G. Luke Machen

ORCID: 0000-0001-6391-5273
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About
Contact & Profiles
Research Areas
  • Ureteral procedures and complications
  • Kidney Stones and Urolithiasis Treatments
  • Reproductive Health and Technologies
  • Urological Disorders and Treatments
  • Pediatric Urology and Nephrology Studies
  • Male Reproductive Health Studies
  • Sperm and Testicular Function
  • Hormonal and reproductive studies
  • Reproductive Biology and Fertility
  • Sexual Differentiation and Disorders
  • Insect and Pesticide Research
  • Healthcare and Venom Research
  • Renal and Vascular Pathologies
  • Sexual function and dysfunction studies
  • Genital Health and Disease
  • Phosphodiesterase function and regulation
  • Prostate Cancer Diagnosis and Treatment
  • Anorectal Disease Treatments and Outcomes
  • Doping in Sports
  • Nail Diseases and Treatments
  • Opioid Use Disorder Treatment
  • Antifungal resistance and susceptibility
  • Metabolism, Diabetes, and Cancer
  • Adipose Tissue and Metabolism
  • Healthcare Policy and Management

Media Working Group
2021

Medical College of Wisconsin
2018-2020

Baylor Scott & White Medical Center - Temple
2017-2019

Baylor Scott & White Health
2016-2019

Memorial Sloan Kettering Cancer Center
2019

Accreditation Council for Graduate Medical Education
2019

Texas A&M Health Science Center
2017-2018

Temple College
2017

University of North Carolina at Chapel Hill
2009

Clomiphene citrate may be used as an off label treatment of hypogonadism. There are few long-term data on clomiphene efficacy and safety when administered for more than 3 years. We assessed improvements in testosterone hypogonadal symptoms while extended periods.We performed a retrospective review to identify patients treated with hypogonadism (baseline less 300 ng/dl) at total 2 institutions from 2010 2018. the duration therapy, serum levels, symptom improvement side effects.A 400 underwent...

10.1097/ju.0000000000000396 article EN The Journal of Urology 2019-06-19

To evaluate the risk of deep vein thrombosis (DVT) in men treated with testosterone replacement therapy (TRT) or Clomiphene Citrate (CC) and assess other etiologies for DVT as contributing factors.Retrospective chart review 1180 consecutive hypogonadal who were either TRT CC. Sixty-four percent had mixed, 16% primary, 20% secondary hypogonadism.Of hypogonadism, 694 TRT, while 486 Overall, 10 (0.8%) diagnosed a during treatment, 9 whom on 1 Of 7 (70%) potential identifiable than treatment...

10.1016/j.urology.2018.11.009 article EN cc-by-nc-nd Urology 2018-11-15

Cryopreservation of sperm from human semen has been available since the 1950s. The actual utilization cryopreservation technology infrequently reported. We set out to examine and outcomes cryopreserved cells based on indication for storage.A dataset was developed retrospective review. purposes cryopreservation, eventual utilization, use insemination were recorded. types accumulated as proportions different purposes. timing samples procedures evaluated using survival statistics. frequency...

10.4111/icu.2018.59.3.177 article EN cc-by-nc Investigative and Clinical Urology 2018-01-01

To examine the safety and effectiveness of use a stent with string attached after ureteroscopy (URS) for self-removal by patient.After Institutional Review Board approval, retrospective chart review was performed concerning patients who underwent URS received an indwelling or without to (94 vs 349, respectively). Amongst group single- double-arm-stringed (31 63, Statistical analyses included chi-squared Student's t-tests.The consisted 94 procedures, in which 59.6% were male mean (SD) age...

10.1016/j.aju.2018.04.005 article EN cc-by-nc-nd Arab Journal of Urology 2018-06-27

This study compared patient outcomes following irrigation applied using an automated pressure system (AP) to hand utilizing a syringe (HI) during ureteroscopy. Retrospective chart review was performed evaluate ureteroscopy procedures without ureteral access sheath. Procedures in which by AP were those with HI. Statistical analyses included chi-squared tests and Student's t tests. The group contained 206 the HI group, 25. groups 54.9% 36% male, respectively. Mean ages 53.7 ± 18.9 years 44.0...

10.1080/08998280.2018.1482518 article EN Baylor University Medical Center Proceedings 2018-10-01

When encountered, the ideal management of lithiasis in deceased donor kidneys is not well-defined. With advances endourological techniques, minimally invasive treatments are becoming an increasingly viable option. We set out to describe our experience performing ex-vivo ureteroscopy on cadaveric kidneys, including one which procedure was completed on-pump.A retrospective chart review undertaken identify patients who had undergone prior renal transplant. Four were identified, done with kidney...

10.5489/cuaj.4327 article EN Canadian Urological Association Journal 2017-08-11

We describe our management of an immunocompetent individual who developed obstructive uropathy and candidemia as a result fungal bezoar in the kidney. These sequelae arose from candiduria, provoked after several courses antibiotics. Successful treatment included therapy with both culture-appropriate intravenous antifungals operative intervention, including direct irrigation affected kidney amphotericin B, relief renal obstruction ureteral stent, percutaneous nephrostomy tube, ultimately...

