Abstract Editor’s Perspective What We Already Know about This Topic Article Tells Us That Is New Background Previous research has shown different effects of anesthetics on cancer cell growth. Here, the authors investigated association between type anesthetic and patient survival after elective colon surgery. Methods A retrospective cohort study included patients who received surgery January 2005 December 2014. Patients were grouped according to anesthesia received: propofol or desflurane....

Processing electroencephalogram (EEG) monitors, such as bispectral index (BIS) monitoring to monitor patients' depth of anaesthesia, play a key role in ensuring patient safety and surgical success.[1,2] However, these systems are affected by many factors, including hypercapnia.[3,4] Understanding the effect hypercapnia on BIS correct interpretation is crucial for anaesthetists. Here, we share case sudden drop accompanied alpha beta wave dropout theta arousal density spectral array (DSA)...

Background Breast cancer is the most common in women and several perioperative factors may account for tumor recurrence metastasis. The anesthetic agents employed during surgery might play a crucial role cell survival patient outcomes. We conducted retrospective cohort study to investigate relationship between type of anesthesia overall patients who underwent breast performed by one experienced surgeon. Methods All an surgeon January 2006 December 2010 were included this study. Patients...

Abstract Previous researches have shown that anesthesia can affect the outcomes of many kinds cancer after surgery. Here, we investigated association between and patient elective open intrahepatic cholangiocarcinoma This was a retrospective cohort study patients who received surgery January 2005 December 2014. Patients were grouped according to received, is, propofol or desflurane anesthesia. Kaplan–Meier analysis performed survival curves constructed from date death. After propensity...

Postoperative sore throat (POST) is a minor complication of general anesthesia with tracheal intubation but may negatively affect patient satisfaction and postoperative recovery. The shape the endotracheal tube (ETT) cuff influence incidence severity POST. This prospective, randomized, double-blinded study was conducted on 174 female patients breast cancer. They were randomized into cylindrical (CYL) (group C) tapered (TAP) T) ETT groups. Data demographics, surgical characteristics, factors...

Anesthetic techniques can contribute to reduction of anesthesia-controlled time improve operating room (OR) efficiency. However, little is known about the difference in between propofol-based total IV anesthesia (TIVA) and desflurane (DES) for ophthalmic surgery under general anesthesia.We performed a retrospective analysis using hospital databases compare times patients receiving either TIVA via target-controlled infusion with propofol/fentanyl or desflurane/fentanyl-based January 2010...

Previous researches have shown that anesthetic techniques can influence the patient outcomes of cancer surgery. Here, we studied relationship between type and following elective, open pancreatic surgery.This was a retrospective cohort study patients who received surgery January 2005 July 2018. Patients were grouped according to anesthesia they received, namely desflurane or propofol. A Kaplan-Meier analysis conducted, survival curves presented from date death. Univariable multivariable Cox...

Background Previous researches have shown that anesthetic techniques may influence the patients' outcomes after cancer surgery. Here, we studied relationship between type of and following elective robot-assisted radical prostatectomy. Methods This was a retrospective cohort study patients who received elective, prostatectomy January 2008 December 2018. Patients were grouped according to anesthesia they received, namely desflurane or propofol. A Kaplan–Meier analysis conducted, survival...

Abstract Remimazolam, a gamma-aminobutyric acid subtype A receptor agonist, serves as benzodiazepine (BZD) anesthetic in monitored anesthesia care and general anesthesia. We present two cases which patients not receiving regular BZD therapy maintained consciousness following the administration of remimazolam during care. Subsequent transition to propofol infusion successfully achieved adequate sedation. Our experience indicates that efficacy may be influenced by factors other than prior use....

Background/Objectives: Anterior cervical spine surgery (ACSS) is an effective surgical procedure used to treat degenerative disease. Enhanced recovery after (ERAS) a new and promising paradigm for ACSS. The purpose of this study investigate the role neuromuscular monitoring with sugammadex in ERAS protocol, which had not been confirmed Methods: In retrospective study, electronic medical records patients aged 20 80 years who undergone first-time ACSS performed period from 1 December 2018 31...

The primary treatment for hepatocellular carcinoma (HCC) involves surgical removal of the tumor, but this creates a favorable environment proliferation and spread residual circulating cancer cells. development remimazolam-based balanced anesthesia is crucial future antitumor applications. It important to understand mechanisms cytotoxicity HCC in detail. We performed cell viability analysis, western blotting reverse transcription-polymerase chain reaction flow cytometry analysis two lines,...

