnosed with WS. Children aged 2-36 months presenting WS were consecutively enrolled given @ 8 mg/kg/day (maximum 40 mg) for two weeks followed by tapering doses over subsequent weeks. Weekly follow-ups conducted until therapy completion, bi-weekly...

Autism is extraordinarily difficult for families to cope with various reasons. Perceived burden and care the child autism, available forms of social support, interactions between autistic other family members are areas significant concern families.The objective this study was determine perceived by principal caregivers children or adolescent visiting health facilities in Lucknow city.The cross-sectional conducted from October 2016 September 2017 a sample 90 (aged <60 years) adolescents aged...

Abstract Severe acute malnutrition (SAM) is a major cause of child mortality and morbidity. Children treated for SAM are at risk refeeding hypophosphataemia (HP). The study was done to find out the incidence various predictors moderate/severe HP in among North Indian children. This prospective observational conducted from August 2014 July 2015 inpatients’ department Department Paediatrics King George’s Medical University, Lucknow, Uttar Pradesh, India, tertiary care teaching hospital. Before...

Objective: To describe the clinical-laboratory profile of pediatric Guillain-Barre syndrome and delineate features associated with need mechanical ventilation. Methods: In a prospective observational study at tertiary care hospital, assessment nerve conduction studies were documented in consecutive children hospitalized according to Brighton criteria. Clinical-laboratory compared between ventilated nonventilated patients using univariate multivariate analysis. Results: Forty-six (27 boys)...

Spotted Fever Rickettsiosis (SFR), an acute febrile illness caused by Rickettsia rickettsii, R. conorii and akari which is associated with considerable morbidity mortality. SFR one of the most covert emerging infections present time prevalent in various parts India as shown increase number clinically diagnosed patients states except Uttar Pradesh.To diagnose suspected using serological tests recognition common epidemiologic situations clinical manifestations state Pradesh.Patients all age...

Meningoencephalitides (ME) are an important group of disorders that constitute a medical emergency in any age group, more so children. The physician uses the lumbar puncture (LP) as diagnostic test to confirm or exclude diagnosis ME. Of all LPs ordered, ME is found only small proportion. need for LP often alarming family. accuracy different clinical symptoms and signs may therefore help being discriminative use LP. Pediatric wards teaching hospital Northern India. Consecutive children...

Tuberculous meningitis (TBM), the severest form of tuberculosis, continues to affect children in India. The disease has a high rate mortality and disabling consequences. Scarce literature exists on prognostic indicators none radiological features. Our aim is delineate clinical, laboratory childhood TBM. Children with TBM diagnosed according pre-decided criteria admitted teaching hospital Northern India were enrolled for study. Demographic, radiologic features at admission charted. Patients...

Sjogren Larsson Syndrome (SLS) is an uncommon autosomal recessive disorder characterized by intellectual disability, congenital icthyosis and spastic diplegia.Here we report three siblings with SLS from Indian family no history of consanguinity.One sibling had unusual features spasticity tremors in upper limbs.

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Background: To determine prevalence rate of leptospirosis and recognition common epidemiological situation clinical manifestation in patients with pyrexia unknown origin at a tertiary care centre.Methods: This were hospital based prospective observational study. The duration study was from August 2015 to July 2016. Patients symptoms attending Gandhi Memorial Associated Hospital, King George’s Medical University Lucknow during the period enrolled this We performed IgM ELISA PCR for our centre...

Background: Acute encephalitis syndrome (AES) is a serious public health problem in Northern India.Neuroleptospirosis presenting as AES well documented, so this study was planned to know thecontribution of Neuroleptospirosis AES, children. Another gap leptospirosis research lack ofstudies on confirmed cases children.Aims: The aim look for contribution Pediatric AESpatients, part the country.Method: All children with AES-like presentations were included. Detailed history, clinical...