- Fungal Biology and Applications
- Enzyme-mediated dye degradation
- Lignin and Wood Chemistry
- Phytochemistry and Bioactivity Studies
- Biofuel production and bioconversion
- Medicinal Plants and Bioactive Compounds
- Mycorrhizal Fungi and Plant Interactions
- Biochemical and biochemical processes
- Phytochemicals and Antioxidant Activities
- Medicinal plant effects and applications
- Biocrusts and Microbial Ecology
- Herbal Medicine Research Studies
- Bee Products Chemical Analysis
- Pharmacological Effects of Natural Compounds
- Microbial Metabolic Engineering and Bioproduction
- Silymarin and Mushroom Poisoning
- Slime Mold and Myxomycetes Research
- Chromium effects and bioremediation
- Agriculture, Plant Science, Crop Management
- Phytochemical compounds biological activities
- Chemical synthesis and alkaloids
- Tryptophan and brain disorders
- Complementary and Alternative Medicine Studies
- Essential Oils and Antimicrobial Activity
- Exercise and Physiological Responses
University of Belgrade
2014-2023
Kyiv City Clinical Oncology Center
2019
Institute for Plant Protection and Environment
2017
Structural component of plant biomass, lignocellulose, is the most abundant renewable resource in nature. Lignin recalcitrant natural aromatic polymer and its degradation presents great challenge. Nowadays, special attention given to biological delignification, process where white-rot fungi take crucial place owing strong ligninolytic enzyme system. However, fungal species, even strains, differ potential produce high active enzymes consequently delignify biomass. Therefore, goals study were...
Various neurodegenerative diseases are the main challenges to modern medicine and there is a great need for novel, natural, neuroprotective agents. Ganoderma lucidum well‐known medicinal mushroom, which health benefits have been confirmed by numerous studies. As demand its basidiocarps increased traditional cultivation on hardwoods not environmentally friendly economically justified, finding of alternative substrates necessary. The aim study was assess effect chemical profile G . their...
Basidiocarps of Pleurotus ostreatus and Agrocybe cylindracea are characterized by high nutritional value numerous medicinal activities, though bioactivities their mycelia have not been sufficiently studied. The aim the study was to evaluate antioxidant antifungal potentials P. A. basidiocarp extracts, as well those obtained from cultivated in common synthetic medium media enriched with various agro-industrial residues. free radical scavenging activity extracts determined...
Trametes hirsuta is an efficient lignin-degrading species due to its ability produce laccase and Mn-dependent peroxidase. Agricultural residues represent prospective substrates for the bioconversion into fungal biomass lignocellulolytic enzymes, but also they could be potential environmental pollutants. Evaluation of T. ligninolytic enzymes during solid-state fermentation selected plant raw materials was goal study. The highest level activity (3827.0 ± 219.0 U/L) noted in mandarin orange...
The study aimed to evaluate the antiradical and antimicrobial (antibacterial antifungal) potentials of ethanol mycelial extracts selected Ganoderma species strains define interand intraspecies diversity among strains. lucidum were good DPPH• scavengers (neutralizing up 57.12% radicals), contrary G. applanatum (20.35%) carnosum (17.04%). High correlations between activities contents total phenols in showed that these compounds carriers activity. Results obtained by both discdiffusion...
Abstract Wheat straw is the major crop residue in European countries which makes it most promising material for bioconversion into biofuels. However, cellulose and hemicellulose are protected with lignin, so delignification an inevitable phase lignocellulose processing. The organisms predominantly responsible its degradation white-rot fungi among them Trametes species represent degraders due to a well-developed ligninolytic enzyme system. Although numerous studies have confirmed that low...
The scientific interest in the medicinal properties of Kombucha beverages, a carbonated drink with live microorganisms, has increased recently. Hence, aim this study was to determine chemical profile and examine antioxidant, antidiabetic antineurodegenerative potential unfermented also fermented Camellia sinensis (green tea), Coffea arabica (coffee), Ganoderma lucidum (Reishi) extracts. extracts were prepared as follows: first (unfermented) set contained 1 L water, 50 g sucrose 20 dried...
The goal of this study was the evaluation antifungal, antioxidant and anticancer potentials Pleurotus eryngii, P. ostreatus pulmonarius mycelial extracts, influence mycelium enrichment with selenium on these activities. Both Se-amended non-amended extracts showed same or similar minimal inhibitory concentration for 14 studied micromycetes, while a fungicidal effect not noted, contrary to ketoconazole, which had effects at very low concentrations. Se-non-amended exhibited activity, especially...
