- Adolescent and Pediatric Healthcare
- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastrointestinal motility and disorders
- Childhood Cancer Survivors' Quality of Life
- Health, psychology, and well-being
- Digital Mental Health Interventions
- Pediatric Pain Management Techniques
- Child and Adolescent Psychosocial and Emotional Development
- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Tryptophan and brain disorders
- Mobile Health and mHealth Applications
- Health Systems, Economic Evaluations, Quality of Life
- Mental Health Research Topics
- Diet and metabolism studies
- Anesthesia and Pain Management
- Sleep and related disorders
- Bipolar Disorder and Treatment
- Eating Disorders and Behaviors
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Mental Health Treatment and Access
- Stress Responses and Cortisol
University of Pittsburgh
2016-2025
Akron Children's Hospital
2024-2025
University of Pittsburgh Medical Center
2015-2024
UPMC Center for High Value Health Care
2021-2022
Bridge University
2022
Children's Hospital of Pittsburgh
2006-2016
Boston Children's Hospital
2002-2014
GTx (United States)
2014
Case Western Reserve University
1997-2013
Pittsburg State University
2013
Abstract Background The Crohn’s & Colitis Foundation’s Cost of Inflammatory Bowel Disease (IBD) Care Initiative seeks to quantify the wide-ranging health care costs affecting patients living with IBD. We aimed (1) describe annualized direct and indirect for disease (CD) or ulcerative colitis (UC), (2) determine longitudinal drivers these costs, (3) characterize cost newly diagnosed patients. Methods analyzed Optum Research Database from years 2007 2016, representing commercially insured...
Ulcerative colitis (UC) and Crohn disease (CD), collectively referred to as inflammatory bowel (IBD), are chronic disorders that can affect the gastrointestinal tract of children adults. Like other autoimmune processes, cause(s) these remain unknown but likely involves some interplay between genetic vulnerability environmental factors. Children, in particular with UC or CD, present their primary care providers similar symptoms, including abdominal pain, diarrhea, weight loss, bloody stool....
Pain in patients with chronic pancreatitis (CP) remains the primary clinical complaint and source of poor quality life. However, clear guidance on evaluation treatment is lacking.
This study assessed the rates of depressive symptoms in older children and adolescents with inflammatory bowel disease (IBD) associations between IBD characteristics.One hundred two youths (aged 11-17 years) seen consecutively a gastroenterology clinic were screened for using Children's Depression Inventory (CDI). Subjects CDI scores > or = 12 evaluated current psychiatric diagnoses Schedule Affective Disorders Schizophrenia School-Age Children-Present Lifetime Version (K-SADS-PL). Disease...
It is estimated that of the >1 million individuals in United States with inflammatory bowel disease (IBD), ≈100,000 are children. IBD begins childhood affects individual at a critical period growth and development. Children Crohn's ulcerative colitis may experience complications such as failure, school absence, depression. In addition, because children have fewer environmental confounders smoking, be an excellent population to study microbial immune interactions. Despite these opportunities,...
Abstract Several lines of anatomical, biochemical, and pharmacological evidence have suggested that specific high affinity neurotensin binding sites are associated with dopamine‐containing neurons in the rat ventral tegmentum. In present study we confirmed quantified extent this association by combining monoiodinated radioautography tyrosine hydroxylase immunohistochemistry on adjacent 5–10μm‐thick midbrain sections. We found 95–100% hydroxylase‐immunoreactive detected all subdivisions...
Abdominal pain is a common symptom in patients with inflammatory bowel disease (IBD) and has profound negative impact on patients’ lives. There are growing data suggesting that variably related to the degree of active inflammation. Given multifactorial etiologies underlying pain, treatment abdominal IBD population best accomplished by individualized plans. This review covers four clinically relevant categories IBD, namely, inflammation, surgical complications, bacterial overgrowth,...
Objective To evaluate the feasibility and effectiveness of an enhanced cognitive–behavioral therapy (CBT), Primary Secondary Control Enhancement Training (PASCET-PI-2), for physical (obesity) emotional (depression) disturbances in adolescents with polycystic ovary syndrome (PCOS). Method In open trial, 12 PCOS, obesity, depression underwent eight weekly sessions three family-based CBT by lifestyle goals (nutrition exercise), illness narrative (meaning having PCOS), family psychoeducation...
New models of health care have emerged over the past decade. Accountable organizations and patient-centered medical homes are designed to improve patient experience, enhance quality, decrease cost. These been developed in primary domain yet be tested specialty care. Certain chronic diseases require principal by a specialist or team. The home would provide for specific populations patients whose derives from single disease. This article defines parameters provides payer-provider experience...