A5076476341- Vaccine Coverage and Hesitancy
- Health Systems, Economic Evaluations, Quality of Life
- Pneumonia and Respiratory Infections
- Economic and Financial Impacts of Cancer
- Global Cancer Incidence and Screening
- Cervical Cancer and HPV Research
- Herpesvirus Infections and Treatments
- Respiratory viral infections research
- Bacterial Infections and Vaccines
- Multiple and Secondary Primary Cancers
- Child and Adolescent Health
- Hepatitis Viruses Studies and Epidemiology
- Global Health Care Issues
- Colorectal Cancer Screening and Detection
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Pharmaceutical studies and practices
- Influenza Virus Research Studies
- Retinal and Optic Conditions
- Adolescent and Pediatric Healthcare
- Cancer Immunotherapy and Biomarkers
- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Cutaneous Melanoma Detection and Management
- Emergency and Acute Care Studies
MSD (Spain)
2020-2025
Merck & Co., Inc., Rahway, NJ, USA (United States)
2019-2024
MSD (Sweden)
2024
Karolinska Institutet
2024
GlaxoSmithKline (Croatia)
2015-2016
Importance Few studies have examined the incidence of long-term disabilities due to bacterial meningitis in childhood with extended follow-up time and a nationwide cohort. Objective To describe risks following diagnosis Sweden. Design, Setting, Participants This retrospective registry-based cohort study included individuals diagnosed (younger than 18 years) general population controls matched (1:9) by age, sex, place residence. Data were retrieved from Swedish National Patient Register...
Infections are responsible for approximately 13% of cancer cases worldwide and many these infections can be prevented by vaccination. Human papillomavirus (HPV) hepatitis B virus (HBV) among the most common that cause deaths globally, despite effective prophylactic vaccines being available. This analysis aims to estimate global burden economic impact vaccine-preventable mortality across World Health Organization (WHO) regions.
Abstract Background Immunization programs, by preventing infectious diseases for which antibiotics are prescribed, have the potential to reduce antibiotic use and development of antimicrobial resistance. However, limited data available regarding impact vaccines on prescribing at population level. This study evaluated pediatric immunization prescribed treatment courses in United States (US).Table 1.Antibiotic Usage Assumptions Disease Methods A previously published decision tree model was...
Background Cancer is the second leading cause of death in Asia-Pacific region. Human papillomavirus (HPV) and hepatitis B virus (HBV) are major cancer-causing infections. This analysis assessed mortality impact productivity losses due to HBV- HPV-related cancers ten countries.
Background: In a previous study, we explored real-world programmed death-ligand 1 (PD-L1) testing and treatment patterns for patients with advanced non-small cell lung cancer (NSCLC) in the era of immune-oncology. The present study aimed to investigate overall survival (OS) PD-(L)1 inhibitors longer-term follow-up Swedish setting. Materials methods: Data were extracted from National Lung Cancer Registry NSCLC stage IIIB-IV ECOG performance status (PS) 0–2 who initiated first-line systemic...
Vaccine hesitancy is listed as one of the top 10 global health threats by WHO. Existing studies investigating relationship between vaccine and social media have found that misinformation concerns on can cause significant declines in coverage rates. The objective this study was to provide insight into dynamics messages Twitter Scandinavia (Denmark, Norway, Sweden), analyzing tweets local languages during 2019. A validated measure, 5C scale, used map relevant predictors vaccination behavior,...
Breast cancer (BC) poses a public health challenge as the most commonly diagnosed among women globally. While BC mortality has declined across Europe in past three decades, an opposite trend been reported some transitional European countries. This analysis estimates burden and cost of lost productivity due to deaths nine Central Eastern (CEE) countries: Bulgaria, Croatia, Czech Republic, Hungary, Poland, Romania, Serbia, Slovakia, Slovenia, that have defied favorable trends. These may...
Pneumococcal disease is a major cause of clinical and economic burden worldwide. This study investigated the pneumococcal in Swedish adults. A retrospective population-based was conducted using national registers, including all adults aged ≥18 years with diagnosis (defined as pneumonia, meningitis, or septicemia) inpatient outpatient specialist care between 2015-2019. Incidence 30-day case fatality rates, healthcare resource utilization, costs were estimated. Results stratified by age...
