A5086537561- Analytical chemistry methods development
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Microfluidic and Capillary Electrophoresis Applications
- Nanofabrication and Lithography Techniques
- Electrochemical sensors and biosensors
- Photonic Crystals and Applications
- Analytical Chemistry and Chromatography
- Photonic and Optical Devices
- Polymer Surface Interaction Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Surface Modification and Superhydrophobicity
- Lubricants and Their Additives
- Analytical Chemistry and Sensors
- Microfluidic and Bio-sensing Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Tribology and Wear Analysis
- Nanocluster Synthesis and Applications
- Advanced Sensor and Energy Harvesting Materials
- Mycotoxins in Agriculture and Food
- ZnO doping and properties
- Quantum Dots Synthesis And Properties
- Organic Electronics and Photovoltaics
- Graphene and Nanomaterials Applications
- Oral and gingival health research
Affiliated Hospital of Jining Medical University
2024
Shanghai Tenth People's Hospital
2024
Tongji University
2024
Anhui University
2024
Shanghai University
2018-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2023
China Pharmaceutical University
2023
Union Hospital
2023
Huazhong University of Science and Technology
2014-2023
Hangzhou Medical College
2022
Organic photovoltaic circuits are monolithically fabricated directly on a variety of common paper substrates using oxidative chemical vapor deposition to print conformal conductive polymer electrodes. The arrays produce >50 V, power electronic displays in ambient indoor lighting, and can be tortuously flexed folded without loss function. Detailed facts importance specialist readers published as ”Supporting Information”. Such documents peer-reviewed, but not copy-edited or typeset. They made...
Poly[2-(dimethylamino)ethyl methacrylate-co-ethylene glycol dimethacrylate] (PDE) thin films were synthesized via initiated chemical vapor deposition (iCVD) and reacted with 1,3-propane sultone to obtain the zwitterionic structure. The cross-linker ethylene dimethacrylate (EGDMA) was utilized make copolymer insoluble in water. composition of tuned by varying flow rates precursors calculated from Fourier transform infrared spectroscopy (FTIR) spectra. coatings covalently grafted on reverse...
Successfully commercialized poly(ethylene oxide) (PEO)-based solid polymer batteries (SPBs) are expected to continuously play a key role in the next generation of high-energy density lithium-ion battery technologies. However, introduction high-voltage cathodes, accompanied by safety concerns such as PEO decomposition and associated gas release, is worthy more attention. This study employs situ DEMS gassing behavior LiCoO2|PEO-LiTFSI|Li SPBs. The experiments, together with theory...
Chemical Vapor Deposition (CVD) methods significantly augment the capabilities of traditional surface modification techniques for designing polymeric surfaces. In CVD polymerization, monomer(s) are delivered to through vapor phase and then undergo simultaneous polymerization thin film formation. By eliminating need dissolve macromolecules, enables insoluble polymers be coated prevents solvent damage substrate. Since de-wetting tension effects absent, coatings conform geometry underlying...
We describe a potentially universal, simple and cheap method to prepare water-compatible molecularly imprinted polymer nanoparticles (MIP-NPs) as synthetic antibodies against proteins. The strategy is based on solid phase synthesis approach where glass beads (GBs) are functionalized with metal chelate, acting general affinity ligand attract surface-bound histidines present This configuration enables an oriented immobilization of the proteins, upon which thermoresponsive MIP-NPs synthesized....
Hyaluronic acid (HA) is a glycosaminoglycan that plays many roles in health and disease key biomarker of certain cancers. Therefore, its detection at an early stage, by histochemical methods, importance. However, intracellular HA can be masked other HA-binding macromolecules, rendering visualization somehow problematic. We show fluorescent molecularly imprinted polymer nanogels (MIP-NPs), localize detect HA. MIP-NPs were synthesized solid-phase synthesis on glass beads (GBs). GBs...
