A5075366422- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Nuclear Physics and Applications
- Mass Spectrometry Techniques and Applications
- Astro and Planetary Science
- Atomic and Molecular Physics
- Nuclear physics research studies
- Planetary Science and Exploration
- Metal-Organic Frameworks: Synthesis and Applications
- Isotope Analysis in Ecology
- Magnetism in coordination complexes
- Ion-surface interactions and analysis
- Analytical chemistry methods development
- X-ray Spectroscopy and Fluorescence Analysis
- Radiation Detection and Scintillator Technologies
- Spacecraft and Cryogenic Technologies
- Advanced Chemical Sensor Technologies
- Identification and Quantification in Food
- Arsenic contamination and mitigation
- Pesticide Residue Analysis and Safety
- Metabolomics and Mass Spectrometry Studies
- Heavy Metal Exposure and Toxicity
- Laser-Matter Interactions and Applications
- Polyoxometalates: Synthesis and Applications
- Crystallography and molecular interactions
University of Manchester
2012-2024
Queen's University Belfast
2020
PKA-activation mechanism revised Many hormone receptors stimulate production of cyclic AMP (adenosine monophosphate), which activates PKA (protein kinase A). The textbook view suggests that activation releases the catalytic subunit enzyme from its complex with regulatory subunit. Smith et al. closely monitored in cultured human cells and found dissociation holoenzyme was not necessary for activation. kinase, binds anchoring proteins localize it cell, appears to be restricted acting within...
The thermostable four-coordinate divalent lanthanide (Ln) bis-amidinate complexes [Ln(Piso)2] (Ln = Tb, Dy; Piso {(NDipp)2CtBu}, Dipp C6H3iPr2-2,6) were prepared by the reduction of parent five-coordinate Ln(III) precursors [Ln(Piso)2I] Dy) with KC8; halide abstraction [H(SiEt3)2][B(C6F5)] gave respective [Ln(Piso)2][B(C6F5)]. All characterized X-ray diffraction, ICP-MS, elemental analysis, SQUID magnetometry, UV–vis-NIR, ATR-IR, NMR, and EPR spectroscopy ab initio CASSCF-SO calculations....
The search for materials with improved mechanical and biological properties is a major challenge in tissue engineering. This paper investigates, the first time, use of Polyethylene Terephthalate Glycol (PETG), glycol-modified class (PET), as potential material fabrication bone scaffolds. PETG scaffolds 0/90 lay-dawn pattern different pore sizes (300, 350 450 µm) were produced using filament-based extrusion additive manufacturing system mechanically biologically characterized. performance 300...
The magnetic moments and isotope shifts of the neutron-deficient francium isotopes (202-205)Fr were measured at ISOLDE-CERN with use collinear resonance ionization spectroscopy. A production-to-detection efficiency 1% was for (202)Fr. background from nonresonant collisional maintained below one ion in 10(5) beam particles. Through a comparison charge radii predictions spherical droplet model, it is concluded that ground-state wave function remains down to (205)Fr, departure observed (203)Fr (N=116).
This paper reports on the hyperfine-structure and radioactive-decay studies of neutron-deficient francium isotopes $^{202-206}$Fr performed with Collinear Resonance Ionization Spectroscopy (CRIS) experiment at ISOLDE facility, CERN. The high resolution innate to collinear laser spectroscopy is combined efficiency ion detection provide a highly-sensitive technique probe hyperfine structure exotic isotopes. decay-assisted presented, whereby isomeric beam deflected decay station for alpha-decay...
The CRIS setup at CERN-ISOLDE is a laser spectroscopy experiment dedicated to the high-resolution study of spin, hyperfine structure and isotope shift radioactive nuclei with low production rates (a few per second). It combines Doppler-free resolution in-flight collinear geometry high detection efficiency resonant ionisation. A recent commissioning campaign has demonstrated 1% experimental efficiency, as 0.001% non-resonant current status its achievements beams francium isotopes are...
The magnetic dipole moments and changes in mean-square charge radii of the neutron-rich ${}^{218m,219,229,231}\mathrm{Fr}$ isotopes were measured with newly installed Collinear Resonance Ionization Spectroscopy (CRIS) beam line at On-Line Isotope Mass Separator (ISOLDE), CERN, probing $7{s}^{2}{S}_{1/2}$ to $8{p}^{2}{P}_{3/2}$ atomic transition. $\ensuremath{\delta}{\ensuremath{\langle}{r}^{2}\ensuremath{\rangle}}^{A,221}$ values for ${}^{218m,219}\mathrm{Fr}$ ${}^{229,231}\mathrm{Fr}$...
