A5018775170- Helminth infection and control
- Parasitic Diseases Research and Treatment
- Insect Utilization and Effects
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Insect and Pesticide Research
- Phytochemistry and biological activities of Ficus species
- Nematode management and characterization studies
University of Ngaoundéré
2017-2024
Acacia nilotica fruits with high tannin content are used in the northern parts of Cameroon as anti-filarial remedies by traditional healers. In this study, hydro-alcoholic fruit extract (crude (CE)) and, one main constituents its most active fractions, (+)-catechin-3-O-gallate (CG), well four related proanthocyanidins, (-)-epicatechin-3-O-gallate (ECG), (+)-gallocatechin (GC), (-)-epigallocatechin (EGC) and (-)-epigallocatechin-3-O-gallate (EGCG), were assessed for their potential vitro...
The front line molecules from filarial worms and other nematodes or helminthes are their Excretory-Secretory (ES) products. Their interaction with the host cells, proteins immune system accounts for skin eye pathology hyposensitivity observed in human onchocerciasis. ES products adult worms' crude extracts Onchocerca ochengi, a nematode that infects African zebu cattle, were utilized present study as model studying volvulus causes river blindness man.
Onchocerciasis is one of the tropical neglected diseases (NTDs) caused by nematode Onchocerca volvulus. Control strategies currently in use rely on mass administration ivermectin, which has marked activity against microfilariae. Furthermore, development resistance to ivermectin was observed. Since vaccine and safe macrofilaricidal treatment onchocerciasis are still lacking, there an urgent need discover novel drugs. This study undertaken investigate anthelmintic Lophira lanceolata cattle...
Onchocerciasis is a filarial disease caused by Onchocerca volvulus and transmitted through the bite of blackfly genus Simulium. The microfilaricidal drug ivermectin has long been relied on to treat onchocerciasis. Nowadays, focus complete elimination development macro-filaricidal drugs. In this study, hydro-alcoholic extract from Annona senegalensis leaves was screened for micro- macrofilaricidal activities against cattle parasitic nematode ochengi free-living Caenorhabditis elegans, both...
Abstract Background Human onchocerciasis caused by the filarial worm, Onchocerca volvulus is a parasitic that forms nodules under skin. In developing countries, it has been estimated more than 80% of population rely on traditional medicines for their primary healthcare needs. The aim this work was to assess nematicidal activities Aloe vera ochengi and Caenorahbditis elegans determine phytochemical compounds. Methods Nodules were collected from umbilical region infected cattle, dissected male...