- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Neurofibromatosis and Schwannoma Cases
- Liver Disease and Transplantation
- Appendicitis Diagnosis and Management
- Ultrasound in Clinical Applications
- Pediatric Hepatobiliary Diseases and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Tumors and Oncological Cases
- Congenital Diaphragmatic Hernia Studies
- Gallbladder and Bile Duct Disorders
- Ultrasound Imaging and Elastography
- Pancreatic and Hepatic Oncology Research
- Sarcoma Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Congenital Anomalies and Fetal Surgery
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound and Hyperthermia Applications
- Neuroblastoma Research and Treatments
- MRI in cancer diagnosis
- Forensic Anthropology and Bioarchaeology Studies
- Inflammatory Bowel Disease
- Fetal and Pediatric Neurological Disorders
- Histiocytic Disorders and Treatments
Ulsan College
2016-2025
University of Ulsan
2016-2025
Asan Medical Center
2016-2025
Research Institute of Radiology
2018-2024
Seoul National University Hospital
2024
Pusan National University Yangsan Hospital
2024
Seoul National University Children's Hospital
2023
Hallym University Medical Center
2022
Nassau University Medical Center
2015-2016
CHA University
2003-2004
The purpose of this study is to evaluate the accuracy and efficiency a new automatic software system for bone age assessment validate its feasibility in clinical practice.A Greulich-Pyle method-based deep-learning technique was used develop determination. Using software, estimated from left-hand radiographs 200 patients (3-17 years old) using first-rank (software only), computer-assisted (two radiologists with assistance), atlas-assisted atlas assistance only). reference determined by...
To determine the utility of intravoxel incoherent motion (IVIM)-derived perfusion and diffusion parameters for differentiation atypical primary central nervous system lymphoma (PCNSL) from glioblastoma in patients who do not have acquired immunodeficiency syndrome.The institutional review board approved this retrospective study waived informed consent requirement. Sixty with either pathologic analysis-confirmed PCNSLs (n = 19) or glioblastomas 41) were assessed by using maximum IVIM-derived...
Background Ambroxol (ABX) has been suggested as an augmentative pharmacological agent for neuronopathic Gaucher disease (nGD). This study assessed the long-term safety and efficacy of combined therapy with high-dose ABX enzyme replacement (ERT) in nGD. Methods ABX+ERT was administered 4.5 years four patients initiated at a dose 1.5 mg/kg/day, escalated up to 27 mg/kg/day. The target plasma level 10 µmol/L or less. changes glucocerebrosidase activity, biochemical, neurocognitive findings were...
Abstract Accurate risk stratification according to the extent of Langerhans cell histiocytosis (LCH) determined on whole-body evaluation is important for determining treatment plans and prognosis in patients with LCH. This study aimed compare lesion detectability accuracy skeletal survey, bone scan, magnetic resonance imaging (WB-MRI) Patients newly-diagnosed LCH who underwent all three modalities were retrospectively included (n = 46). The sensitivity mean number false-positives per patient...
To develop a deep-learning-based bone age prediction model optimized for Korean children and adolescents evaluate its feasibility by comparing it with Greulich-Pyle-based deep-learning model.A convolutional neural network was trained to predict according the development shown on hand radiograph (bone age) using 21036 radiographs of without known development-affecting diseases/conditions obtained between 1998 2019 (median [interquartile range {IQR}], 9 [7-12] years; male:female, 11794:9242)...
To establish local diagnostic reference levels (DRLs) for pediatric neck CT based on age, weight, and water-equivalent diameter (WED) across multiple university hospitals in South Korea. This retrospective study analyzed examinations from nine hospitals, involving patients aged 0-18 years. Data were categorized by WED, radiation dose metrics, including volume index (CTDI A total of 1159 analyzed, 169 scans Institution 1, 132 2, 126 3, 129 4, 128 5, 105 6, 162 7, 127 8, 81 9. Radiation...
Purpose To assess prognostic values of the POST-Treatment Extent Tumor (POSTTEXT) system and clinical factors after neoadjuvant chemotherapy in hepatoblastoma patients evaluate benefits posttreatment imaging concomitant with Children's Hepatic Tumors International Collaboration-Hepatoblastoma Stratification (CHIC-HS) system. Materials Methods This single-center retrospective study cases (2006–2022) included pediatric receiving ≥ 4 cycles chemotherapy, pre- post-treatment complete medical...
Postoperative bile duct stones, including intrahepatic (IHD) stones and remnant distal common (remnant intrapancreatic duct, RIPD) or channel (CCD) are long-term complications following choledochal cyst (CC) excision. We aimed to retrospectively review occurrence, associated factors, treatment of postoperative stones. Records 457 pediatric patients who underwent CC excision at Asan Medical Center (1992–2021) were reviewed. Data on cholelithiasis, operation, outcomes analyzed. Overall,...
The objective of this study is to evaluate patterns distant metastasis and identified factors that may increase the risk in pediatric patients with rhabdomyosarcoma.This retrospective included 69 (age, ≤ 20 years) who had rhabdomyosarcoma diagnosed between January 2000 February 2016. Various imaging features, including metastasis, were evaluated on initial follow-up studies. Differences distribution basis primary location analyzed. Logistic regression analysis was performed identify...
Purpose To develop and validate a scoring system based on clinical imaging features to predict the risk for biliary atresia in patients with neonatal cholestasis. Materials Methods Patients cholestasis who underwent both ultrasonography (US) hepatobiliary scintigraphy (n = 480) were retrospectively identified from two tertiary referral hospitals January 2000 February 2017. one hospital classified as derivation cohort 371), those other validation 109). Clinical associated assessed....
Background The validation of adult-based US risk stratification systems (RSSs) in the discrimination malignant thyroid nodules a pediatric population remains lacking. Purpose To estimate and compare diagnostic performance RSSs based on five sample. Materials methods Pediatric patients (age ≤18 years) with histopathologically confirmed US-detected at tertiary referral hospital between January 2000 April 2020 were analyzed retrospectively. US-based fine-needle aspiration biopsy (FNAB) criteria...
The MEK inhibitor, selumetinib, reduces plexiform neurofibroma (PN) in pediatric patients with neurofibromatosis type 1 (NF1). Its safety and efficacy adults PN effectiveness other NF1 manifestations (eg, neurocognitive function, growth reduction, café-au-lait spots) are unknown.
Objective: To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) in patients with infiltrative hepatocellular carcinoma (HCC) to identify prognostic factors associated patient survival.Materials Methods: Fifty two who underwent TACE for HCC were evaluated between 2007 2010.The maximum diameter tumors ranged from 7 cm 22 (median 15 cm).Of 46 portal vein tumor thrombosis, 32 received adjuvant radiation therapy thrombosis after TACE. Results:The response by...
ABSTRACT Objectives: The aim of the study was to correlate liver stiffness (LS) and hepatic venous‐pressure gradient (HVPG) evaluate diagnostic performance shear‐wave elastography (SWE) for predicting clinically significant portal hypertension in children with suspected diseases, consideration reliability criteria. Methods: We identified 33 SWEs from 32 who underwent HVPG measurement within 2 weeks between June 2012 October 2015. correlation LS assessed. (HVPG ≥ 10 mmHg) assessed using...