The bioactivity of Ganoderma lucidum basidiocarps has been well documented, but there are no data on the medicinal properties its submerged cultivation broth nor other species genus Ganoderma. Thus aim this study was to test potential antimicrobial and antioxidant activity fermentation obtained after G. applanatum, carnosum, lucidum. DPPH· scavenging ability, total phenols, flavonoid contents were measured determine antioxidative spp. filtrates, whereas their studied using microdilution...
Ganoderma lucidum has a well-developed ligninolytic enzyme system, where laccase is the dominant and sometimes only synthesizing enzyme, therefore could find an application in delignification of abundant plant raw materials food, feed, paper, biofuel production.The questions that provided goals for present study were whether profile G. depends on cultivation type carbon source, as well intraspecific diversity exists.Conditions submerged proved more preferable activity compared with...
Oxidative stress, which is a factor in the aging process and series of serious disorders, arises when reactive oxygen or nitrogen species are produced excess capacity cellular antioxidant defense insufficient to detoxify remove them. An internal system not always active enough protect human body from oxidative stress and, therefore, it needs help either synthetic natural antioxidants. Nowadays, there growing interest substitution antioxidants, could have toxic mutagen effects, with Recent...
The aim of the study was an assessment antioxidant, antifungal and cytotoxic potentials L. betulinus T. hirsuta mycelia extracts effect selenium on these activities. Extracts were twice as efficient in DPPH• scavenging those hirsuta. phenol content Se-enriched higher than non-enriched extracts, contrast to Se-enrichment a direct correlation between amount observed. Ethanol exhibited fungistatic but not fungicidal activity against range micromycetes, mycelium enrichment with inhibited this...
Previous studies showed that some mushrooms are highly efficient in inhibiting acetylcholinesterase and tyrosinase, the increased activity of which can trigger development Alzheimer Parkinson diseases. Starting from fact free radicals at high concentrations could cause neurodegenerative disorders as well great interest new, natural antineurodegenerative drugs, goal this study was to determine vitro antioxidative neuroprotective potentials various Pleurotus ostreatus Laetiporus sulphureus...
Grifola frondosa HAI 1232 was tested for ligninolytic enzyme activities and lignin, cellulose hemicellulose degradation during cultivation on eight common agro-forestry residues in Serbia. Wheat straw favorable lignocellulosic the production of Mn-dependent Mn-independent peroxidases (2513.89 354.17 U L-1, respectively), while selected inhibited synthesis laccases. The highest lignin removal observed fermentation blackberry sawdust (36.75%), selectivity index recorded oak (4.34). dry matter...
Demand for Ganoderma lucidum basidiocarps on the global market is increased due to its numerous health benefits. As they are rare in nature and traditional cultivation logs not ecologically economically justified method, current trend finding of good alternative substrate production. Whether wheat straw, most abundant crop residue Europe, could be a novel G. was question which led definition goals. Two wild one commercial strains were objects study. Despite some morphological differences...
Agro-forestry residues are a widespread lignocellulosic biomass, which could be used as raw material in many industries.The essential precondition for their usage is delignification, process where white-rot fungi have crucial role due to powerful ligninolytic enzyme system.The objectives of this study were investigate the insufficiently studied potential Auricularia auricula-judae by determining its Mn-oxidizing peroxidase and laccase activities, well capacity lignin, hemicellulose cellulose...
Abstract The goal of this study was to determine the capacity Pleurotus spp. lignocellulosome transform frequent pomiculture residues (grapevine-, plum-, and raspberry sawdust) into raw materials for biotechnological processes. All three lignocellulosics induced synthesis ligninolytic cellulolytic enzymes in tested species. Laccase dominant cocktail, with a maximum activity 40,494.88 U L −1 observed after cultivation P. pulmonarius on grapevine sawdust. Grapevine sawdust also proved be...
Trunks and stumps of various deciduous species act as natural habitats for Ganoderma lucidum. The chemical composition their cell wall affects the development fungal ligninolytic enzyme system well its ability to degrade lignin from plant wall. Additionally, numerous compounds structurally similar can be degraded by G. lucidum which could take important roles in biotechnological processes. laccases, are dominant enzymes synthesized lucidum, have been studied more extensively than...