Andrew D. Lellis

ORCID: 0000-0001-6759-0517
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About
Contact & Profiles
Research Areas
  • CRISPR and Genetic Engineering
  • Plant Virus Research Studies
  • RNA and protein synthesis mechanisms
  • Plant and Fungal Interactions Research
  • Photosynthetic Processes and Mechanisms
  • Plant Molecular Biology Research
  • Transgenic Plants and Applications
  • Plant-Microbe Interactions and Immunity

The University of Texas at Austin
2010-2019

Oregon State University
2002-2004

Washington State University
2002

Texas A&M University
1997

Multicellular eukaryotes produce small RNA molecules (approximately 21-24 nucleotides) of two general types, microRNA (miRNA) and short interfering (siRNA). They collectively function as sequence-specific guides to silence or regulate genes, transposons, viruses modify chromatin genome structure. Formation activity RNAs requires factors belonging gene families that encode DICER (or DICER-LIKE [DCL]) ARGONAUTE proteins and, in the case some siRNAs, RNA-dependent polymerase (RDR) proteins....

10.1371/journal.pbio.0020104 article EN cc-by PLoS Biology 2004-02-24

The V20 cultivar of Nicotiana tabacum was shown previously to exhibit a strain-specific restriction long-distance movement tobacco etch potyvirus (TEV). In V20, both TEV-HAT and TEV-Oxnard strains are capable genome amplification cell-to-cell movement, but only is systemic infection by vasculature-dependent movement. To investigate the basis for host-specific TEV, chimeric virus genomes were assembled from TEV-Oxnard. Viruses containing coding regions HC-Pro and/or capsid protein (CP), two...

10.1128/jvi.71.11.8624-8631.1997 article EN Journal of Virology 1997-11-01

Arabidopsis thaliana knockout lines for the plant-specific eukaryotic translation initiation factors eIFiso4G1 (i4g1) and eIFiso4G2 (i4g2) genes have been obtained. To address potential functional redundancy of these genes, homozygous double mutant were generated by crossing individual lines. Both single plants analyzed changes in gross morphology, development, responses to selected environmental stressors. Single gene knockouts appear minimal effect on germination rate, growth flowering...

10.1007/s11103-010-9670-z article EN cc-by-nc Plant Molecular Biology 2010-08-07
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