A5036527405- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Cardiovascular Effects of Exercise
- Cardiac tumors and thrombi
- Atrial Fibrillation Management and Outcomes
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Medical Imaging and Pathology Studies
- Liver Disease and Transplantation
- Cardiovascular and exercise physiology
- Cardiovascular Disease and Adiposity
- Vascular anomalies and interventions
- Acute Ischemic Stroke Management
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Transplantation: Methods and Outcomes
- Heparin-Induced Thrombocytopenia and Thrombosis
- Vascular Anomalies and Treatments
- COVID-19 and healthcare impacts
Temple University Hospital
2016-2025
St. Joseph's Hospital and Medical Center
2025
Barrow Neurological Institute
2025
Temple University
2017-2024
Patanjali Research Foundation
2023
Pandit Deendayal Upadhyaya Shekhawati University
2023
Temple University Health System
2019-2021
Society of Thoracic Surgeons
2020
Government Medical College
2020
Presbyterian Hospital
2018
Background— Pulmonary hypertension (PH) has diverse causes with heterogeneous physiology compelling distinct management. Differentiating patients primarily elevated pulmonary vascular resistance (PVR) from those PH predominantly because of left-sided filling pressure is critical. Methods and Results— We reviewed hemodynamics, echocardiography, clinical data for 108 seen at a referral clinic transthoracic echocardiogram right heart catheterization within 1 year. derived simple...
Rationale: The aromatase inhibitor anastrozole blocks the conversion of androgens to estrogen and blunts pulmonary hypertension in animals, but its efficacy treating patients with arterial (PAH) is unknown.Objectives: We aimed determine safety PAH.Methods: performed a randomized, double-blind, placebo-controlled trial PAH who received background therapy at two centers.Measurements Main Results: A total 18 were randomized 1 mg or matching placebo 2:1 ratio. co–primary outcomes percent change...
Pulmonary heart disease (PHD) refers to altered structure or function of the right ventricle occurring in association with abnormal respiratory function. Although nearly always associated some degree PH, degree, nature, severity, and causality PH relation PHD is not necessarily linear direct. Abnormal gas exchange a fundamental underpinning PHD, affecting pulmonary vascular, cardiac, renal, neurohormonal systems. Direct indirect effects chronic can disrupt ventricular‐pulmonary arterial...
Few studies have examined the utility of serial echocardiography in evaluation, management, and prognosis patients with pulmonary arterial hypertension (PAH). Therefore, we sought to evaluate prognostic significance follow-up tricuspid annular plane systolic excursion (TAPSE) PAH. We prospectively studied 70 consecutive PAH who underwent baseline right heart catheterization (RHC) transthoracic echocardiogram, survived echocardiogram after initiation therapy. Baseline TAPSE was 1.6 ± 0.5 cm...
<h3>Background</h3> Pulmonary hypertension (PH)-targeted therapy in the setting of pulmonary fibrosis (PF) is controversial; main clinical concern worsening systemic hypoxaemia. We sought to determine effects gentle initiation and chronic administration parenteral treprostinil on right heart function patients with PF associated an advanced PH phenotype. <h3>Methods</h3> Open-label, prospective analysis PF-PH referred for lung transplantation (LT). Advanced was defined as mean artery pressure...
Summary Pulmonary embolism (PE) is a major cause of morbidity and mortality world-wide, the use thrombolytic therapy has been associated with favourable clinical outcomes in certain patient subsets. These potential benefits are counterbalanced by risk bleeding complications, most devastating which intracranial haemorrhage (ICH). We retrospectively evaluated 9703 patients from 2003–2012 nationwide in-patient sample database (NIS) who received thrombolytics for PE. All ICH during PE...
Infection with the novel severe acute respiratory syndrome coronavirus 2 has been associated a hypercoagulable state. Emerging data from China and Europe have consistently shown an increased incidence of venous thromboembolism (VTE). We aimed to identify VTE early predictors at our high-volume tertiary care center.We performed retrospective cohort study 147 patients who had admitted Temple University Hospital disease 2019 (COVID-19) April 1, 2020 27, 2020. first identified (pulmonary...
We sought to evaluate the efficacy and safety of refined balloon pulmonary angioplasty (BPA) in treatment patients with chronic thromboembolic hypertension (CTEPH).
Background: Sarcopenia, or loss of skeletal muscle mass, has been associated with poor outcomes (e.g., functional decline, increased mortality, and low quality life), but its role in CTEPH remains unclear. The psoas index (PMI) is a validated measure sarcopenia. We investigated the incidence sarcopenia using PMI CTEPH. Methods: Retrospective analysis single-center cohort patients an available computed tomography abdomen pelvis (CTAP). was measured at L3 level CTAP then calculated formula...
Abstract This study evaluates the inter- and intrarater reliability of Manjila Semaan classification system for anatomical position jugular bulb. The system, proposed in 2018, aims to address inconsistencies reporting that impact communication between radiologists skull base surgeons affect surgical planning. Bilateral bulb positions on 50 consecutive computed tomography (CT) venography examinations were assessed by two neuroradiology attending physicians, fellows, radiology residents. was...