A5016379193- Blood transfusion and management
- Genital Health and Disease
- Blood donation and transfusion practices
- Urologic and reproductive health conditions
- Blood groups and transfusion
- Healthcare Policy and Management
- Female Genital Mutilation/Cutting Issues
- Chronic Kidney Disease and Diabetes
- Hemoglobinopathies and Related Disorders
- Patient Satisfaction in Healthcare
- Healthcare cost, quality, practices
- Erythrocyte Function and Pathophysiology
- Urological Disorders and Treatments
- Hepatitis B Virus Studies
- Trauma and Emergency Care Studies
- Organ Donation and Transplantation
- Glaucoma and retinal disorders
- COVID-19 and Mental Health
- Data-Driven Disease Surveillance
- Blood disorders and treatments
- Ophthalmology and Visual Impairment Studies
- Experimental Behavioral Economics Studies
- Injury Epidemiology and Prevention
- Emergency and Acute Care Studies
- Central Venous Catheters and Hemodialysis
Johns Hopkins University
2013-2022
Johns Hopkins Medicine
2013-2021
National Bureau of Economic Research
2021
Sawai ManSingh Medical College and Hospital
2017
University of Minnesota
2013
Brigham and Women's Hospital
2013
Sickle cell disease is associated with extensive health care utilization; estimated lifetime costs exceed $460,000 per patient. Approximately 30% of chronically transfused sickle patients become alloimmunized to red blood antigens, but these cannot be identified a priori. Prospective antigen matching can prevent alloimmunization, costly and may not benefit most patients.A Markov-based model was constructed compare the financial implications four alternative antigen-matching strategies for...
To evaluate the expected change in prevalence of male circumcision (MC)-reduced infections and resulting health care costs associated with continued decreases MC rates. During past 20 years, rates have declined from 79% to 55%, alongside reduced insurance coverage.
BACKGROUND Hemolytic disease of the fetus and newborn, classically caused by maternal–fetal incompatibility Rh blood group D antigen, can be prevented RhIG prophylaxis. While prophylactic practices for pregnant women with serologic weak phenotypes vary widely, RHD genotyping could provide clear guidance management. This analysis evaluated financial implications using to guide prophylaxis among females. STUDY DESIGN AND METHODS A Markov‐based model was constructed evaluate costs females...
Background Prophylactic antigen‐matching can reduce alloimmunization rates among chronically transfused patients with sickle cell disease (SCD), but this matching increases costs and may only benefit 30% of patients. We assessed the clinical financial value a potential assay for risk that would allow targeted antigen‐matching. Study Design Methods A Markov‐based model evaluated direct medical events over 10 to 20 years (simple or exchange) SCD. Four strategies were evaluated: prospective...
Background Allergic transfusion reactions ( ATRs ) are among the most common complications of transfusion. Storage in platelet additive solution PAS has been shown to reduce from apheresis platelets APs ). This study evaluated cost‐effectiveness using storage as an alternative method . Study Design and Methods A Markov‐based decision tree was constructed compare ATR rates associated costs expected current practice strategies stored The potential use pretransfusion medication also...
Bacterial contamination of platelets remains the leading infectious risk from blood transfusion. Pathogen reduction (PR), point-of-release testing (PORt), and secondary bacterial culture (SBC) have been proposed as alternative control strategies, but a comprehensive financial comparison has not conducted.A Markov-based decision tree was constructed to model clinical impact PR, PORt, SBC, well baseline strategy involving routine only. Hospitals were assumed acquire leukoreduced apheresis on...
BACKGROUND Effective and financially viable mitigation approaches are needed to reduce bacterial contamination of platelets in the US. Expected costs large‐volume delayed sampling (LVDS), which would be performed by a blood center prior shipment hospital, were compared those pathogen reduction (PR), point‐of‐release testing (PORt), secondary culture (SBC). METHODS Using Markov‐based decision‐tree model, financial clinical impact implementing all variants LVDS, PR, PORt, SBC described FDA...
The financial implications of male circumcision (MC) scale-up in sub-Saharan Africa associated with reduced HIV have been evaluated. However, no analysis has incorporated the expected reduction a comprehensive set other sexually transmitted infections including human papillomavirus, herpes simplex virus type 2, genital ulcer disease, bacterial vaginosis, and trichomoniasis.
Abstract Background In 2019, the United States Food and Drug Administration published its final recommendations to mitigate bacterial contamination of platelets. We sought evaluate our secondary culture (SBC) strategy in light those recommendations. Study Design Methods A retrospective analysis was conducted SBC data (October 2016‐2019) at institution. performed upon receipt (Day 3 after collection); 5 mL platelet product inoculated aseptically into an aerobic bottle incubated 35°C for days....
Male circumcision (MC) is an effective intervention to reduce HIV acquisition in men Africa. We conducted a cost analysis using longitudinal data on expenditures services and community mobilization estimate the marginal of MC over time understand drivers during scale-up.We used series with monthly records from 2008 2013, for total 72 observations, Rakai Program Uganda. Generalized linear models were procedure.The per mobile camp was $23 (P < 0.01) static facilities $35 0.1). Major included...
Abstract We study whether vouchers without and with value information encourage attendance of already free follow‐up appointments among low‐income minority individuals referred for evaluation possible eye disease. Between May 2017 September 2018, 821 from 114 screening events across Baltimore City were offered (1) standard referral a appointment prescription glasses, (2) paper voucher described as redeemable or (3) an otherwise identical which also indicated the monetary ($250). Under all...
Background: Meditation is a mind and body practice for increasing calmness physical relaxation, improving psychological balance, coping with illness, enhancing overall health well-being. Many studies have already been carried out to see the effect of Yoga, Pranayam, meditation, Sudarhan Kriya on physiological parameters, but till date, there not single study which shows cumulative yoga, pranayam, meditation along sudarshankriya parameters. Methods: This observational was conducted in...