A5077181248- Wnt/β-catenin signaling in development and cancer
- Ovarian cancer diagnosis and treatment
- Eicosanoids and Hypertension Pharmacology
- Medicinal Plant Pharmacodynamics Research
- Phytoestrogen effects and research
- Renin-Angiotensin System Studies
- Pulmonary Hypertension Research and Treatments
- Natural product bioactivities and synthesis
- Ginseng Biological Effects and Applications
- Kruppel-like factors research
- Cancer Cells and Metastasis
- Caveolin-1 and cellular processes
- Traditional Chinese Medicine Analysis
- Biomarkers in Disease Mechanisms
- Cytokine Signaling Pathways and Interactions
- Cancer, Lipids, and Metabolism
Union Hospital
2015-2018
Huazhong University of Science and Technology
2015-2018
Signal transducers and activators of transcription (STAT) family are critical factors, which have been proved as prognostic predictors for a number cancers. However, the roles STAT in breast cancer patients remain dispute. In present study, we mined 'Kaplan-Meier plotter' (KM plotter) online database to explore mRNA expression including overall survival (OS), progression-free (PFS), well post-progression (PPS). The results suggest high all individual STATs, except STAT1 STAT2, significantly...
Decreased epithelial cadherin (E-cadherin) expression is hypothesized to be related poor prognosis of ovarian cancer, but the predictive value still inconsistent. We conducted an updated meta-analysis with a total 16 studies enrolling 1720 patients estimate prognostic decreased E-cadherin in cancer. Reduced was significantly associated overall survival (HR = 1.74, 95% CI: 1.40-2.17) and progression-free 1.45, 1.12-1.86) large heterogeneity for survival. In addition, we found that correlated...