A5080452250- Insect Resistance and Genetics
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Drug Transport and Resistance Mechanisms
- Insect Pest Control Strategies
- Scientific Computing and Data Management
- Insect and Pesticide Research
- Research Data Management Practices
- Insect-Plant Interactions and Control
- Big Data and Business Intelligence
- Rangeland and Wildlife Management
- Piperaceae Chemical and Biological Studies
- Turfgrass Adaptation and Management
- Surfactants and Colloidal Systems
- Analytical Methods in Pharmaceuticals
- Lepidoptera: Biology and Taxonomy
- Genetics, Bioinformatics, and Biomedical Research
- Lichen and fungal ecology
- Viral Infectious Diseases and Gene Expression in Insects
- Plant and fungal interactions
- Barrier Structure and Function Studies
- Plant Toxicity and Pharmacological Properties
- Antibiotics Pharmacokinetics and Efficacy
- Biocrusts and Microbial Ecology
- Aquatic Ecosystems and Phytoplankton Dynamics
North-West University
2016-2022
Michigan State University
1996
Therapeutic macromolecules (e.g., protein and peptide drugs) present bioavailability challenges via extravascular administration. The nasal route presents an alternative non-invasive for these drugs, although low remains challenging. Co-administration of permeation enhancers is a promising formulation approach to improve the delivery poorly bioavailable drugs. aim this study was prepare characterize chitosan microparticulate formulations containing macromolecular model compound (fluorescein...
The African maize stem borer, Busseola fusca, feeds on a limited number of host plant species (Calatayud et al. 2014), which include crops such as maize, pearl millet and sorghum. This pest occurs throughout sub-Saharan Africa where it causes economic damage to sorghum (Kfir 2002). In an attempt combat lepidopteran borers, genetically modified Bt that express insecticidal Cry toxins were developed kill larvae feed these plants (George 2011). was introduced into South during 1998 within the...
Contemporary research, particularly when addressing the most significant transdisciplinary research challenges, cannot effectively be done without a range of skills relating to data management, analysis, and cyberinfrastructure (CI). These CI are common all disciplines that conduct data-centric research. Research Data Science acts as vital component scientific process. In grassroots attempt address this gap, CODATA-RDA Schools (SoRDS) was founded in 2016 provide instruction on foundational...
The effect of functional excipients (i.e. chitosan, sodium lauryl sulphate, NaHCO3, and CaCO3) formulated in multiple-unit pellet system (MUPS) tablets has been investigated on the dissolution permeability furosemide, a BCS class IV compound. Spherical beads were produced compressed into MUPS tablets. tablet formulations evaluated for hardness, disintegration, mass variation, friability, (pH 1.2, pH 4.6, 7.4). Ex vivo studies conducted across excised pig tissues (pyloric antrum duodenal...
Background:: Knowledge of the permeation characteristics new chemical entities across biological membranes is essential to drug research and development. Transport medium composition may affect absorption compounds during in vitro transport testing. To preserve predictive values screening tests, possible influence media on solubility model drugs activities tight junctions efflux transporter proteins (e.g., Pglycoprotein) must be known. Objective:: The aim this study was compare impact...
Introduction: There is growing concern that co-administered herbal medicines may alter the pharmacokinetics and, therefore, efficacy and toxicity of Western drugs. The aim this study was to investigate potential membrane permeation modulating effects four extracts, i.e., Harpagophytum procumbens, Hoodia gordonii, Leonotis leonurus, Vitis vinifera on a model compound, Rhodamine 123 (RH-123). Methods: An in vitro model, excised pig intestinal tissue, mounted test chambers Sweetana-Grass...