A5004402282- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Spondyloarthritis Studies and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Rheumatoid Arthritis Research and Therapies
- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Chronic Lymphocytic Leukemia Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Renal Diseases and Glomerulopathies
- Otitis Media and Relapsing Polychondritis
- Peripheral Neuropathies and Disorders
- Monoclonal and Polyclonal Antibodies Research
- Dermatology and Skin Diseases
- Pregnancy and Medication Impact
- Dupuytren's Contracture and Treatments
- Bone health and osteoporosis research
- Immune Cell Function and Interaction
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cell Adhesion Molecules Research
- Healthcare Policy and Management
- IgG4-Related and Inflammatory Diseases
- Hereditary Neurological Disorders
King Fahd Medical City
2016-2025
Alfaisal University
2024
King Saud bin Abdulaziz University for Health Sciences
2023
National Guard Health Affairs
2023
King Abdullah International Medical Research Center
2023
Prince Sattam Bin Abdulaziz University
2023
Security Forces Hospital
2023
Imam Mohammad ibn Saud Islamic University
2012-2016
Islamic University
2013
Systemic lupus erythematosus (SLE) can affect a plethora of organ systems and cause damage due to the disease process medication toxicity, notably corticosteroids. Patients with SLE often suffer irreversible damage. Older age, glucocorticoid use, longer duration, activity all represent risk factors for This study aims assess incidence predictors among Saudi Arabian patients. is single-center, retrospective cohort observational conducted at adult Rheumatology Outpatient Clinic in King Fahad...
To describe intravenous (IV) belimumab's clinical effectiveness in patients with systemic lupus erythematosus (SLE) real-world practice Saudi Arabia. This retrospective, observational OBSErve study (GSK Study 215349) analyzed medical record data for adults SLE receiving IV belimumab. Index date was the of belimumab initiation. The primary endpoint overall response per physician judgement (categorized as worse, no improvement, improvement <20%, 20-49%, 50-79%, ≥80%) at 6 months post-index....
To evaluate cost-effectiveness of upadacitinib (targeted synthetic-disease modifying anti-rheumatic drug [ts-DMARD]) as first-line (1 L) treatment versus current among patients with rheumatoid arthritis (RA) in the Kingdom Saudi Arabia (KSA), who had an inadequate response to prior conventional-synthetic (csDMARDs) and/or biologic-DMARDs (bDMARDs).
Background: Patients satisfaction is increasingly being recognized as a central element in monitoring quality of health care services; the assessment which may offer ways optimizing delivery and preventing waste medical resources. This study was designed to assess its determinants among patients attending governmental primary clinics. Methods: cross-sectional representative sample two clinics Riyadh, Saudi Arabia. Data collected via self-administered questionnaire stratified random sampling...
Abstract Psoriatic arthritis (PsA) is a complex inflammatory disease characterized by musculoskeletal and non-musculoskeletal manifestations. It distinct entity at the interface between rheumatology dermatology, making it challenging to manage. The diverse clinical presentation severity of PsA require multidisciplinary approach for optimal care. Early diagnosis management are necessary improving quality life patients. In Saudi Arabia, there currently no unified national consensus on best...
Abstract Introduction Psoriasis (PsO) is an immune-mediated chronic inflammatory disease that results in severe outcomes impact the patient’s quality of life and work productivity. We investigated effectiveness secukinumab patients with plaque psoriasis psoriatic arthritis (PsA) over a 12-month period. Methods This was longitudinal, retrospective study medical records 81 and/or who had been treated for at least 12 weeks. Results The Area Severity Index (PASI), Body Surface (BSA) percentage,...
There is increasing interest in rituximab (RTX) as an alternative to cyclophosphamide for the treatment of interstitial lung diseases (ILDs) associated with systemic sclerosis (SSc). However, no report has addressed its efficacy Saudi patients SSc-ILD. To assess RTX SSc-ILD, hospital records were reviewed between 2013 and 2016. Four female received at least 4 cycles (I cycle, consisting two infusions 1000 mg 2 weeks apart). Pulmonary function tests (PFTs) chest high-resolution computed...
Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune multi-systemic disorder of the connective tissue, characterized mainly by involvement skin, joints, kidneys, and serosal membranes. It affects females particularly at childbearing age more commonly than males. Lupus nephritis around half patients with SLE. Data about SLE in Saudi Arabia are still scarce. In this study, we aimed to evaluate prevalence, clinical laboratory findings different histological types among King...
This study aimed to assess the prevalence and determinants of osteoporosis [lumbar spine (LS) femoral neck (FN)] among patients with type 2 diabetes at King Salman Hospital.One hundred seventy were enrolled in this cross-sectional period from 1st January until July 2015. Patient selection was based on self-report previous diagnosis by a physician, being an antidiabetic agent, or fasting glucose 126 mg/dl as per American Diabetes Association criteria. A dual energy X-ray absorptiometry scan...
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease that may be associated with other disorders. To date, limited data are available on thyroid dysfunction and SLE in Saudi Arabia. In this retrospective study, we reviewed the cases of 151 patients SLE. The prevalence was 17.2%: 4% hyperthyroid group 11.9% hypothyroid group. Euthyroid sick syndrome found 1.3% patients. Moreover, 57% hypothyroidism were positive for antibodies to thyroglobulin peroxidase. No correlation...
Neuropsychiatric disorders including depression are common clinical manifestations of systemic lupus erythematosus (SLE). Depression in patients with SLE is under-recognized, although it a treatable entity. The present study aimed to determine the prevalence and identify relationship between disease characteristics.This multicenter cross-sectional was conducted rheumatology clinics four tertiary referral hospitals Saudi Arabia April September 2014. Patients' demographic data characteristics...
Cutaneous polyarteritis nodosa is a rare subtype of that lacks significant internal organ involvement. It has relapsing remitting nature and usually less responsive to conventional treatments. We report case refractory cutaneous who failed three immunosuppressive therapies different biological agents. He was successfully treated with two rituximab 1000 mg infusions good efficacy tolerance. This demonstrates the safety in treatment nodosa.
We describe a case of Immunoglobulin G4-related disease (IgG4-RD) coexisting with Behçet's disease. A 49-year-old man, diagnosis Disease for 15 years who was found to have an acute kidney injury. His investigations revealed elevated IgG4 level and the abdominal computerized tomography showed retroperitoneal mass, which diagnosed be IgG4-RD based on histology. The patient symptomatic radiological improvement after starting high dose steroid 1 month followed by maintenance dose. Our report...
Psoriasis is a chronic, inflammatory, immune-mediated skin disease that has significant impact on patient's quality of life, yet it remains challenging for dermatologists to successfully identify and manage. Without effective screening, diagnosis treatments, psoriasis can potentially progress psoriatic arthritis. A descriptive, observational cross-sectional study Saudi Arabian patients with was conducted explore dermatologist patient perspectives psoriasis, including diagnosis, management,...
To understand the most common type and clinical manifestations of associated vasculitis (AAV) in Saudi Arabia.This retrospective study was conducted at King Fahad Medical City Security Forces Hospital Program, Riyadh, Arabia, between January 2014 May 2022. Patients aged ≥18 years were included diagnosed based on manifestations, serology, or histopathology according to EMA algorithm. Univariate analysis carried out compare different groups; a series independent samples t-tests applied for...
Psoriatic arthritis (PsA) is a musculoskeletal disease that adversely affects physical mobility and quality of life. It challenging to manage because the heterogeneous nature symptoms current treatment options.To explore patient rheumatologist perspectives PsA help improve understanding experience management.A descriptive, observational cross-sectional study Saudi Arabian dermatologists rheumatologists patients with psoriasis or was conducted. Questionnaire data were collected from 31...
Objectives: Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease associated with psoriasis. In this study, we aimed to assess clinical features and the response rates various biological agents among patients PsA in Kingdom of Saudi Arabia. Materials Methods: A retrospective study where 39 diagnosed based on ClASsification criteria for period 2015–2019, were recruited from rheumatology outpatient clinics at KFMC, Riyadh, Results: Thirty-nine (31 females [79.5%] eight...