A5084234763- Advanced Polymer Synthesis and Characterization
- Hydrogels: synthesis, properties, applications
- Surfactants and Colloidal Systems
- Nanoparticle-Based Drug Delivery
- Polymer Surface Interaction Studies
- Electrostatics and Colloid Interactions
- biodegradable polymer synthesis and properties
- Microfluidic and Capillary Electrophoresis Applications
- Characterization and Applications of Magnetic Nanoparticles
- Pickering emulsions and particle stabilization
- Photopolymerization techniques and applications
- Electrowetting and Microfluidic Technologies
- Polymer Nanocomposites and Properties
- Micro and Nano Robotics
- Advanced Drug Delivery Systems
- Mesoporous Materials and Catalysis
- Iron oxide chemistry and applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microplastics and Plastic Pollution
- Antimicrobial agents and applications
- Polymer Science and PVC
- Advanced Biosensing Techniques and Applications
- Monoclonal and Polyclonal Antibodies Research
- Lipid Membrane Structure and Behavior
- Advanced Materials and Mechanics
University of the Basque Country
2010-2019
Polymat
2005-2014
UFI Filters (Italy)
2014
Laboratoire de Chimie des Polymères Organiques
1998-2002
École Nationale Supérieure de Chimie, de Biologie et de Physique
2001
Universidad de Granada
1998
Universidad de Málaga
1998
University of Almería
1998
Centre National de la Recherche Scientifique
1998
In this work, the classical theory of polymer/polyelectrolyte gel swelling is reviewed. This formalism easy to understand and has been widely applied gels microgel particles. Nevertheless, its limitations obscure aspects should be known before use. The case temperature-sensitive discussed in some detail because it deserves particular clarification. application experimental data (of both microgels) also way, strengths weaknesses approach can elucidated. Moreover, other formalisms are...
Poly(N-isopropylacrylamide) (PNIPAM) and poly(N-vinylcaprolactam) (PVCL) are temperature-responsive polymers which show a lower critical solution temperature (LCST) around 32 °C in aqueous solutions. Nanogels based on these sensitive swell at low temperatures collapse high ones, showing volume phase transition (VPTT) near physiological temperature. This unique behavior makes nanogels attractive for biotechnological applications. PNIPAM is the building block of huge amount reported...
Abstract Three types of poly( N ‐vinylcaprolactam)‐based temperature‐sensitive microgel particles were synthesized by emulsion polymerization. The uptake a model drug (calcein) into the was analyzed in terms amount calcein absorbed and equilibrium–swelling degree. By incubating microgels with primary neuronal cell cultures embrionary rats, viability biocompatibility tests carried out. results show that driving force for to penetrate is H‐bonding associations. On other hand, death...
The use of nanotechnology in biotechnological applications has attracted tremendous attention from researchers. Currently many nanomaterials, such as soft nanoparticles, are under investigation and development for their biomedicine. Among polymeric gels the nanometre range, known nanogel particles, have received considerable attention. Nanogel which formed by chains loosely cross-linked to form a three-dimensional network, swell thermodynamically good solvent but do not dissolve it. Nanogels...
Abstract A water‐based magnetite ferrofluid, with an average size of about 10 nm, was prepared in a first step by the chemical coprecipitation ferrous and ferric salts. Oil‐based styrene (St) ferrofluid obtained acidification dispersion acidified St. Magnetic polymeric composite particles (MPCPs) were miniemulsion polymerization presence oil‐based St hexadecane as hydrophobe, 2,2′‐azobisisobutyronitrile initiator, sodium dodecyl sulfate emulsifier. Methacrylic acid used comonomer,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMiniemulsion Polymerization Using Oil-Soluble InitiatorsJuan A. Alduncin, Jacqueline Forcada, and Jose M. AsuaCite this: Macromolecules 1994, 27, 8, 2256–2261Publication Date (Print):April 1, 1994Publication History Published online1 May 2002Published inissue 1 April 1994https://pubs.acs.org/doi/10.1021/ma00086a041https://doi.org/10.1021/ma00086a041research-articleACS PublicationsRequest reuse permissionsArticle Views773Altmetric-Citations97LEARN...
Abstract Poly( N ‐vinylcaprolactam) (PVCL) is well known for its thermoresponsive behavior in aqueous solutions. PVCL combines useful and important properties; it biocompatible polymer with the phase transition region of physiological temperature (32–38 °C). This combination properties allows consideration as a material design biomedical devices use drug delivery systems. In this work, based temperature‐sensitive crosslinked particles (microgels) were synthesized batch reactor to analyze...
Self-stabilized magnetic polymeric composite nanoparticles (SS-MPCPs) were prepared by emulsifier-free miniemulsion polymerization using styrene (St) as a monomer, sodium p-styrenesulfonate (NaSS) an ionic comonomer, hexadecane (HD) hydrophobe, and 2,2'-azodiisobutyronitrile (AIBN) initiator in the presence of hydrophobic magnetite particles. The particles with average size about 10 nm acidification water-based ferrofluid, previously synthesized chemical coprecipitation method. Some...
