A5044825271- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Sports injuries and prevention
- Osteoarthritis Treatment and Mechanisms
- Shoulder Injury and Treatment
- Cardiovascular Effects of Exercise
- Space Exploration and Technology
- Spaceflight effects on biology
- Orthopedic Surgery and Rehabilitation
- Sports Performance and Training
- Muscle Physiology and Disorders
- Opioid Use Disorder Treatment
- Trauma Management and Diagnosis
- Lower Extremity Biomechanics and Pathologies
- Hip disorders and treatments
- Musculoskeletal pain and rehabilitation
- Advanced X-ray and CT Imaging
- Injury Epidemiology and Prevention
- Extracellular vesicles in disease
- Tendon Structure and Treatment
- Periodontal Regeneration and Treatments
- Muscle and Compartmental Disorders
- Anesthesia and Pain Management
- Pediatric Pain Management Techniques
- Traumatic Brain Injury Research
University of Alberta
2015-2025
McMaster University
2023
The Ohio State University
2015-2016
The Ohio State University Wexner Medical Center
2016
Treatment of patients with anterior cruciate ligament (ACL) injuries is often complicated by secondary damage to the meniscus and cartilage.To assess association between time from ACL tear reconstruction (ACLR) presence intra-articular at ACLR, including meniscal tears, irreparable chondral damage, knee compartment degenerative changes.Cross-sectional study; Level evidence, 3.Consecutive undergoing primary ACLR performed a single surgeon in Canadian health system over 5.5-year period were...
Abstract Background Mechanical unloading of the knee articular cartilage results in matrix atrophy, signifying osteoarthritic-inductive potential mechanical unloading. In contrast, loading stimulates production. However, little is known about response meniscal fibrocartilage, a major load-bearing tissue joint, and its functional matrix-forming fibrochondrocytes to events. Methods this study, primary meniscus isolated from inner avascular region human menisci both male female donors were...
Background. The popularity of ice hockey has grown in recent years and injuries are a concern given the physical nature sport. We sought to report rates, mechanisms, severity boys' US high school injuries. hypothesized that body checking would be major source injury concussions common. also expected find competition have higher rate than practice. Design. Descriptive epidemiology study. Methods. Boys' data from 2008/2009 through 2012/2013 academic were obtained National High School...
It is unknown whether body mass index (BMI) influences outcomes of meniscus repair. We hypothesized that increased BMI would be associated with risk failure. A retrospective study was performed involving patients who had undergone repair between 2008 and 2012. Chart review phone interviews were conducted to determine which required additional surgery. Patients categorized as normal (<25) or (≥25). Of the 305 met criteria, 216 (70.8%) available for follow-up at a mean 19 months...
Bone marrow-derived mesenchymal stem cells (BMSCs) have the potential to form mechanically responsive matrices of joint tissues, including menisci knee joint. The purpose this study is assess BMSC's engineer meniscus-like tissue relative meniscus fibrochondrocytes (MFCs). MFCs were isolated from castoffs partial meniscectomy nonosteoarthritic knees. BMSCs developed bone marrow aspirates iliac crest. All human origin. Cells cultured in type I collagen scaffolds under normoxia (21% O2) for 2...
➢ Microfracture is a treatment option for symptomatic, full-thickness cartilage defects. most likely to be successful when performed in nonobese patients under the age of thirty years small (<2 4-cm 2 ) femoral condylar defects that have been symptomatic short time (less than twelve twenty-four months). has acceptable short-term clinical results, but results can expected decline over time. Long-term studies compare microfracture with advanced restoration techniques are required ascertain...
There is a limited data on epidemiology of primary and recurrent anterior cruciate ligament reconstruction (ACLR) in Canada. The objectives this study were to examine the incidence factors associated with ACLR (revision contralateral ACLR) western Canadian province Alberta. We conducted retrospective cohort an average follow up 5.7 years. Albertans aged 10 60 years history between 2010/11 2015/16 included study. Participants followed until March 2019 observe outcomes: Ipsilateral revision...
