- Cephalopods and Marine Biology
- Neurobiology and Insect Physiology Research
- Chemical synthesis and alkaloids
- Veterinary Pharmacology and Anesthesia
- Plant and Biological Electrophysiology Studies
- Multiple Sclerosis Research Studies
- Botanical Research and Applications
- Cytokine Signaling Pathways and Interactions
- Physiological and biochemical adaptations
- Extracellular vesicles in disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Plant and animal studies
- Autophagy in Disease and Therapy
- Photoreceptor and optogenetics research
- Immune Cell Function and Interaction
- Animal and Plant Science Education
Universidad Nacional Autónoma de México
2015-2024
University of Chile
2024
Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and proteins. Impaired autophagic activity involved in number diseases, including idiopathic pulmonary fibrosis suggesting altered autophagy may contribute to fibrogenesis. However, specific role lung still undefined. In this study, we show for first time, how disruption contributes bleomycin-induced vivo using an Atg4b-deficient mouse as model. mice displayed significantly higher...
The Novel Object Recognition task (NOR) is widely used to study vertebrates' memory. It has been proposed as an adequate model for studying memory in different taxonomic groups, allowing similar and comparable results. Although cephalopods, several research reports could indicate that they recognize objects their environment, it not tested experimental paradigm allows phases. This shows two-month-old older Octopus maya subjects can differentiate between a new object known one, but...
Electrophysiology in plants is understudied, and, moreover, an ideal model for student inclusion at all levels of education. Here, we report on investigation open science, whereby scientists worked with high school students, faculty, and undergraduates from Chile, Germany, Serbia, South Korea, the USA. The students recorded electrophysiological signals >15 plant species response to a flame or tactile stimulus applied leaves. We observed that approximately 60% studied showed response, delay ~...
Cumulative evidence has established that Interferon (IFN)-γ both pathogenic and protective roles in Multiple Sclerosis the animal model, Experimental Autoimmune Encephalomyelitis (EAE). However, underlying mechanisms to beneficial effects of IFN-γ are not well understood. In this study, we found exerts therapeutic on chronic, relapsing-remitting, chronic progressive EAE models. The frequency regulatory T (Treg) cells spinal cords from mice treated with was significantly increased no effect...
ABSTRACT The role of nitric oxide as a neurotransmitter in the olfactory and chemoreception systems invertebrates has been well documented. This suggests an early efficient sensory detection system that is evolutionarily preserved various species, including vertebrates invertebrates. Additionally, presence reported molluscs, particularly octopus species. In this work, we present evidence for existence synthase neurons fibers, its anatomical localization nuclei involved chemosensory...
ABSTRACT Behavioral studies have predominantly focused on organisms within the phyla Craniata and Arthropoda. Yet, there has been a growing interest in studying behavior of from alternative phyla, such as mollusks, owing to research opportunities they offer. Among cephalopods emerged prominent subject inquiry. However, behavioral Mexico’s endemic species, Octopus maya (Om) , remains conspicuously scarce. Om exhibits favorable attributes for utilization standardized animal model neuroscience...
Abstract The Novel Object Recognition task (NOR) is widely used for the study of memory in vertebrates and has been proposed as a solid candidate evaluating different taxonomic groups, allowing similar comparable evaluations between them. Although, cephalopods, several research reports could indicate that they recognize objects their environment, so far, it not evaluated an experimental paradigm, which allows phases memory. In this study, we show Octopus maya can differentiate new object...
Abstract Octopuses show a wide behavioral range that allows them great adaptability to their environment this has permitted be the target of interest for biophysics, cytology, and neurobiology studies. To adequately execute these investigations, it is essential have thorough understanding neuroanatomy species function as good laboratory models, example, O. Maya. In work, we undertake task extracting characterizing various structures nervous system Maya at level lobes connectivity between...
ABSTRACT Historically, behavior studies have focused mainly on animals of two phyla in particular: Craniata and Arthropoda, however, behavioral research alternative like mollusks has been increasing because the potential for that these models present. When we talk about mollusk behavior, cephalopods are first group stands out, Mexico’s endemic species Octopus maya , is still lacking. This octopus could help to reach a standardized model neuroscience, adapts well laboratory conditions...
Abstract Electrophysiology in plants is understudied, and, moreover, an ideal model for student inclusion at all levels of education. Here we report on investigation “open science”, whereby scientists worked with students and faculty from Chile, Germany, Serbia, South Korea, the USA. The recorded electrophysiological signals >15 response to a flame or tactile stimulus applied leaves. We observed that approximately 60% studied showed delay ∼3-6 seconds after presentation. In preliminary...