A5073797995- Flavonoids in Medical Research
- Bone Metabolism and Diseases
- Inflammatory mediators and NSAID effects
- Sperm and Testicular Function
- Bone health and treatments
- Spine and Intervertebral Disc Pathology
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Sexual Differentiation and Disorders
Third Affiliated Hospital of Southern Medical University
2015-2021
Abstract: Osteoporosis is a systemic skeletal disease that characterized by low bone density and microarchitectural deterioration of tissue. The increasing prevalence osteoporosis has attracted much attention. In this study, MC3T3-E1 pre-osteoblasts were treated with the natural compound, baicalein (0.1 µmol/L, 1 10 µmol/L), to stimulate differentiation over 14-day period. addition, canonical ovariectomized (OVX) mouse model was used investigate effect 3-month treatment (10 mg/kg per day) in...
Mechanical stress promotes human ligamentum flavum cells (LFCs) to synthesize multitype collagens, leading hypertrophy (LFH). However, the mechanism of mechanical in formation collagen remains unclear. Therefore, we investigated relationship between and synthesis present study. First, LFCs were isolated from 9 patients cultured with or without exposure for different times. IGF-1, I (col-I), III (col-III) protein mRNA levels then detected via ELISA qPCR, respectively. Moreover, activation...