A CHANGE in the concepts regarding idiopathic thrombocytopenic purpura has occurred during past fifteen years mainly because of recognition three important facts: The thrombocytopenia is result increased platelet destruction. old hypothesis, originally postulated by Frank,1 , 2 a toxic depression megakaryocytes and their activity resulting been disproved since shortened life-span regularly found disease. An antiplatelet factor with characteristics an antibody present plasma these patients.3...

The nature of the platelet response to osmotic shock and its relationship viability were studied. Light absorbancy changes human concentrates exposed hypotonic measured in a spectrophotometer: sudden drop light was followed by reversal towards normal (reversal reaction). It confirmed that reaction is complex phenomenon dependent on integrity biochemical enzymatic functions platelets. suppressed glycolytic inhibitors SH‐blocking agents. Ouabain had no immediate effect, but with prolonged...

✓ Four patients with tentorial arteriovenous malformations (AVM's) were treated surgically. The operative findings in the first case suggested that clipping of draining vein close to AVM may result complete cure. three subsequent cases this technique. clinical and radiological implications are discussed.

Sialic acid has been demonstrated in the blood platelets of man and other species (1, 2), but its function these elements is unknown.Jeru- shalmy, Kohn, de Vries (3) others (4, 5) have shown that Myxoviruses are adsorbed to eluted from platelets.Bacterial neur- aminidase, which liberates free sialic by cleavage a-ketosidic linkage between ter- minal galactose or galactosamine (6), interferes with platelet adsorptionelution phenomena a manner qualitatively similar effect on erythrocytes (7)...

Given the growing interest in multipurpose hemp crop, eight monoecious cultivars were compared a two-year trial for quantitative and qualitative yield Mediterranean environment characterized by temperate humid climate with hot summers. All evaluated potential of (i) seed plus stem at maturity, (ii) essential oil from inflorescences harvested full flowering. The second goal was set to test ability supply new seeds after removal inflorescence Among cultivars, Fedora obtained best results (0.79...

Walnut oil use is currently limited by its poor oxidative stability due to the high percentage of polyunsaturated fatty acids. Modifying composition may be a goal in walnut breeding increase interest this crop. Exploring natural variability and identifying main environmental factors affecting quality are necessary crop selection. Therefore 190 wild accessions were collected evaluated during 2013 2014 for content acid profile compared with five commercial cultivars as references.High...

Summary The thrombocytopenia in patients with the Wiskott‐Aldrich syndrome was found to be due increased platelet destruction caused by an intracorpuscular cell defect. Multiple abnormalities of structure, function, and metabolism were also observed. Platelet adhesiveness collagen, aggregation ADP, epinephrine reduced or absent affected partially depressed clinically normal female carrier. Of various biochemical alterations, decrease glycogen hexokinase activity most prominent. latter defect...

A 100-nanosecond pulse of long-wavelength x-rays was used to produce high-resolution stop-motion images living human platelets. Although some aspects the structure conform those seen in dehydrated specimens, novel features are apparent. The technique should permit detailed examination interaction platelets with their surrounding medium as well exploration phagocytic and secretory activities a wide variety other cells.

The in vitro biphasic reaction of platelets to hypotonic stress measured a spectrophotometer (reversal reaction) was used as an indicator platelet integrity series experiments on preservation human by freezing. Following these results guideline, were cooled at 1° per min −35° using 5% DMSO plasma the cryoprotective agent. Addition and removal done very gradually minimize osmotic stress. Survival studies after labeling with radioactive sodium chromate demonstrated nearly normal viability...

Biochemistry, function, and hemostatic effectiveness of human platelets preserved by freezing with 5% DMSO (1, 2) were studied. Determination platelet glycogen, β-glucuronidase (a lysosomal enzyme), purine nucleoside phosphorylase cytoplasmic enzyme) showed that thawing caused a complex cell lesion. Hemostatic the frozen was measured from shortening bleeding time (template method) upon infusion in patients severe stable thrombocytopenia due to bone marrow depression. The produced degree...