Combination of electrospray ionization mass spectrometry (ESI-MS) and in situ atomic force microscopy (AFM) are applied to provide the first nanoscopic study crystal growth zeolitic imidazolate framework ZIF-67. ZIF-67 is found form through a process nucleation spreading metastable unenclosed substeps stable surface steps enclosed structure demonstrates that isostructural MOFs, ZIF-8, undergo identical mechanisms. The information on species obtained from AFM experiments correlates well with...
Abstract A family of heterometallic [Cat][Ti x MO (x+1 )(O 2 C t Bu) 2x+2 ] rings is reported where Cat=a secondary or tertiary alkyl ammonium ion, x=7, 8 9, and M=Fe III , Ga Cr In Al . The structures are regular polygons with eight, nine ten vertices each edge bridged by an oxide two pivalates. size the ring formed controlled alkylammonium cation present. case a homometallic by‐product found O 2x−1 ].
The routine study of the solid-water interface by XPS is potentially revolutionary as this development opens up whole new areas for photoelectron spectroscopy. To date has been realised only a few groups worldwide and current techniques have significant restrictions on type samples which can be studied. Here we present novel uniquely flexible approach to problem. By introducing thin capillary into NAP-XPS, small droplet injected onto sample surface, offset from analysis area several mm....
Abstract Identifying the form and role of chemical species that traverse stages crystallization is critical to understanding formation process coordination polymers. Herein, we report combined use in situ atomic force microscopy mass spectrometry identify preformed, complex, cadmium 2‐ethylimidazole containing solution growth 2‐ethylimidazolate metal–organic framework CdIF‐4, show they are surface nucleation for crystal this material. Surface appears be instigated by these [Cd x (CH 3 CO 2 )...
RIMSKI – Resonance Ionization Mass Spectrometer for Krypton Isotopes is a newly developed ultra sensitive instrument with cryogenic sample concentrator and laser ion source designed isotopic analysis of extraterrestrial material. Laser heating used extraction krypton from samples into the mass spectrometer volume. Atoms continuously condense on cold spot in source, are repeatedly released by heating. They ionized evaporation plume using three tunable dye lasers one frequency tripled...
Abstract 81 Kr‐Kr cosmic ray exposure ( CRE ) ages of individual chondrules (6–10 mg) and adjacent matrix samples (5–10 from the Allegan H5 chondrite have been measured using a new highly sensitive resonance ionization mass spectrometer. No conclusive evidence variations among or between has observed—average 5.90 ± 0.42 Ma Kr‐ 78 Kr) 5.04 0.37 80+82 are identical within error to those determined for (7.42 1.27 Myr, agree well with literature value bulk Allegan. If any accumulation cosmogenic...
Adulteration/unintentional contamination of milk with melamine could have negative health and economic implications especially in the developing countries due to insufficient laboratory support surveillance. This paper presents an Isotope Dilution Liquid Chromatography-Mass Spectrometry (ID LC-MS) method developed for detection powdered milk. The rapid sample preparation involved dissolution 1g powder 2.5% formic acid, precipitation protein acetonitrile, spiking samples (triamine-15N3) at...
Summary Forest soils play a pivotal role as global carbon (C) sinks, where the dynamics of soil organic matter (SOM) are significantly influenced by ectomycorrhizal (ECM) fungi. While correlations between ECM fungal community composition and C storage have been documented, underlying mechanisms behind this remain unclear. Here, we conducted controlled experiments using pure cultures growing on naturally complex SOM extracts to test how fungi regulate nitrogen (N) in response varying...
Biodegradation of citrate occurred under LLW repository relevant conditions with Ni and U present. Citrate biodegradation led to the formation insoluble sulfides or nanocrystalline U( iv )–phosphate may promote Ni/U retention in repositories.
Abstract Identifying the form and role of chemical species that traverse stages crystallization is critical to understanding formation process coordination polymers. Herein, we report combined use in situ atomic force microscopy mass spectrometry identify preformed, complex, cadmium 2‐ethylimidazole containing solution growth 2‐ethylimidazolate metal–organic framework CdIF‐4, show they are surface nucleation for crystal this material. Surface appears be instigated by these [Cd x (CH 3 CO 2 )...
A commercial MALDI mass spectrometer coupled with a tunable laser ionisation system can be used for the detection of uranium isotope ratios at trace levels.