The goal of neuromorphic engineering is to build electronic systems that mimic the ability brain perform fuzzy, fault-tolerant, and stochastic computation, without sacrificing either its space or power efficiency. In this paper, we determine operating characteristics novel nanoscale devices could be used fabricate such systems. We also compare performance metrics a million neuron learning system based on these with an equivalent implementation entirely end-of-scaling digital CMOS technology...

Abstract Cuproptosis, a kind of newly recognized cell death modality, shows enormous prospect in cancer treatment. The inducer cuproptosis has more advantages tumor therapy, especially that can trigger and chemodynamic therapy (CDT) simultaneously. However, is restricted to the deficiency intracellular copper ions nonspecific delivery copper‐based ionophores. Therefore, high level delivery, responsive release, utilizing synergistic‐function become key on cuproptosis‐based oncotherapy. In...

Photothermal therapy (PTT) is hampered by the limited capacity of light penetration, non-specific thermal diffusion damage to surrounding healthy tissues, and thermoresistance originating in heat shock proteins (HSPs). Here, a triple-respondent (triphosphate, glutathione, pH) cascade nanoreactor was designed through glucose consumption-induced sensitization strategy. The near-infrared-II (NIR-II) photothermal reagent Bi–Au encapsulated oxidase-based protein–polyphenol structure with help...

Cuproptosis exhibits enormous application prospects in treatment. However, cuproptosis-based therapy is impeded by the limited intracellular copper ions, nonspecific delivery, uncontrollable release, and chelation of endogenous overproduced glutathione (GSH). In this work, an ultrasound-triggered nanosonosensitizer (p-TiO2–Cu(I)) was constructed for Cu(I) on-demand GSH consumption, deeper tissue response. When nanomedicine internalized into tumor cells, ultrasound (US) induced to produce...

The key to fault diagnosis of rotating machinery is extract features effectively and select the appropriate classification algorithm. As a common signal decomposition method, effect wavelet packet (WPD) largely depends on applicability basis function (WBF). In this paper, novel approach for based feature importance ranking selection proposed. Firstly, two‐step principle proposed most suitable WBF vibration signal, which an optimized WPD (OWPD) method decompose information in frequency...

摘要: 由于超声振动复合加工过程很难通过动力学分析得到有效的切割机理的数学模型,而试验研究不失为解决该问题的一种有效方法。采用中心复合设计(Central composite design,CCD)试验方法,设计四因素三水平的SiC单晶片超声振动复合加工试验方案;引入响应曲面法建立切向锯切力、表面粗糙度与主要工艺参数(线锯速度、工件进给速度、工件转速和超声波振幅)的二阶关系模型,通过对试验数据的多元二次拟合,分别获得切削力和表面粗糙度的二次方程表达式;进一步分析实际加工条件对工艺参数的约束,并以提高SiC单晶片表面的加工质量(即最小化加工表面粗糙度)为目标建立工艺参数优化模型;设计粒子群优化算法及其流程进行优化问题求解,通过实例验证,该算法可以快速有效地获得满足多约束的最佳工艺参数。

Abstract Rolling element bearings faults may lead to fatal breakdown of machines. Therefore, it is significant be study diagnosis, and the vibration-based methods have received intensive because vibration signals collected from carry rich information on machine health conditions, possible obtain vitalcharacteristic through using signal processing techniques. This paper proposes a novel diagnosis method about bearing faults, first, new pattern recognition proposed diagnose interval value...

Abstract Single‐atom nanotherapies have received numerous attention in malignant oncotherapy. However, the insufficient enzyme substrate and upregulation of heat shock proteins during therapeutic interventions are seldom concurrently noticed. Herein, a novel gas empowered dual‐cascade synergistic treatment strategy is demonstrated with domino effect, which can sequentially reinforce single‐atom nanozyme (SAzyme)‐based enzymatic therapeutics mild photothermal therapy (PTT) (< 45 °C). In...

Abstract The grate cooler is a key piece of equipment for cooling cement clinker, whose parameter adjustment has notable influence on energy consumption and operation. This article proposes multi-objective set-point optimization control method the system, which takes into account efficiency evaluation. Based analysis cooler, secondary air temperature, tertiary outlet clinker temperature are used as evaluation indicators, model established to construct function. After that, pressure set point...

The Extended Kalman Filtering (EKF) algorithm is the mainstream for State of charge (SOC) estimation. uncertainty noise covariance matrix can slow down EKF algorithm's correction state variables, and even make filtering process unstable or divergent, thereby reducing accuracy SOC Here, an improved Filter with Grey Wolf Optimization developed to address above issue. Firstly, a first-order Thevenin lithium battery model established identify parameters. Secondly, it used optimize random EKF....

The revised electric power of TQNPC unit 2 was insufficient at the assessment test. Hitachi supplier considered that output caused by too large flow area high pressure cylinder. After nozzle modification had not been improved significantly. In this paper, characteristic (CFA) used to evaluate turbine capacity. results showed CFA values cylinder and low were both large, but also within design margin (3-5%). reason mismatch with According nuclear plant diagnosis analysis models, thermal...

RFID is one of the most important technologies in Internet Things (IoT), which has been widely used all kinds fields.However, a key problem tag collision when multiple tags reflect simultaneously to reader.In traditional algorithm, slot location always ignored.We present an anti-collision algorithm based on estimation and this paper.The technique can be divided into two parts: precisely location.Simulation test results show that proposed performs better than despite its simplicity.

Objective To investigate casualty management onboard naval vessels and identify demands on medical systems, as well the scheme of system allocation. Methods A questionnaire survey personal interviews were performed among ship surgeons personnel vessels. Then, results analyzed statistically by using Excel software. Results The features pattern diseases injuries crew during daily normal activity prolonged deployment at sea screened, systems ships existing problems...

Abstract Aiming at the damage of prefabricated counter bore elbow scribble pressure pipeline, a test system is established based on ultrasonic guided wave technology, and end echo interference eliminated by arranging multi-channel sensor array to achieve accurate positioning pipeline return measured Comparing amplitude value with 3% DAC curve calculate pipe cross-sectional loss rate, results show that average relative error between monitored rate actual 3.46%, location 2.05%.