- Photonic and Optical Devices
- Semiconductor Lasers and Optical Devices
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Advanced Photonic Communication Systems
- Advanced Fiber Laser Technologies
- Glaucoma and retinal disorders
- Nonlinear Optical Materials Research
- Spectroscopy and Laser Applications
- Astro and Planetary Science
- Ocular Infections and Treatments
- Retinal Diseases and Treatments
- Electric Vehicles and Infrastructure
- Optical Coherence Tomography Applications
- Advanced Battery Technologies Research
- Ocular Surface and Contact Lens
- Atmospheric and Environmental Gas Dynamics
- Inertial Sensor and Navigation
- Laser Design and Applications
- Photonic Crystal and Fiber Optics
- Spacecraft Design and Technology
- Advanced optical system design
- Corneal Surgery and Treatments
- Immune Response and Inflammation
Empire Eye Physicians
2012-2023
California Institute of Technology
2005-2021
Jones College
2021
Taiwan Semiconductor Manufacturing Company (Taiwan)
2020
Johnson & Johnson (United States)
2019
Bakersfield College
2015
RTX (United States)
2013
Loma Linda University
2006-2012
Loma Linda University Medical Center
2012
The University of Adelaide
2012
To compare the accuracy of intraocular lens (IOL) power calculations using 4 formulas: Hoffer Q, Holladay 1, 2, and SRK/T.Tertiary care center.This study was a retrospective comparative analysis. Immersion ultrasound biometry (axial length, anterior chamber depth, thickness), manual keratometry, postoperative manifest refraction were obtained in 643 eyes consecutive patients who had routine uneventful cataract surgery with implantation 1 2 IOLs same operative technique by surgeon. Biometric...
We describe the architecture and algorithms of Adaptive Charging Network (ACN), which was first deployed on Caltech campus in early 2016 is currently operating at over 100 other sites United States. The enables real-time monitoring control supports electric vehicle (EV) charging scale. ACN adopts a flexible Scheduling Algorithm based convex optimization model predictive allows for significant over-subscription electrical infrastructure. some practical challenges real-world systems, including...
Based on a nonlinear optical polymer with highly chromophore (CLD) dispersed in an amorphous polycarbonate (APC), we have developed electrooptic (EO) modulators operating at 1550-nm wavelength low loss and good thermal stability. By incorporating insulation layer, push-pull poling was successfully performed without film damages. We also demonstrated that the propagation of EO waveguide could be reduced as 1.2 dB/cm 1550 nm when large core structure incorporated. The long-term reliabilities...
The concept of antiinflammatory effects volatile anesthetics is well established in vitro and some organ systems. Their protective role lung injury, however, remains to be elucidated. authors hypothesized that the lung, isoflurane pretreatment may attenuate neutrophil infiltration reduce endotoxin-induced injury.Male C57Bl/6 mice were exposed aerosolized lipopolysaccharide. Neutrophil recruitment into pulmonary vasculature migration different compartments (interstitium alveolar air space)...
Abstract To determine the role of adenosine receptor A2a in a murine model LPS-induced lung injury, migration polymorphonuclear leukocytes (PMNs) into different compartments was determined by flow cytometry, microvascular permeability assessed extravasation Evans blue, and release chemotactic cytokines alveolar airspace ELISA. Measurements were performed wild-type gene-deficient mice (A2a−/−). differentiate on hemopoietic nonhemopoietic cells, we created chimeric transfer bone marrow (BM)...
Purpose: To compare the clinical performance of TECNIS Synergy intraocular lens (IOL), model ZFR00V, vs IOL, ZCB00, in cataract patients. Setting: Multicenter setting. Design: Prospective, randomized, subject/evaluator-masked trial. Methods: Cataract patients aged ≥22 years were randomly assigned 1:1 to bilateral implantation with ZFR00V or ZCB00. Key end points at 6 months postsurgery included monocular and binocular visual acuities 4 m, 66 cm, 33 and/or 40 distance-corrected defocus...
Push–pull polymeric electro-optic Mach–Zehnder (MZ) modulators with Vπ of 1.2 and 1.8 V at 1310 1550 nm, respectively, an interaction length 2 cm are demonstrated. These devices were made from second-order nonlinear optic guest–host polymers that consisted a phenyltetraene bridged high μβ chromophore guest amorphous polycarbonate host. Poling was done in N2 atmosphere to avoid bleaching by oxidation. A MZ-like two-arm microstrip line used as the driving electrode these devices. The optical...
Large-scale charging infrastructure will play an important role in supporting the adoption of electric vehicles. In this paper, we address prohibitively high capital cost installing large numbers stations within a parking facility by oversubscribing key pieces electrical infrastructure. We describe unique physical testbed for large-scale, high- density EV research which call Adaptive Charging Network (ACN). architecture ACN including its hardware and software components. also present...