Abstract Aims The aim of this systematic literature review was to provide updated information on human papillomavirus (HPV) prevalence in locally and regionally advanced (LA) recurrent/metastatic (RM) head neck cancer (HNC) worldwide. Methods Electronic searches were conducted clinicaltrials.gov , MEDLINE/PubMed, Embase, ASCO/ESMO journals congresses for interventional studies (IS; Phase I–III trials) as well MEDLINE Embase non‐interventional (NIS) LA/RM HNC published between January 01,...
Lung cancer accounts for approximately 20% of all cancer-related deaths and the loss 3.2 million disability-adjusted life years (DALYs) annually across Europe. The present study investigated productivity losses resulting from premature due to lung in four European countries.The human capital approach (HCA) was used estimate indirect cost death (ICD-10 codes C33-34 malignant neoplasm trachea, bronchus, lung) Belgium, Netherlands, Norway, Poland. Years productive lost (YPLL) value future...
Background This study provides an updated and expanded analysis of the impact COVID-19 pandemic on routine vaccinations across life-course in United States.Research design methods Routine wellness visits vaccination rates were calculated using structured claims data for each month during period (January 2020 to August 2022) compared respective baseline 2018 December 2019). Monthly aggregated as annual accumulated cumulative percent changes.Results The complete monthly rate interactive...
The treatment landscape for patients with advanced non-small cell lung cancer (NSCLC) has evolved significantly since the introduction of immunotherapies. We here describe PD-L1 testing rates, patterns, and real-world outcomes PD-(L)1 inhibitors in Sweden.
Background The economic and mortality burden of cancer is high worldwide. In Europe, was responsible for 1.3 million deaths in 2020 incurred an estimated cost €50 billion from premature mortality. Human papillomavirus (HPV) hepatitis B virus (HBV) are among the leading causes infection-related cancers despite availability effective vaccines against these infections. This analysis productivity loss HBV- HPV-associated that could be preventable through vaccination across European regions.
Background Infections are responsible for ∼13% of cancer cases worldwide, with human papillomavirus (HPV) and hepatitis B (HBV) among the infections associated which vaccines available. The aim this study was to estimate indirect cost premature mortality related cancers caused by HPV HBV in Middle East North Africa (MENA) countries.
Background Varicella is usually a mild disease in children but may be life-threatening, especially adolescents and adults. Infection control measures implemented during the Coronavirus Disease 2019 (COVID-19) pandemic have suppressed varicella transmission, potentially creating an ‘immunity debt’, particularly countries without universal vaccination. Objectives To assess trends Google search engine queries for keywords as proxy infection rates to evaluate effect of vaccination on these...
Human papilloma virus (HPV) is a common cause of several types cancer, including head and neck (oral cavity, pharynx, oropharynx, hypopharynx, nasopharynx, larynx), cervical, vulval, vaginal, anal, penile cancers. As HPV vaccines are available, there potential to prevent HPV-related disease burden related costs.
Objective We evaluated the public health impact and return on investment of Belgium’s pediatric immunization program (PIP) from both healthcare-sector societal perspectives. Methods developed a decision analytic model for 6 vaccines routinely administered in Belgium children aged 0–10 years: DTaP-IPV-HepB-Hib, DTaP-IPV, MMR, PCV, rotavirus, meningococcal type C. used separate trees to each 11 vaccine-preventable pathogens: diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae...
V114, a 15-valent pneumococcal conjugate vaccine (PCV15) currently approved in adults the US, contains 13 S. pneumoniae serotypes PCV13 and two additional serotypes, 22 F 33 F, which are important contributors to residual PD. This study quantified health economic burden of pediatric invasive disease (IPD) associated with V114 eight countries Europe.A Markov model estimated V114-type IPD cases costs hypothetical unvaccinated birth cohorts from Denmark, France, Germany, Italy, Norway, Spain,...
In 2018, 371,750 people were diagnosed with kidney cancer globally, constituting 2.2% of all diagnoses. Since 2010, the number deaths in Europe have decreased under 65. However, this is not case Greece and Portugal. This study estimated mortality lost productivity due to premature from Portugal.Years life (YLL) present value future (PVFLP) (ICD-10 code: C64 - Malignant neoplasm kidney, except renal pelvis) calculated using human capital approach. Age-specific mortality, mean earnings, labor...