This study aimed to evaluate the current status of vancomycin population pharmacokinetic modeling and assess four prediction models for predicting blood levels in patients receiving intravenous at our hospital. The goal was establish a basis personalized dosing minimize adverse reactions. retrospective analyzed treatment infections First Affiliated Hospital Shantou University Medical College from January 2021 December 2023. Patient data, including demographics specifics, were retrieved...

Surgical management of cancer may induce stress and increase the likelihood metastasis recurrence. Appropriate surgical anesthetic techniques affect patient's outcome. Although numerous studies have been performed, conflicting results obtained regarding effect on outcome patients with cancer. We conducted this study to evaluate association overall recurrence-free survival in who had undergone gastric surgery. This retrospective reviewed electronic medical records patients, visited our...

This study aimed at determining the prevalence and predictors of hypovitaminosis D (serum 25-hydroxyvitamin < 30 ng/mL) among office workers in a subtropical region from an electronic hospital database. Totally, 2880 aged 26–65 years who received health examinations with vitamin status total calcium concentrations tertiary referral center were retrospectively reviewed. Subjects divided into groups according to genders, age (i.e., 26–35, 36–45, 46–55, 56–65), body-mass index (BMI) obese...

OBJECT Anesthesia techniques can contribute to the reduction of anesthesia-controlled time and may therefore improve operating room efficiency. However, little is known about difference in between propofol-based total intravenous anesthesia (TIVA) desflurane (DES) for prolonged lumbar spine surgery under general anesthesia. METHODS A retrospective analysis was conducted using hospital databases compare lengthy (surgical > 180 minutes) patients receiving either TIVA via target-controlled...

We conducted a retrospective study to investigate the anesthesia-controlled time and factors that contribute prolonged extubation in open colorectal surgery. Using our hospital database, demographic data, various intervals (waiting for anesthesia time, surgical emergence exit from operating room after extubation, total post-anesthesia care unit stay time), incidence of (≥ 15 mins), were compared between patients who received desflurane/fentanyl-based intravenous via target-controlled...

Abstract Background: Thoracic epidural analgesia is the preferred method for postoperative following thoracic surgery. However, intravenous patient-controlled (IVPCA) may be an effective alternative. This study was conducted because few scientific reports exist comparing fentanyl-based IVPCA including a low dose of ketamine (fk-IVPCA) with (t-PCEA) treatment pain after video-assisted surgery (VATS). Methods: prospective, and randomized included 70 patients into fk-IVPCA t-PCEA groups. Pain...

Background Previous research has shown that anesthetic techniques can influence patient outcomes following cancer surgery. However, the effects of anesthesia in patients undergoing glioblastoma surgery are still not known. We studied relationship between type and elective Methods This was a retrospective cohort study who underwent January 2008 December 2018. Patients were grouped according to they received, desflurane or propofol. A Kaplan-Meier analysis conducted, survival curves presented...

// Yu-Jie Liu 1 , Ying-Cong Ma Wen-Jie Zhang Zhen-Zhen Yang De-Sheng Liang Zhi-Fu Wu 2 and Xian-Rong Qi Beijing Key Laboratory of Molecular Pharmaceutics New Drug Delivery System, School Pharmaceutical Sciences, Peking University, Beijing, 100191, PR China Materials Science Engineering, Baise Guangxi Baise, 533000, Correspondence to: Qi, email: qixr@bjmu.edu.cn Keywords: cyclopamine, temozolomide, hedgehog pathway, synergistic effect, glioma Received: January 28, 2017 Accepted: April 03,...

Abstract Background: As reported, patients experience less postoperative pain after propofol-based total intravenous anesthesia (TIVA). In the present study, we investigated analgesic effects between TIVA and desflurane spine surgery. Methods: Sixty were included who received (surgical time >180 minutes) lumbar Patients randomly assigned to receive either (with target-controlled infusion) with propofol/fentanyl-based (TIVA group) or desflurane/fentanyl-based (DES group), titrated maintain...

Breast cancer accounts for almost one quarter of all female cancers worldwide, and more than 90% those who are diagnosed with breast undergo mastectomy or conservation surgery. Local anesthetics effectively inhibit the invasion cells at concentrations that used in surgical procedures. The limited treatment options triple-negative (TNBC) demonstrate unmet clinical needs. In this study, four local anesthetics, lidocaine, levobupivacaine, bupivacaine, ropivacaine, were applied to two tumor cell...