Abstract New microgel particles produced by using N ‐vinylcaprolactam (VCL) and poly(ethylene glycol) diacrylate (PEGDA) or , ′‐methylenbisacrylamide (BA) were synthesized in a batch reactor. The influence of the concentration type crosslinker on polymerization kinetics colloidal characteristics such temperature‐sensitive was studied. partial total conversion evolutions VCL, PEGDA, BA determined quantitative 1 H NMR average diameters together with swelling–deswelling behavior analyzed means...
In this work, a quantitative comparison between experimental swelling data of thermo-sensitive microgels and computer simulation results obtained from coarse-grained model polyelectrolyte network the primitive electrolyte is carried out. Polymer-polymer hydrophobic forces are considered in through solvent-mediated interaction potential whose depth increases with temperature. The qualitative agreement experiment very good. particular, our simulations predict gradual shrinkage temperature,...
Abstract Two different synthesis strategies were used to synthesize N ‐vinylcaprolactam (VCL)‐acrylic acid (AA)‐based temperature‐ and pH‐sensitive microgels under the adequate conditions avoid possible hydrolysis of VCL due presence carboxylic groups provided by AA. Polymeric colloidal features analyzed: partial conversion evolutions each comonomer determined 1 H NMR swelling/deswelling behavior means Photon Correlation Spectroscopy. Considering that are porous soft nanoparticles,...
Due to the existing interest in new hybrid particles colloidal range based on both magnetic and polymeric materials for applications biotechnological fields, this work is focused preparation of polymer nanoparticles (MPNPs) by a single-step miniemulsion process developed achieve better control morphology nanocomposite particles. MPNPs are prepared surfactant-free polymerization using styrene (St) as monomer, hexadecane (HD) hydrophobe, potassium persulfate (KPS) an initiator presence oleic...
Two new families of thermo-responsive and enzymatically degradable nanogels were synthesized by batch emulsion polymerization N-vinylcaprolactam (VCL) with dextran methacrylates (Dex-MA) different degrees substitution (DS). The first family was prepared using amounts Dex-MA high DS forming highly cross-linked nanogel particles the typical thermal behavior PVCL-based nanogels: below volume phase transition temperature (VPTT) swollen above it they collapsed. After their enzymatic degradation...
The tunable structure of silica–latex nanocomposites made silica nanoparticles (radius ≈ 80 Å) and a copolymer methyl methacrylate butyl acrylate–latex beads 210 has been studied by small-angle neutron scattering transmission electron microscopy. An aggregation diagram as function the control parameters—silica volume fraction precursor solution pH—has established. In this diagram, isoaggregation lines have identified. It was used to express small-strain reinforcement factor measured with...
Dual‐stimuli‐responsive nanogel particles based on poly(2‐(diethylamino)ethyl) methacrylate (PDEAEMA) cross‐linked with ethylene glycol dimethacrylate (EGDMA) are prepared via batch emulsion polymerization. An in‐depth study of their swelling behavior is carried out, which presents a dual‐dependent thermo‐ and pH‐sensitivity tunable the ionic strength. The reveals that undergo unique transition from swollen state to collapsed at physiological conditions. Such systems presenting sensitivity...
ABSTRACT Herein, the synthesis and potential application as cargo delivery systems of thermo‐responsive poly( N ‐vinylcaprolactam) (PVCL)‐based, pH‐responsive poly(2‐(diethylamino)ethyl) methacrylate (PDEAEMA)‐based, thermo‐, PDEAEMA/PVCL‐based core–shell nanogels are reported. All have been synthesized using different dextran‐methacrylates (Dex‐MAs) macro‐cross‐linkers. Doxorubicin hydrochloride (DOXO), an anticancer drug, has effectively loaded into via hydrogen‐bonding interactions...
Abstract The effect of the monomer/water ratio on rate polymerization per polymer particle in both seeded emulsion polymerizations and miniemulsion was used an attempt to elucidate main locus radical formation initiated by oil‐soluble initiator (AIBN). It found that, for rest conditions constant, increased when increased, namely amount dissolved aqueous phase decreased. This is evidence against a dominant radicals. On other hand, these results are consistent with mechanism which radicals...
Abstract A mathematical model for the unseeded emulsion copolymerization of styrene and methyl methacrylate has been developed. This model, which includes a new rate coefficient radical desorption, was used to analyze effect styrene/methyl molar ratio in initial charge on number particles, overall conversion copolymer composition. It found that particles increased with content drift composition resulted during polymerization ratios other than 50/50. Good agreement between experimental...
Abstract Hybrid silica/polystyrene nanoparticles were synthesized by miniemulsion polymerization. With the objective to prepare core‐shell hybrid having narrow particle size distributions (PSDs) as well a high degree of silica encapsulation, effect adding surface modifiers, nanoparticles, ratio styrene/silica, surfactant concentration, and presence ethanol in reaction mixture studied. A synergistic was observed using oleic acid (OA) together with 3‐(trimethoxysilyl)propyl methacrylate (TPM)...