A5101438305- CAR-T cell therapy research
- Biosimilars and Bioanalytical Methods
- Cancer Immunotherapy and Biomarkers
- Single-cell and spatial transcriptomics
- Viral Infectious Diseases and Gene Expression in Insects
- Immune Cell Function and Interaction
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Growth Hormone and Insulin-like Growth Factors
- Family and Patient Care in Intensive Care Units
- Dental Anxiety and Anesthesia Techniques
- Airway Management and Intubation Techniques
- Diet and metabolism studies
- Nosocomial Infections in ICU
- SARS-CoV-2 and COVID-19 Research
- Immunodeficiency and Autoimmune Disorders
- Metal complexes synthesis and properties
- Chemistry and Stereochemistry Studies
- Immunotherapy and Immune Responses
- Pituitary Gland Disorders and Treatments
- Leech Biology and Applications
- Pancreatic function and diabetes
- Bacterial Infections and Vaccines
- Anesthesia and Neurotoxicity Research
- Parasite Biology and Host Interactions
Sriram Chandra Bhanja Medical College Hospital
2022
University of Calcutta
2022
Children's Hospital of Philadelphia
2021
University of Pennsylvania
2013-2019
KPC Medical College and Hospital
2019
Medical College and Hospital, Kolkata
2019
Regional Cancer Center, Thiruvananthapuram
2017
Indian Association for the Cultivation of Science
1971
Abstract Translational data on chimeric antigen receptor (CAR) T-cell trials indicate that the presence of naïve T cells in premanufacture product is important to clinical response and persistence. In anticipation developing CAR for other tumors, we investigated distribution from children with solid tumors lymphomas at diagnosis after every cycle chemotherapy. We found patients enriched stem central memory expanded well vitro, but majority tumor types showed chemotherapy-related depletion...
The adoptive transfer of chimeric antigen receptor (CAR) T cells represents a breakthrough in clinical oncology, yet both between- and within-patient differences autologously derived are major contributor to therapy failure. To interrogate the molecular determinants CAR T-cell persistence, we extensively characterized premanufacture 71 patients with B-cell malignancies on trial receive anti-CD19 therapy. We performed RNA-sequencing analysis sorted subsets from all patients, followed by...
Background: Ventilator associated pneumonia in critically ill patients are with high morbidity and mortality. Patients who mechanically ventilated at risk of acquiring respiratory infections due to complex interplay between the endotracheal tube, host immunity virulence invading bacteria. To start empiric antimicrobial therapy knowledge local resistance patterns essential. Objectives our study was sensitivity among organisms isolated from aspirates VAP.Methods: This is a prospective...
Sedation in paediatric cancer for fractionated radiation treatment (RT) is unique as the child has to be still accurate delivery of RT, monitoring from a remote location and sedation repeated multiple sessions RT. The present study was undertaken compare efficacy intranasal dexmedetomidine with oral midazolam ketamine combination during RT oncology.Ninety children aged between 3-6 years, planned 21 fractions were randomised receive 2 μg/kg (group D) or 0.2 mg/kg 5 MK). radiotherapy divided...
<div>Abstract<p>Translational data on chimeric antigen receptor (CAR) T-cell trials indicate that the presence of naïve T cells in premanufacture product is important to clinical response and persistence. In anticipation developing CAR for other tumors, we investigated distribution from children with solid tumors lymphomas at diagnosis after every cycle chemotherapy. We found patients enriched stem central memory expanded well <i>in vitro</i>, but majority tumor types...
<div>Abstract<p>The adoptive transfer of chimeric antigen receptor (CAR) T cells represents a breakthrough in clinical oncology, yet both between- and within-patient differences autologously derived are major contributor to therapy failure. To interrogate the molecular determinants CAR T-cell persistence, we extensively characterized premanufacture 71 patients with B-cell malignancies on trial receive anti-CD19 therapy. We performed RNA-sequencing analysis sorted subsets from all...
<div>Abstract<p>The adoptive transfer of chimeric antigen receptor (CAR) T cells represents a breakthrough in clinical oncology, yet both between- and within-patient differences autologously derived are major contributor to therapy failure. To interrogate the molecular determinants CAR T-cell persistence, we extensively characterized premanufacture 71 patients with B-cell malignancies on trial receive anti-CD19 therapy. We performed RNA-sequencing analysis sorted subsets from all...
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<p>Supplementary Methods</p>
<p>Supplementary Methods</p>
Abstract The aqueous polymerisation of methyl methacrylate initiated by the chromate/arsenite system has been studied. It is observed that above redox catalysed OH ⊖ though parent reaction between chromate and arsenite H ⊕ . also traces Cu 2⊕ inhibit both polymerization as reaction. From these observations it concluded (1) intermediate valency states chromium no initiating power in alkali solution (2) a chain involving single electron transfer As 4⊕ thus produced species.