We describe the preparation and characterization of synthetic antibodies based on molecularly imprinted polymer nanoparticles (MIP-NPs) for recognition binding highly conserved specific peptide motif SWSNKS (3S), an epitope envelope glycoprotein 41 (gp41) human immunodeficiency virus type 1 (HIV-1). This is implicated in decline CD4+ T cells leads to deterioration immune system during HIV infection. Therefore, development MIP-NPs that can target block 3S prevent subsequent cascade...
Poly(4-aminostyrene) (PAS) thin films were synthesized via initiated chemical vapor deposition (iCVD) with tert-butyl peroxide as the initiator, representing first time that a library of iCVD functional groups has been extended to amine moieties. The retention pendent functionality was confirmed by Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron (XPS). Scanning electron microscope (SEM) reveals PAS coatings are conformal over nonplanar structures. Fluorescence...
We describe the application of a fluorescently labeled water-soluble core–shell molecularly imprinted polymer (MIP) for fluorescence immunoassay (FIA) to detect trypsin. p-Aminobenzamidine (PAB), competitive inhibitor trypsin, was immobilized in wells microtiter plate enabling capture trypsin an oriented position, thus maintaining its native conformation. Fluorescent MIP nanoparticles, which bound selectively were used quantification. The prepared by multistep solid-phase synthesis approach...
We describe a pH responsive drug delivery system which was fabricated using novel approach to functionalize biodegradeable porous silicon (pSi) by initiated chemical vapor deposition (iCVD). The assembly involved first loading model (camptothecin, CPT) into the pores of pSi matrix followed capping with thin copolymer film poly(methacrylic acid-co-ethylene dimethacrylate) (p(MAA-co-EDMA)) via iCVD. Release CPT from uncoated identical in two buffers at 1.8 and 7.4. In contrast, linear release...
This paper reports on the fabrication of a pSi-based drug delivery system, functionalized with an initiated chemical vapor deposition (iCVD) polymer film, for sustainable and temperature-dependent drugs. The devices were prepared by loading biodegradable porous silicon (pSi) fluorescent anticancer camptothecin (CPT) coating surface temperature-responsive poly(N-isopropylacrylamide-co-diethylene glycol divinyl ether) (pNIPAM-co-DEGDVE) or non-stimulus-responsive poly(aminostyrene) (pAS) via...
Molecular imprinting represents one of the most promising strategies to design artificial enzyme inhibitors. However, study molecularly imprinted inhibitors (MIEIs) remains at a primary stage. Advanced applications MIEIs for cell regulation have rarely been explored. Using solid-phase oriented strategy so as leave active site enzymes accessible, we synthesized two that exhibit high specificity and potent inhibitory effects (inhibition constant low nM range) towards trypsin angiogenin. The...
Breast cancer is one of the most common malignant diseases among women worldwide, and existence breast stem cells closely associated with poor outcomes. Herein, we report an electrochemical phenotyping method to characterize stemlike phenotype in cancer, offering a low-cost but robust choice other than highly expensive experience-dependent flow cytometry. Specially, after immune-magnetic beads-assisted enrichment, situ programmable DNA circuit designed using capture probes bring toeholds for...
Abstract Biosensors are a class of smart devices fabricated for target analyte detection. A biosensor is commonly made three basic components: specific bioreceptor, physicochemical transducer, and signal processing device. The bioreceptor part features one the more crucial technologies to perform detection analytes. They make use various molecular recognition elements, such as enzymes, natural receptors, antibodies, nucleic acid aptamers, even synthetic receptors. Then, events these...
Molecularly imprinted polymers (MIPs) for salicylic acid were synthesized and evaluated in aqueous environments the aim to apply them as drug delivery carriers. One organic MIP one inorganic based on sol–gel process synthesized. The was prepared by radical polymerization using stoichiometric functional monomer, 1‐(4‐vinylphenyl)‐3‐(3,5‐bis(trifluoromethyl)phenyl)urea, which can establish strong electrostatic interactions with –COOH of acid. 3‐(aminopropyl)triethoxysilane...