- Enzyme Catalysis and Immobilization
- Fatty Acid Research and Health
- Lipid metabolism and biosynthesis
- Analytical Chemistry and Chromatography
- Microbial Metabolic Engineering and Bioproduction
- Phase Equilibria and Thermodynamics
- Cholesterol and Lipid Metabolism
- Edible Oils Quality and Analysis
- Food Chemistry and Fat Analysis
- Diet and metabolism studies
- Proteins in Food Systems
- Biomedical Research and Pathophysiology
- Electrochemical sensors and biosensors
- Essential Oils and Antimicrobial Activity
- Process Optimization and Integration
- Glioma Diagnosis and Treatment
- Algal biology and biofuel production
- Free Radicals and Antioxidants
- Chemical Thermodynamics and Molecular Structure
- Antioxidant Activity and Oxidative Stress
- biodegradable polymer synthesis and properties
- Ionic liquids properties and applications
- Infant Nutrition and Health
- Diet, Metabolism, and Disease
- Biochemical Analysis and Sensing Techniques
Universidad Autónoma de Madrid
2013-2024
Instituto de Investigación en Ciencias de la Alimentación
2013-2024
Consejo Superior de Investigaciones Científicas
1996-2020
San Jose State University
2008-2012
University of Rochester
1980-2005
University of Wisconsin–Madison
2001-2004
Instituto de Catálisis y Petroleoquímica
1995-2001
Universidad Complutense de Madrid
1992-1995
Children's Hospital of Philadelphia
1994
University of Tennessee Health Science Center
1982
Abstract Five familial cases (in two families) and one sporadic case of a new congenital myasthenic syndrome were investigated. Symptoms arise in infancy or later life. Typically, finds selective involvement cervical, scapular, finger extensor muscles, ophthalmoparesis, variable other muscles. There is repetitive muscle action potential to single nerve stimulus all muscles decremental response at 2 3 Hz stimulation clinically affected Microelectrode studies reveal markedly prolonged...
The standard follow-up care for children with medulloblastoma includes regular clinical evaluations and surveillance scanning of the central nervous system computed tomography or magnetic resonance imaging. assess response tumor to treatment, detect any recurrence disease, monitor complications treatment. We compared effectiveness a periodic history taking physical examination that in detecting recurrent tumors.
Although acetazolamide usually prevents paralytic attacks in hypokalemic periodic paralysis, not all patients benefit from this treatment. We studied a father and two sons whom attack frequency severity increased on acetazolamide. Administration of triamterene virtually abolished three separate single-blind trials totaling more than 12 months. Spontaneous glucose-insulin provoked occurred with only slight hypokalemia. Acetazolamide produced hypokalemia weakness whereas potassium levels...
The oxidative stability of microalgae oil (MO) and its enzymatic glycerolysis product (GP) have been determined by using the accelerated oxidation methods differential scanning calorimetry (DSC) Rancimat at temperatures in range 50–90 °C. Kinetic analyses MO GP provide Arrhenius activation energy enthalpy entropy, temperature coefficients, Q10 index 20 °C (OSI20), based on secondary tertiary products. Susceptibility to has compared that fish vegetable oils, with OSI20 values 647 h for 381...
A predigested product from arachidonic acid oil (ARA) and docosahexaenoic (DHA) in a 2:1 (w/w) ratio has been developed evaluated an vitro digestion model. To produce this lipid mixture, first, the two oils were enzymatically hydrolyzed up to 90% of free fatty acids (FFAs) achieved. Then, these (FA) mixtures mixed ARA-to-DHA esterified with glycerol mixture FFAs, mono-, di-, triacylglycerides. Different ratios temperatures evaluated. The best results attained at 10 °C glycerol-to-FA molar...
Abstract Enzymatic esterification and supercritical fluid extraction was used to produce phytosterol esters from soybean oil deodorizer distillates. The raw material first subjected a two‐step enzymatic reaction; the product obtained mainly comprised fatty acid ethyl esters, tocopherols together with minor amounts of squalene, free acids, sterols triacylglycerols. were then purified this mixture using carbon dioxide. Experimental extractions carried out in an isothermal countercurrent column...
Ethanolysis of shark liver oil was carried out to generate a product enriched in nonesterified alkoxyglycerols and fatty acid ethyl esters. For the present study, original contained very low amounts squalene, thus, unsaponifiable matter mainly constituted by (NEAKG). A small percentage monoesterified (MEAKG) also detected. Supercritical fluid extraction employed fractionate mixture, achieving complete elimination esters concentrating alkoxyglycerol compounds raffinate product. Extractions...