- Essential Oils and Antimicrobial Activity
- Supramolecular Self-Assembly in Materials
- Bee Products Chemical Analysis
- Peptidase Inhibition and Analysis
- Plant Toxicity and Pharmacological Properties
- Insect and Pesticide Research
- Botanical Research and Chemistry
- Psidium guajava Extracts and Applications
- Hydrogels: synthesis, properties, applications
- Mycotoxins in Agriculture and Food
- Nanoparticle-Based Drug Delivery
- Neuropeptides and Animal Physiology
- Nanoplatforms for cancer theranostics
- Phytochemicals and Antioxidant Activities
- Phytochemistry and biological activities of Ficus species
- Chemical Synthesis and Analysis
- Phytochemistry and Biological Activities
Universidade do Porto
2018-2023
Rede de Química e Tecnologia
2018-2023
Pharmac
2019
Supramolecular plasmonic magnetogels comprising two different nanoparticle architectures were developed and evaluated as potential nanocarriers for multimodal cancer therapy with reversible photothermia capabilities tuneable drug release.
The use of peptide–drug conjugates is emerging as a powerful strategy for targeted drug delivery. Previously, we have found that peptides conjugated to non-steroidal anti-inflammatory (NSAID), more specifically naproxen–dehydrodipeptide conjugates, readily form nanostructured fibrilar supramolecular hydrogels. These hydrogels were revealed efficacious nano-carriers delivery applications. Moreover, the incorporation superparamagnetic iron oxide nanoparticles (SPIONs) rendered responsive...
Pest resistance against fungicides is a widespread and increasing problem, with impact on crop production public health, making the development of new an urgent need. Chemical analyses crude methanol extract (CME) Guiera senegalensis leaves revealed presence sugars, phospholipids, phytosterols, guieranone A, porphyrin-containing compounds, phenolics. To connect chemical composition biological effects, solid-phase extraction was used to discard water-soluble compounds low affinity for C18...
Supramolecular hydrogels where the hydrogelator molecule is endowed with intrinsic pharmacological properties can potentially fulfil a dual function in drug delivery systems as nanocariers for incorporated drugs and active themselves. In this present study, we investigated activities of panel naproxen-dehydrodipeptide conjugates, previously studied their hydrogelation ability nanocarriers drug-delivery applications. A library dehydrodipeptides, containing N-terminal canonical amino acids...