<h3>Background:</h3> Evidence-based guidelines on the use of immobilization in management common acute soft-tissue knee injuries do not exist. Our objective was to explore practice patterns emergency physicians (EPs), sports medicine (SMPs) and orthopedic surgeons (OS) regarding early these injuries. <h3>Methods:</h3> We developed a web-based survey sent it all EPs, SMPs OS Canadian urban centre. The designed assess likelihood prescribing evaluate factors associated with from 3 disciplines...
Osteoarthritis (OA) primarily affects mechanical load-bearing joints, with the knee being most common. The prevalence, burden and severity of osteoarthritis (KOA) are disproportionately higher in females, but hormonal differences alone do not explain disproportionate incidence KOA females. Mechanical unloading by spaceflight microgravity has been implicated OA development cartilaginous tissues. However, mechanisms sex-dependent OA-like well explored. In this study, engineered meniscus...
All-inside anterior cruciate ligament reconstruction (ACLR) is an emerging technique used to treat ACL injuries. The all-inside uses a 4-stranded graft made from single tendon that looped on itself. 4 strands of the must be secured each other become closed-loop structure. Various suture configurations exist secure adjustable loop devices, and there lack data support one over another. In addition primary sutures fasten together, accessory can tied button as secondary fixation.To evaluate...
The all-inside anterior cruciate ligament reconstruction (ACLR) procedure uses a single hamstring tendon folded twice and secured to itself form 4-stranded graft. There are several possible configurations for preparing the graft.To investigate biomechanical properties of new graft preparation technique in comparison with 2 commonly used configurations.Controlled laboratory study.Five porcine flexor tendons were prepared into test configuration: side-to-side fixation backup at button loop...
Abstract Collagenase digestion (d) and cellular outgrowth (og) are the current modalities of meniscus fibrochondrocytes (MFC) isolation for bioengineering mechanobiology‐related studies. However, impact these on study outcomes is unknown. Here, we show that og‐ d‐isolated MFC have distinct proliferative capacities, transcriptomic profiles via RNA sequencing (RNAseq), extracellular matrix (ECM)‐forming, migratory capacities. Our data indicate microtissue pellet models developed from...
Background The National Hockey League (NHL) saw an unprecedented disruption to the competitive calendar due COVID-19 pandemic in March of 2020. Returning play following abrupt cessation activity is a known risk factor for athletes. Purpose To analyze occurrence and severity events (injury illness) NHL understand any differences between pre-pandemic seasons that immediately followed. Study Design Descriptive Epidemiology Methods Using retrospective cohort inclusive all players on active...
To determine whether magnetic resonance imaging (MRI) with metal artifact reduction sequencing is superior to conventional knee MRI in the evaluation of an injured anterior cruciate ligament (ACL) graft, where visualisation on can be limited by from fixation devices.Eighteen patients underwent sequence (proton density fat saturated [PDFS]) and two types (WARP, slice encoding for correction (SEMAC); Siemens) following a secondary injury their ACL reconstructed knee. Six raters experience...
Despite the ongoing opioid epidemic, most patients are still prescribed a significant number of medications for pain management after arthroscopic surgery. There is need consensus among orthopaedic surgeons and solutions to aid providers in analgesic strategies that reduce use medications.This position statement was developed with comprehensive systematic review meta-analysis exclusively randomized controlled trials (RCTs) synthesize best available evidence managing acute postoperative...
The use of particulated articular cartilage for repairing defects has been well established, but its is currently limited by the availability and short shelf life donor cartilage. Vitrification an ice-free cryopreservation technology at ultralow temperatures tissue banking. An optimized vitrification protocol developed cartilage; however, equivalency long-term clinical efficacy vitrified compared with fresh not yet determined.The repair effect from pigs would be equivalent to or better than...