A5103178816- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Circadian rhythm and melatonin
- Catalytic C–H Functionalization Methods
- Metastasis and carcinoma case studies
- Hepatitis C virus research
- Numerical methods in engineering
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Electromagnetic Scattering and Analysis
- Gastric Cancer Management and Outcomes
- Catalytic Cross-Coupling Reactions
- Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Peroxisome Proliferator-Activated Receptors
- Advanced Numerical Methods in Computational Mathematics
- Myasthenia Gravis and Thymoma
- Renal and Vascular Pathologies
- Fatigue and fracture mechanics
- Renal cell carcinoma treatment
- Matrix Theory and Algorithms
- Pediatric Hepatobiliary Diseases and Treatments
- Catalytic Alkyne Reactions
- Blood Coagulation and Thrombosis Mechanisms
Fujita Health University
2017-2024
Fujita Health University Hospital
2019-2023
Okayama Rosai Hospital
2010-2023
Josai University
2017-2021
Maruho (Japan)
2021
University of Toyama
2021
Toyo University
2014-2021
Josai International University
2006-2021
Kobe University
2011-2021
Tonami General Hospital
2011-2021
Genes expressed in hepatocellular carcinoma (HCC) were analyzed using cDNA microarrays to clarify gene abnormalities HCC. mRNA was extracted from cancerous and noncancerous tissues of 10 patients with HCC, labeled Cy5 Cy3 fluorescence prepared, it hybridized for each patient a microarray consisting 1,080 elements (930 unique genes). The expression rate element HCC evaluated the level tissue as reference. genes enhanced 2 times or more compared 5 patients. In contrast, 9 at half less tissue....
Direct C–H bond arylation of simple arenes with aryltin reagents has been successfully catalysed by PdCl2 in the presence CuCl2. CuCl2 proved to be an activator for a palladium intermediate as well oxidant.
Energy metabolism, oxygen consumption rate (VO2), and respiratory quotient (RQ) in mice were monitored continuously throughout 12:12-h light-dark cycles before, during, after time-restricted feeding (RF). Mice fed ad libitum showed robust daily rhythms both parameters: high during the dark phase low light phase. The profile of energy metabolism under daytime-only was reversed at beginning first fasting night. A few days began, RF also circadian core body temperature rhythm. Moreover, for 6...
<b>Background and aims:</b> α-Fetoprotein (AFP), a tumour marker for hepatocellular carcinoma (HCC), is associated with poor prognosis. Using cDNA microarray analysis, we previously found that ephrin-A1, an angiogenic factor, the most differentially overexpressed gene in AFP producing hepatoma cell lines. In present study, investigated significance of ephrin-A1 expression HCC. <b>Methods:</b> We examined its effect on proliferation five lines, three negative 20 human HCC specimens....
Abstract Direct C–H bond arylation of arenes with aryltrimethylsilanes catalyzed by PdCl2 in the presence CuCl2 as an oxidant has been developed. In addition to role oxidant, is found be necessary for selective cross-coupling reaction.
This study investigated the roles of thromboxane A2 (TXA2), ADP and thrombin in middle cerebral artery (MCA) thrombosis rat. The rat MCA was occluded by a thrombus induced photochemical reaction rose bengal green light that causes endothelial damage followed platelet adhesion, aggregation formation fibrin-rich at site reaction. Vapiprost, specific TXA2-receptor antagonist; clopidogrel, which has thienopyridine structure ticlopidine is more potent inhibitor ADP-induced than ticlopidine;...
We have developed a high resolution resist for laser thermal lithography and fabrication method this resist. designed material which has specific desired properties. aimed to raise the gasification temperature achieve sharply peaked profile so that holes are formed only in center of spot. were able perform with half pitch 40 nm. Furthermore, using result as dry etching mask, we on number materials, including SiO2 sapphire.
Hepatic encephalopathy (HE) is a syndrome observed in patients with liver dysfunction such as hepatitis and cirrhosis, characterized by cognitive impairment, personality changes, depressed level of consciousness. The detailed mechanism underlying the pathogenesis HE remains unclear. In present study, our aim was to establish an animal model for cirrhosis. Therefore, we carried out behavioral biochemical analysis cirrhotic rats after treatment thioacetamide (TAA) 20 weeks. subjected chronic...
Ischemic cerebral infarcts induce hypercoagulation and microthrombosis in the surrounding region, thus leading to vascular occlusion. We determined whether microthrombi contribute spreading of ischemic lesions following thrombotic middle artery (MCA) occlusion also argatroban, a selective thrombin inhibitor, reduces formation area lesions. The rat left MCA was occluded by platelet-rich thrombus formed photochemical reaction between rose bengal green light. Microthrombi were histologically...
The application of methionine on wounded rice leaves induced the production phytoalexins, sakuranetin and momilactone A. This induction resulted from stimulation phenylalanine ammonia-lyase naringenin 7-O-methyltransferase activity. Jasmonic acid, ethylene, active oxygen species are important as signal transducers in disease resistance mechanisms. However, although endogenous level jasmonic acid rapidly increased reaction to wound, treatment could not JA production. Ethylene flavonoid...
FOLFIRINOX (FFX) and gemcitabine (GEM) plus nab-paclitaxel (GnP) have recently been available for treating pancreatic ductal adenocarcinoma (PDAC). We investigated trends in characteristics, treatment outcomes of unselected patients with unresectable PDAC real-life practice Japan. retrospectively reviewed the medical records 1085 diagnosed as having or recurrent multiple centers Hokuriku area between January 2009 July 2015. The incidence pathologically proven had increased from 18.7% to...
Estimation of liver damage is important in the pathophysiological and toxicological study disease. As a novel, non-invasive marker damage, we studied efficacy urine bile acids (UBA) rat model Thioacetamide (TAA)-treated rats were used this study. Single intraperitoneal administration high-dose TAA induces severe to liver, thus as acute hepatitis. Continuous low-dose yields mild cirrhosis hepatic tumors. In study, it was found that both chronic associated with dose-dependent elevation UBA....
Abstract OBJECTIVES The aim of the present study was to examine some initial results and learning curves concerning subxiphoid single-port thymectomy (SSPT), thereby clarifying safety this surgical approach describing precautions for adopting it. METHODS From March 2011 August 2019, a total 203 patients underwent either anterior mediastinal tumours or myasthenia gravis at Fujita Health University Hospital. Of these patients, 147 who had undergone SSPT were selected as participants study....