A5077359410- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Lung Cancer Research Studies
- Cardiovascular Function and Risk Factors
- Inhalation and Respiratory Drug Delivery
- Genetic Mapping and Diversity in Plants and Animals
- Cardiomyopathy and Myosin Studies
- Neonatal Respiratory Health Research
- Microtubule and mitosis dynamics
- Fibroblast Growth Factor Research
- Viral Infectious Diseases and Gene Expression in Insects
- Health Systems, Economic Evaluations, Quality of Life
- Medical Imaging and Pathology Studies
Cincinnati Children's Hospital Medical Center
2019-2021
Australian National University
2021
University of Cincinnati Medical Center
2021
Pulmonary Associates
2021
Canberra Hospital
2021
Miami University
2017
Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease associated with unremitting fibroblast activation including fibroblast-to-myofibroblast transformation (FMT), migration, resistance to apoptotic clearance, and excessive deposition of extracellular matrix (ECM) proteins in the distal parenchyma. Aberrant lung-developmental pathways severe disease; however, mechanisms through which these activate fibroblasts IPF remain unclear. Sry-box transcription factor 9 (Sox9) member...
Article6 August 2020Open Access Source DataTransparent process Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis Rajesh K Kasam Division Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA Department Biochemistry, National Institute Nutrition, Hyderabad, India Search for more papers by this author Sudhir Ghandikota orcid.org/0000-0003-3996-992X Biomedical Informatics, Computer Science, University College Engineering,...