A5101730441- Genomics and Phylogenetic Studies
- Genetic Associations and Epidemiology
- Genomics and Rare Diseases
- Cancer Genomics and Diagnostics
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- Single-cell and spatial transcriptomics
- RNA modifications and cancer
- Bioinformatics and Genomic Networks
- Gene expression and cancer classification
- Genomics and Chromatin Dynamics
- Spectroscopy and Quantum Chemical Studies
- Genetic Mapping and Diversity in Plants and Animals
- Genomic variations and chromosomal abnormalities
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Machine Learning in Bioinformatics
- CRISPR and Genetic Engineering
- Nutrition, Genetics, and Disease
- Cancer-related molecular mechanisms research
- Scientific Computing and Data Management
- Advanced Fiber Laser Technologies
- Spectroscopy Techniques in Biomedical and Chemical Research
University of California, Santa Cruz
2019-2024
Pennsylvania State University
2017
Abstract For more than two decades, the UCSC Genome Browser database (https://genome.ucsc.edu) has provided high-quality genomics data visualization and genome annotations to research community. As field of grows become available, new modes display are required accommodate technologies. New features released this past year include a Hi-C heatmap display, phased family trio for VCF files, various track improvements. Striving keep up-to-date, updates gene GENCODE Genes, NCBI RefSeq Ensembl...
Abstract The UCSC Genome Browser (https://genome.ucsc.edu) is an omics data consolidator, graphical viewer, and general bioinformatics resource that continues to serve the community as it enters its 23rd year. This year has seen emphasis in clinical data, with new tracks expanded Recommended Track Sets feature on hg38 well addition of a single cell track group. SARS-CoV-2 remain focus, regular annotation updates browser continued curation our phylogenetic sequence placing tool, hgPhyloPlace,...
The UCSC Genome Browser, https://genome.ucsc.edu, is a graphical viewer for exploring genome annotations. website provides integrated tools visualizing, comparing, analyzing, and sharing both publicly available user-generated genomic datasets. Data highlights this year include collection of easily accessible public hub assemblies on new organisms, now featuring BLAT alignment PCR capabilities, updated clinical tracks (gnomAD, DECIPHER, CADD, REVEL). We introduced Track Sets feature enhanced...
The UCSC Genome Browser (https://genome.ucsc.edu) is a web-based genomic visualization and analysis tool that serves data to over 7,000 distinct users per day worldwide. It provides annotation on thousands of genome assemblies, ranging from human SARS-CoV2. This year, we have introduced new the Human Pangenome Reference Consortium viral genomes including We added 1,200 our GenArk system, increasing overall diversity representation. support for nine user-contributed track hubs public hub...
The University of California Santa Cruz Genome Browser website (https://genome.ucsc.edu) enters its 20th year providing high-quality genomics data visualization and genome annotations to the research community. In past year, we have added a new option our web BLAT tool that allows search against all genomes, single-cell expression viewer (https://cells.ucsc.edu), 'lollipop' plot display mode for high-density variation data, RESTful API extraction custom-track backup feature. New datasets...
The UCSC Genome Browser (https://genome.ucsc.edu) is a widely utilized web-based tool for visualization and analysis of genomic data, encompassing over 4000 assemblies from diverse organisms. Since its release in 2001, it has become an essential resource genomics bioinformatics research. Annotation data available on includes both internally created maintained tracks as well custom track hubs provided by the research community. This last year's updates include 25 new annotation such gnomAD...
Abstract Interactive graphical genome browsers are essential tools in genomics, but they do not contain all the recent assemblies. We create Genome Archive (GenArk) collection of UCSC Browsers from NCBI Built on our established track hub system, this enables fast visualization annotations. Assemblies come with gene models, repeat masks, BLAT, and silico PCR. Users can add annotations via hubs custom tracks. bulk-import third-party resources, demonstrated TOGA Ensembl models for hundreds...
The UCSC Genome Browser has been an important tool for genomics and clinical genetics since the sequence of human genome was first released in 2000. As it grown scope to display more types data also complicated. data, which are dispersed at many locations worldwide, collected into one view on Browser, where graphical interface presents location. This supports expertise researcher interpret variants genome. Because analysis single nucleotide copy number require interpretation very different...
We demonstrated a molecular spectroscopic imaging method by integrating the capabilities of holography and vibrational sum frequency generation (SFG) spectroscopy. SFG is second-order nonlinear optical process that can probe vibration resonance. also poses stringent requirement noncentro-symmetry, useful for suppressing interfering contributions in complex environment. Further, holographic detection captures wide-field signal including both amplitude phase information, thus enabling new...
Interactive graphical genome browsers are essential tools for biologists working with DNA sequences. Although tens of thousands new assemblies have become available over the last decade, accessibility is limited by work involved in manually creating and curating annotations. The results can push limits data storage infrastructure. To facilitate managing this increasing number assemblies, we created Genome Archive (GenArk) collection UCSC Browsers from hosted at NCBI(1). Built on our...