10.1080/08998280.2016.11929493 article EN Baylor University Medical Center Proceedings 2016-10-01

Each year in the US, approximately 500,000 men choose to undergo a vasectomy for permanent sterilization. Despite being very common procedure, studies reporting demographic data and characteristics that motivate are somewhat limited. With this analysis, primary objective was determine if difference existed between ages number of children among choosing have at urology practices urban (Austin, TX = City A, population 947,890) rural (Temple, B, 76,277) settings. A secondary establish there...

10.21037/tau.2018.08.02 article EN cc-by-nc-nd Translational Andrology and Urology 2018-11-16

Background: To treat erectile dysfunction (ED), phosphodiesterase type 5 inhibitors (PDE5i) are commonly used. However, to date, only a few studies exist evaluate possible effect on the incidence of prostate cancer. One such study completed by authors' institution suggested men who use PDE5i for ED may have lower This was meant address some shortcomings former and further characterize link between cancer use. Methods: A retrospective, match-paired analysis undertaken: 5,717 patients were...

10.21037/tau.2017.06.02 article EN Translational Andrology and Urology 2017-10-01

You have accessJournal of UrologyStone Disease: Surgical Therapy IV1 Apr 2017PD35-08 UTILIZATION OF PRESSURIZED VS NON-PRESSURIZED IRRIGATION DURING URETEROSCOPY IN THE ABSENCE URETERAL ACCESS SHEATH: COMPARATIVE RETROSPECTIVE STUDY Karen Doersch, Amr Elmekresh, Preston A. Milburn, Graham Machen, Kyle Hart, and Marawan El Tayeb DoerschKaren Doersch More articles by this author , ElmekreshAmr Elmekresh MilburnPreston Milburn MachenGraham Machen HartKyle Hart TayebMarawan View All Author...

10.1016/j.juro.2017.02.1544 article EN The Journal of Urology 2017-04-01

You have accessJournal of UrologyInfertility: Therapy II (MP52)1 Apr 2019MP52-18 PREDNISONE AFTER VASECTOMY REVERSAL MAY IMPROVE SEMEN PARAMETERS Graham Machen* and Jay Sandlow Machen*Graham More articles by this author SandlowJay View All Author Informationhttps://doi.org/10.1097/01.JU.0000556510.80266.9aAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Although corticosteroids been...

10.1097/01.ju.0000556510.80266.9a article EN The Journal of Urology 2019-04-01

Introduction.Oncofertility is often omitted in pretreatment discussion and planning.This study seeks to evaluate the prevalence influencing factors of cryopreservation discussions.Methods.A retrospective review was performed on 3,133 male patients aged 18-60 years with a cancer diagnosis at single institution.Data collected for if sperm performed.Age, race, location, primary treatment, chemotherapy status were also recorded.Results.A total 2,504 included analysis.There documentation...

10.32371/jfp/246099 article EN Journal of Fertility Preservation 2020-01-01

You have accessJournal of UrologyInfertility: Basic Research & Pathophysiology I1 Apr 2017MP07-16 UTILIZATION RATES OF CRYOPRESERVED SPERM BASED ON THE INDICATION FOR STORAGE Graham Machen, Erin Bird, Monica Brown, Dale Ingalsbe, Milaida East, Michelle Reyes, and Thomas Kuehl MachenGraham Machen More articles by this author , BirdErin Bird BrownMonica Brown IngalsbeDale Ingalsbe EastMilaida East ReyesMichelle Reyes KuehlThomas View All Author...

10.1016/j.juro.2017.02.282 article EN The Journal of Urology 2017-04-01

You have accessJournal of UrologyStone Disease: Surgical Therapy VII1 Apr 2017MP75-02 PREDICTORS OF ED VISITS FOLLOWING URETEROSCOPY Graham Machen, Lawrence Tsai, Patrick Lowry, Erin Bird, and Marawan El Tayeb MachenGraham Machen More articles by this author , TsaiLawrence Tsai LowryPatrick Lowry BirdErin Bird TayebMarawan View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2150AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...

10.1016/j.juro.2017.02.2150 article EN The Journal of Urology 2017-04-01

You have accessJournal of UrologyStone Disease: Surgical Therapy V1 Apr 2017MP50-01 EFFECT OF DIFFERENT POSTOPERATIVE PAIN MEDICATIONS ON RETURN FOR UNPLANNED CARE AFTER URETEROSCOPY Preston Milburn, Graham Machen, Amr Elmekresh, Kristofer Wagner, Erin Bird, and Marawan El Tayeb MilburnPreston Milburn More articles by this author , MachenGraham Machen ElmekreshAmr Elmekresh WagnerKristofer Wagner BirdErin Bird TayebMarawan View All Author...

10.1016/j.juro.2017.02.1589 article EN The Journal of Urology 2017-04-01

10.1016/j.fertnstert.2018.07.469 article EN publisher-specific-oa Fertility and Sterility 2018-09-01

Over 500,000 men in America have a vasectomy annually; 2% to 6% of these individuals later elect reversal. Vasovasostomies are typically performed using single- or double-layer closure, with no demonstrated difference between the two terms success rates. In 2005, Ho et al described microscopic technique which three full-thickness sutures used and anastomosis is reinforced fibrin glue. At our institution, similar has been for >10 years. To describe experience, retrospective chart review was...

10.1080/08998280.2018.1548839 article EN Baylor University Medical Center Proceedings 2019-03-20
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