A5101817996- Fluid Dynamics and Turbulent Flows
- Advanced Numerical Methods in Computational Mathematics
- Computational Fluid Dynamics and Aerodynamics
- Magnetic and Electromagnetic Effects
- Rheology and Fluid Dynamics Studies
- Aerosol Filtration and Electrostatic Precipitation
- Dementia and Cognitive Impairment Research
- Neonatal Respiratory Health Research
- Plant and Biological Electrophysiology Studies
- Coronary Interventions and Diagnostics
- Biofield Effects and Biophysics
- Fluid Dynamics and Vibration Analysis
- Composite Material Mechanics
- Lattice Boltzmann Simulation Studies
- Bladder and Urothelial Cancer Treatments
- Suicide and Self-Harm Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Folate and B Vitamins Research
- Urinary and Genital Oncology Studies
- Elasticity and Material Modeling
- Polymer crystallization and properties
- Textile materials and evaluations
- Retinal Development and Disorders
- Clinical Nutrition and Gastroenterology
- Congenital Diaphragmatic Hernia Studies
Clemson University
2004-2023
George Washington University
2012-2021
Texas A&M University
2021
Stanford University
2006-2008
Health and Human Development (2HD) Research Network
2002-2006
National Institutes of Health
2002-2005
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2005
United States Department of Health and Human Services
2005
University of Rochester
1994-2003
University of Rochester Medical Center
1989-2001
Respiratory syncytial virus (RSV) is an increasingly recognized cause of illness in adults. Data on the epidemiology and clinical effects community-dwelling elderly persons high-risk adults can help assessing need for vaccine development.During four consecutive winters, we evaluated all respiratory illnesses prospective cohorts healthy patients (> or =65 years age) (those with chronic heart lung disease) hospitalized acute cardiopulmonary conditions. RSV infection influenza A were diagnosed...
OBJECTIVE: Existing diagnostic categories for depression may not encompass the majority of older people suffering clinically significant depressive symptoms. We have described prevalence subsyndromal symptoms and tested hypothesis that patients with greater functional disability general medical burden than nondepressed subjects but less diagnosable depressions. METHODS: Subjects were 224 patients, aged 60 years older, recruited from private internal medicine offices or a family clinic....
OBJECTIVE. Limited data suggest that psychological factors, including binge eating, dieting, and depressive symptoms, may predispose children to excessive weight gain. We investigated the relationship between baseline measures changes in body fat (measured with dual-energy x-ray absorptiometry) over time among thought be at high risk for adult obesity. METHODS. A cohort study of a convenience sample (age: 6–12 years) recruited from Washington, DC, its suburbs was performed. Subjects were...
Nitrogen dioxide (NO2) is a product of combustion that has become recognized as significant component indoor air in some homes. Despite extensive study, it remains unresolved whether exposures to low levels NO2 affect airway function or reactivity. These studies were designed assess effects various and patterns exposure on pulmonary reactivity normal humans. Normal volunteers screened for the absence hyper-reactivity exposed 3 h an environmental chamber purified NO2, separated by at least 2...
The neuropsychological performance of 18 older inpatients with major depression who were admitted following a suicide attempt was compared that 29 depressed had never attempted suicide. There an interactive effect age and group on the Trail Making Test, part B, such attempters showed greater declines age. No other differences detected between groups range tasks. These findings are discussed in context methodological limitations previous studies need for future research to better elucidate...
Cognitive dysfunction occurs in up to 65% of patients with multiple sclerosis (MS), but there is no effective treatment for the symptoms. The authors conducted a 12-week, open-pilot study assess efficacy and tolerability donepezil HCl administered MS cognitive impairment. Seventeen at long-term care facility Mini-Mental State Examination scores ≤ 25 received 5 mg 4-week period, followed by 8 weeks 10 HCl. Cognitive, neurologic, functional, behavioral assessments were baseline 4 12 weeks....
We numerically investigate spatial and temporal evolution of multiple three-dimensional vortex pairs in a curved artery model under fully developed pulsatile inflow Newtonian blood-analog fluid. discuss the connection along axial direction between regions organized vorticity observed at various cross sections model, extending previous two-dimensional analysis. human with simple, rigid 180° pipe circular section constant curvature, neglecting effects taper, torsion, elasticity. Numerical...
OBJECTIVE: A model in which cerebrovascular disease contributes to the pathogenesis of depression later life was basis authors' hypothesis that risk factors at intake are independently associated with 1-year follow-up. METHOD: The subjects were 247 patients aged 60 years or older primary care practices. study measures completed and Multiple regression techniques used determine independent association initial depressive symptoms diagnoses 1 year. RESULTS: authors found severity cumulative...
We analyzed the individual response patterns of all 121 participants who entered study. Fifty-one completed up to week 190. In 26 completers, pattern consisted an initial beneficial effect (≥6 months weight loss ≥10% from baseline) and later success (weight baseline at 160). These successful had lost 14.1 ± 1.0 kg (mean SEM); 15.9% 0.9% weight) 160 8.1 1.2 (9.1% 1.3% A second observed in 16 completers benefit partial (loss 0.1% 9.9% Other included showing only (n = 3) no 6). Seventy left:...
Effective elimination of particles deposited in the respiratory tract is an important defense function to protect organism from potentially adverse effects inhaled particles. Delivery radioactively labeled tracer and subsequent measurement vivo their retention different regions provides adequate method for characterizing this defensive function. However, delivery such by inhalation may result some external contamination animals requires specific protective measures while working with...
Low maternal folate or vitamin B12 status has been implicated in numerous pregnancy complications including spontaneous abortion. The primary aim of this study was to test a polymorphism within the trifunctional enzyme MTHFD1 (5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase) for an association with mother's risk having unexplained second trimester loss. We genotyped 125 women who had at least one abortion...
Thirty to 50% of very low-birth-weight infants have parenteral nutrition-associated cholestasis. To test the hypothesis that incidence cholestasis would be decreased if amino acids were avoided and protein given enterally, with a gestational age less than 30 weeks randomized two groups. One group received acid-free nutrition whey enterally added premature infant formula. The control standard enteral At end 3 nutrition, who had direct serum bilirubin level greater mg/dl considered significant...
OBJECTIVE: The authors' goal was to examine whether depression is associated with overreporting of functional disability. METHOD: subjects were 304 patients 60 years old or older who recruited from primary care settings. Measures included examiner ratings diagnosis and medical burden self-reported examiner-rated assessments. Multiple regression techniques used determine the independent association function after added analysis as a covariate. RESULTS: Depression poorer role functioning,...