- Meat and Animal Product Quality
- Stress Responses and Cortisol
- Animal Nutrition and Physiology
- Neuroendocrine regulation and behavior
- Ruminant Nutrition and Digestive Physiology
- Bee Products Chemical Analysis
- Genetic and phenotypic traits in livestock
- Adipose Tissue and Metabolism
- Hormonal Regulation and Hypertension
- Muscle metabolism and nutrition
- Microbial Inactivation Methods
- Regulation of Appetite and Obesity
- Nuclear Structure and Function
- Muscle Physiology and Disorders
- Animal Behavior and Welfare Studies
- Animal Genetics and Reproduction
- Pharmacological Effects and Assays
- Tryptophan and brain disorders
- CRISPR and Genetic Engineering
- Listeria monocytogenes in Food Safety
- RNA Research and Splicing
- Fatty Acid Research and Health
- Estrogen and related hormone effects
- Insect Utilization and Effects
- Adrenal Hormones and Disorders
University of Minnesota
2024-2025
University of Cincinnati
2014-2023
University of Cincinnati Medical Center
2010-2022
University of Maiduguri
2020
Georgia State University
2003-2015
National Human Genome Research Institute
2015
Beltsville Agricultural Research Center
1998-2013
Agricultural Research Service
2001-2013
Haramaya University
2013
United States Department of Agriculture
1986-2010
Individuals often eat calorically dense, highly palatable “comfort” foods during stress for relief. This article demonstrates that food intake (limited of sucrose drink) reduces neuroendocrine, cardiovascular, and behavioral responses to in rats. Artificially sweetened (saccharin) drink reproduces the dampening, whereas oral intragastric gavage is without effect. Together, these results suggest palatable/rewarding properties are necessary sufficient dampening. In support this finding,...
Abstract Adolescent development is proposed to represent a time of increased susceptibility stress. During adolescence, the brain demonstrates high level plasticity and can be positively or negatively affected by environment. This study tests hypothesis that adolescent stage enhanced vulnerability chronic Male Sprague-Dawley rats were exposed our 14-d variable stress (CVS) paradigm at three developmental stages: 1) early adolescence (35 d; age initiation CVS); 2) late (50 d); 3) adulthood...
Thirty-six barrows were used in a 2 X 3 factorial experiment to investigate the effects of porcine growth hormone (pGH) administration (USDA-pGH-B1; 0 and 100 micrograms.kg body weight-1.d-1) three levels feeding single diet (EI; ad libitum, 1.64 1.38 kg/d) on performance, composition rates protein fat deposition pigs growing over live weight phase 25 55 kg. Raising EI resulted linear increases rate accretion but had no effect feed gain ratio (F/G). Carcass content carcass measurements also...
Forty-five pigs with an average initial live weight of 60 kg were used to investigate the effects daily exogenous porcine pituitary growth hormone administration at two dose levels (pGH; 0, excipient buffer injected, and 100 micrograms.kg-1.d-1) for a 31-d period on performance body composition boars, gilts barrows allowed consume feed ad libitum. Excipient boars consumed less feed, exhibited faster more efficient (P than .01) produced fat protein water in empty compared barrows, which turn...
Overeating and increases in body fat mass are the most common responses to day-to-day stress humans, whereas stressed laboratory rats mice respond oppositely. Group housing of Syrian hamsters mass, adiposity, food intake, perhaps due social confrontation-induced stress. In experiment 1 we asked, Does repeated defeat increase white adipose tissue (WAT) hamsters? Male subjected resident-intruder interaction model defeated intermittently 15 times over 34 days for 7-min sessions significantly...
Abstract Chronic stress induces presynaptic and postsynaptic modifications in the paraventricular nucleus of hypothalamus that are consistent with enhanced excitatory hypothalamo‐pituitary‐adrenocortical (HPA) axis drive. The brain regions mediating these molecular not known. We hypothesized chronic variable (CVS) tonically activates stress‐excitatory interact hypothalamus, culminating facilitation. In order to identify chronically activated regions, ΔFosB, a documented marker tonic neuronal...
Glucocorticoids act rapidly at the paraventricular nucleus (PVN) to inhibit stress-excitatory neurons and limit excessive glucocorticoid secretion. The signaling mechanism underlying rapid feedback inhibition remains be determined. present study was designed test hypothesis that canonical receptors (GRs) is required for appropriate hypothalamic-pituitary-adrenal (HPA) axis regulation. Local PVN GR knockdown (KD) achieved by breeding homozygous floxed mice with Sim1-cre recombinase transgenic...
Life stress frequently occurs within the context of homeostatic challenge, requiring integration physiological and psychological need into appropriate hormonal, cardiovascular, behavioral responses. To test neural mechanisms underlying adversity, we evaluated impact a pronounced (hypernatremia) challenge on hypothalamic-pituitary-adrenal (HPA), responses to an acute psychogenic stress. Relative normonatremic controls, rats rendered mildly hypernatremic had decreased HPA activation in...
An emerging literature attests to the ability of psychological stress alter inflammatory cytokine environment body. While cause release is well established, neural pathways involved in this control have yet be identified. This study tests hypothesis that IL-6 neurons hypothalamo-neurohypophyseal system (HNS), a pathway proposed secrete into circulation, are activated response stress. Colocalization studies confirm robust expression cell bodies and fibers vasopressin (but not oxytocin)...
Abstract Chronic variable stress ( CVS ) exposure modifies the paraventricular nucleus of hypothalamus PVN in a manner consistent with enhanced central drive hypothalamo‐pituitary‐adrenocortical (HPA) axis. As previous reports suggest that post‐stress enhancement norepinephrine NE action contributes to chronic regulation at level , we hypothesised ‐projecting neurons were necessary for facilitatory effects . Following intra‐ injection saporin toxin conjugated dopamine beta‐hydroxylase DBH...
The amounts of 14 conjugated linoleic acid (CLA) isomers (t12t14, t11t13, t10t12, t9t11, t8t10, t7t9, t6t8; 12,14 c/t, t11c13, c11t13, t10c12, 9,11 t8c10, t7c9-18:2) in 20 beef samples were determined by triple-column silver-ion high-performance liquid chromatography (Ag+-HPLC). Quantitation was performed using an external CLA reference standard consisting cis9,trans11-18:2,trans9,trans11-18:2 and cis9,cis11-18: 2. Linearity checked as being r > 0.9999 between 0.02 × 10-3 to 2 mg/ml....
The organoleptic trait most affecting consumer acceptance of beef is tenderness. Hydrodyne process uses a small amount explosive to generate shock wave in water. passes through (in fractions millisecond) objects the water that are an acoustic match with Four muscles (longissimus, semimembranosus, biceps femoris, and semitendinosus) exposed either 50, 75, or 100 g explosives were significantly tenderized compared controls. As much as 72% reduction shear force was observed for longissimus...