Abstract The Duffy antigen receptor for chemokines (DARC) has a high affinity CC and CXC chemokines. However, it lacks the ability to induce cell responses that are typical classical chemokine receptors. role of DARC in inflammatory conditions remains be elucidated. We studied murine model acute lung injury. found Darc ‐gene‐deficient ( −/− ) mice, LPS‐induced PMN migration into alveolar space was elevated more than twofold. In contrast, adhesion endothelial cells within interstitial reduced...
Purpose: To compare the effectiveness and safety of TECNIS Symfony intraocular lens (IOL; ZXR00) with 1-piece monofocal IOL (ZCB00). Setting: 15 sites in United States. Design: Prospective, randomized, patient-masked/evaluator-masked clinical trial. Methods: Randomized participants received either ZXR00 or ZCB00 bilaterally. The 6-month postoperative outcomes included monocular binocular distance, intermediate, near visual acuity (VA), spherical equivalent refraction refractive cylinder,...
Integrated photonic radio frequency (RF) phase shifters with dc voltage control have been realized using a nested dual Mach-Zehnder modulator configuration in new nonlinear optical polymer, CLD2-ISX. These modulators V/sub /spl pi// of 10.8 V and exhibit excellent performance measured up to 20 GHz. A near linear shift exceeding 108/spl deg/ was obtained for 16-GHz microwave signal by tuning the over 7.8-V range. It is expected that these integrated polymer will find widespread applications...
Rationale: Excessive recruitment of polymorphonuclear leukocytes (PMNs) to the lung promotes acute injury (ALI). Chemokine receptors and adhesion molecules initiate leukocyte–endothelial interactions, but mediators PMN migration through alveolo-capillary membrane remain be identified. p21-Activated kinase (PAK) is an effector small GTPases has been implicated in cell migration.Objectives: To test role PAK ALI.Methods: An inhibitory peptide was used determine cytoskeletal actin...
To assess the experimental visual performance and dysphotopsia characteristics of new Tecnis Symfony OptiBlue extended-depth-of-focus with violet light-filtering (ZXR00V) intraocular lens (IOL) compared colorless (ZXR00) IOL.Range vision was assessed simulated acuity defocus curves, predicted by white light through focus modulation transfer function (MTF) measurements. The clinical curve ZXR00 IOL used to validate range vision. Image quality measuring MTF at a spatial frequency 15 cycles per...
Purpose. To assess the utility of donor corneoscleral rim cultures. Methods. A retrospective review culture results 774 rims that remained after trephination corneas for transplantation into patients at our academic medical center between January 1992 and November 1997. Results. Forty-one (5.3%) cultures yielded microorganisms, mostly coagulase-negative staphylococci. Two developed endophthalmitis (one with Staphylococcus aureus one Pseudomonas aeruginosa) within 3 months transplantation;...
An optoelectronic oscillator (OEO) producing a 39-GHz microwave signal has been demonstrated using novel electrode-poled push-pull polymer modulator. This is the highest reported OEO operating frequency to date. Preliminary measurement of phase noise shows performance in range commercial synthesizers and behavior with respect cavity length accordance theory. It also observed that dispersion penalty significant factor at this high frequency.
The aim of the study is to evaluate visual acuity and patient satisfaction at varied distances under photopic mesopic lighting conditions in patients bilaterally implanted with aspheric diffractive multifocal one-piece intraocular lenses.In this retrospective-prospective study, 16 a mean age 66.2±9.2 years (range: 50-81 years) who had undergone bilateral phacoemulsification surgery implantation Tecnis lens (ZMB00) were evaluated. Monocular binocular uncorrected distance-corrected acuities...
To evaluate the chicken cornea as a model for corneal wound healing research.We conducted studies on normal corneas and following mechanical debridement photorefractive keratectomy (PRK).The possesses six distinct layers that resemble of human cornea, including substantial Bowman's layer measuring 5.2 +/- 0.3 microm thick. Reepithelialization time was 44.8 1.1 hours with sliding rate 75.3 3.2 microm/hour 54.4 2.8 63.3 PRK-treated corneas. Biomicroscopic haze post-PRK peaked at 4-6 weeks...
This paper addresses the use of distributed coherent communication techniques across a wireless network tactical radios to enable extended-range communications. Conventional systems providing multi-kilometer terrestrial ranges utilize large and costly manpack or vehicular-mount radios. In this we discuss for distributing transmit functions coherently small, low-power squad achieve similar ranges. We present testbed implementation these over-the-air demonstrations communications at 3.5 km...
Millimeter (MM)-wave signals at frequencies up to 102 GHz have been time stretched down 11 using a new wide-band traveling-wave polymer modulator. This is the first application of electrooptic modulators fabricated material PC-CLD, which has demonstrated good optical loss and high nonlinearity 1.55 μm.
Polymeric APC-CPW electrooptic modulators incorporating an inverted-rib waveguide structure were fabricated and tested for the first time. The inverted greatly simplifies fabrication procedures, additionally improves propagation loss performance. Mach-Zehnder using this exhibited 6 dB of fiber-to-fiber insertion 2.3-cm length V driving voltage a one-arm micro-strip electrode 1.5-cm interaction length, at wavelength 1.55 μm.