A5086235741- Essential Oils and Antimicrobial Activity
- Curcumin's Biomedical Applications
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Ginger and Zingiberaceae research
- Bee Products Chemical Analysis
- Immune Response and Inflammation
- Piperaceae Chemical and Biological Studies
- Natural product bioactivities and synthesis
- Natural Antidiabetic Agents Studies
- Musculoskeletal pain and rehabilitation
- Trypanosoma species research and implications
- Medicinal Plants and Neuroprotection
- Drug-Induced Hepatotoxicity and Protection
- Cholinesterase and Neurodegenerative Diseases
- Traditional and Medicinal Uses of Annonaceae
- Synthesis and biological activity
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Diet, Metabolism, and Disease
- Berberine and alkaloids research
- Andrographolide Research and Applications
- Electrochemical sensors and biosensors
- Medicinal Plants and Bioactive Compounds
- Biological Activity of Diterpenoids and Biflavonoids
- Occupational Health and Performance
Forman Christian College
2019-2024
Armed Forces Institute of Pathology
2023
Riphah International University
2022
University of Sargodha
2022
Government College University, Lahore
2021
National University of Malaysia
2017-2018
Zingiber zerumbet rhizome and its bioactive metabolites have previously been reported to exhibit innumerable pharmacological properties particularly anti-inflammatory activities. In the present study, 80% ethanol extract, essential oil zerumbone of Z. rhizomes were explored for their in vitro immunosuppressive on chemotaxis, CD11b/CD18 expression, phagocytosis chemiluminescence isolated human polymorphonuclear neutrophils (PMNs).The extract was analyzed quantitatively by performing a...
Abstract Background Albizia richardiana belongs Fabaceae family which different parts like fruits, flowers, barks, and roots are used medicinally. The study reports the in vitro anti-inflammatory, thrombolytic, cytotoxicity antimicrobial activity of methanolic extract A. stem its fractions. Method (MEAR) extracted with n-hexane (HXFAR), carbon tetrachloride (CTFAR), chloroform (CFAR), aqueous (AQFAR) subjected for DPPH scavenging total phenol content (TPC). cytotoxic evaluated by brine...
Zingiber zerumbet rhizome has been used in traditional medicine mainly for the treatment of various immune-inflammatory related ailments and shown to exhibit a wide spectrum biological effects especially antioxidant anti-inflammatory activities. The present study was aimed investigate immunosuppressive standardized 80% ethanol extract Z. at 100, 200, 400 mg/kg on innate immune responses male Wistar rats. parameters determined were chemotaxis neutrophils, Mac-1 expression, engulfment...
Abstract Merremia vitifolia (Burm.f.) Hallier f., an ethnomedicinally important plant, used in the tribal areas to treat various ailments including fever, headache, eye inflammation, rheumatism, dysentery, jaundice and urinary diseases. The present study explored biological efficacy of aqueous fraction M. leaves (AFMV) through vitro vivo experimental models. thrombolytic anti-arthritic effects AFMV were evaluated by using clot lysis technique inhibition protein denaturation technique,...
Annona muricata</i> L. (Annonaceae) (AM)'s remarkable anti-inflammatory and anti-cancer activities make it a targeted plant to be explored for its immunomodulatory properties. Traditional practitioners have employed various components of AM cure variety ailments, including cancer, diabetes, inflammation.The present study evaluated the immunosuppressive effects 80% ethanol extract leaves in male Wistar rats on different parameters humoral cellular immune responses.AM leaf (AMLE) was analyzed...
Background: 3,5-Bis[4-(diethoxymethyl)benzylidene]-1-methyl-piperidin-4-one (BBP), a novel synthetic curcumin analogue has previously been shown to manifest potent immunosuppressive effects on the in vitro phagocytosis process of human neutrophils. Objective: In present study, BBP was investigated for it's vivo innate and adaptive immune responses mediated by different humoral cellular factors. Methods: Male Balb/c mice were orally fed with (5, 10 20 mg/kg) period 14 days immunized sheep red...
Background: 3,5-Bis[4-(diethoxymethyl)benzylidene]-1-methyl-piperidin-4-one (BBP), a novel synthetic curcumin analogue has been revealed to possess strong in vitro and vivo immunosuppressive effects. Purpose: The aim of present study was prepare characterize BBP-encapsulated polylactic-co-glycolic acid-block-polyethylene glycol (PLGA-b-PEG) nanoparticles evaluate its efficacy against innate adaptive immune responses. Methods: Male BALB/c mice were orally administered with BBP alone BBP-...