- Optical Imaging and Spectroscopy Techniques
- Functional Brain Connectivity Studies
- Photoacoustic and Ultrasonic Imaging
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Heart Rate Variability and Autonomic Control
- Spectroscopy Techniques in Biomedical and Chemical Research
- Semiconductor Quantum Structures and Devices
- Thermoregulation and physiological responses
- Autism Spectrum Disorder Research
- Mathematical and Theoretical Epidemiology and Ecology Models
- Optical Network Technologies
- Semiconductor Lasers and Optical Devices
- Photonic and Optical Devices
- Optical Coherence Tomography Applications
- Advanced Semiconductor Detectors and Materials
- Neuroscience and Neural Engineering
- Urban Heat Island Mitigation
- Optical Polarization and Ellipsometry
- Smart Grid and Power Systems
- Brain Tumor Detection and Classification
- Ophthalmology and Visual Impairment Studies
- Random lasers and scattering media
- Attention Deficit Hyperactivity Disorder
- Advanced MRI Techniques and Applications
Yan'an University
2025
Sichuan Agricultural University
2025
South China Normal University
2015-2024
Lawrence Livermore National Laboratory
2023-2024
Zhejiang Shuren University
2022
Zhejiang University
2005-2020
Wright State University
2017-2020
Human Factors (Norway)
2020
Xidian University
2017
Peking University
2016
We use near-infrared dynamic multiple scattering of light [diffusing-wave spectroscopy (DWS)] to detect the activation somato-motor cortex in 11 right-handed volunteers performing a finger opposition task separately with their right and left hands. Temporal autocorrelation functions g(1)(r,tau) scattered field are measured during 100-s periods motor alternating resting baseline periods. From an analysis experimental data analytical theory for from three-layer geometry optical dynamical...
The enhanced proliferation of mesenchymal stem cells (MSCs) can be helpful for the clinical translation cell therapy. Low-level laser irradiation (LLLI) has been demonstrated as regulating MSC proliferation. MicroRNAs (miRNAs) are involved in various pathophysiologic processes cells, but role miRNAs LLLI-based promotion remains unclear. We found that level and cycle-associated genes MSCs were increased after LLLI treatment a time-dependent manner. Microarray assays revealed subsets to...
Autism spectrum disorder (ASD) is a developmental syndrome characterized by obvious drawbacks in sociality and communication. It has crucial significance to exactly discern the individuals with ASD typical controls (TC). Previous imaging studies on ASD/TC identification have made remarkable progress exploration of objective as well biomarkers associated ASD. However, glaring deficiency manifested investigation solely homogeneous small datasets. Thus, we attempted unveil some replicable...
Ultrasound-modulated optical tomography based on the measurement of laser-speckle contrast was investigated. An ultrasonic beam focused into a biological-tissue sample to modulate laser light passing through column inside tissue. The speckle pattern formed by transmitted found depend modulation and could be used for imaging. Variation in reflected inhomogeneity With this technique, two-dimensional images samples as much 25 mm thick were successfully obtained with low-power laser. technique...
Background Pneumonia is considered one of the most important causes morbidity and mortality in world. Bacterial viral pneumonia share many similar clinical features, thus making diagnosis a challenging task. Traditional diagnostic method developments mainly rely on radiological imaging require certain degree consulting experience, which can be inefficient inconsistent. Deep learning for classification multiple modalities, especially integrating data, has not been well explored. Methods The...
Activity of the human visual cortex, elicited by steady-state flickering at 8 Hz, is non-invasively probed multi-speckle diffusingwave spectroscopy (DWS).Parallel detection intensity fluctuations statistically equivalent, but independent speckles allows to resolve stimulation-induced changes in field autocorrelation multiply scattered light less than 2%.In a group 9 healthy subjects we find faster decay function during stimulation periods for data measured with long-distance probe (30 mm...
Autism spectrum disorder (ASD) is a neuro-developmental disorder, characterized by impairments in one's capacity for joint attention. In this study, functional near-infrared spectroscopy (fNIRS) was applied to study the differences activation and connectivity prefrontal cortex between children with autism typically developing (TD) children. 21 ASD 20 TD were recruited perform non-joint attention tasks. Compared children, showed reduced atypical pattern during The development of left might...
The accurate diagnosis of autism spectrum disorder (ASD) is great practical significance in clinical practice. spontaneous hemodynamic fluctuations were collected by functional near-infrared spectroscopy (fNIRS) from the bilateral frontal and temporal cortices typically developing (TD) children with ASD. Since traditional machine learning deep methods cannot make full use potential spatial dependence between variable pairs, require a long time series to diagnose Therefore, we adaptive...
The research reported here focuses on ultrasound-modulated optical tomography based parallel speckle detection. Four methods were investigated for signal acquisition and analysis, in which laser statistics was applied. compared with the previously used four-phase method imaging of all-biological-tissue samples, buried objects also biological tissues. image quality obtained these comparable that method; addition, have advantages reducing time improving signal-to-noise ratio.
We investigate the influence of a non-scattering layer on temporal field autocorrelation function multiple scattered light from multilayer turbid medium such as human head. Data Monte Carlo simulations show very good agreement with predictions correlation-diffusion equation boundary conditions taking into account non-diffusive transport within layer. Field functions measured at surface phantom including agree well theory and when source-receiver distance is significantly larger than depth...
Functional near-infrared spectroscopy (fNIRS) was used to investigate resting state connectivity of language areas including bilateral inferior frontal gyrus (IFG) and superior temporal (STG). Thirty-two subjects participated in the experiment, twenty adults twelve children. Spontaneous hemodynamic fluctuations were recorded, then intra- inter-hemispheric correlations these signals computed. The all hemoglobin components observed significantly higher for than Moreover, differences STG more...
Hemodynamic response to motor execution (ME) and imagery (MI) was investigated using functional near-infrared spectroscopy (fNIRS). We used a 31 channel fNIRS system which allows non-invasive monitoring of cerebral oxygenation changes induced by cortical activation. Sixteen healthy subjects (mean-age 24.5 yeas) were recruited the in concentration hemoglobin examined during right left hand finger tapping tasks kinesthetic MI. To suppress systemic physiological interference, we developed...
An optical imaging technique called ultrasound-modulated computed tomography is demonstrated for tomographic of biological tissues. Ultrasound-modulated signals are extracted from scattered light to provide projection data the image reconstruction. A filtered back-projection algorithm implemented reconstruct an reflecting tissue properties angular and linear scans ultrasonic beam across a sample. This reconstruction-based provides way obtain images cross sections containing scanned axis in...
A novel approach for time-domain diffuse correlation spectroscopy (TD-DCS) has been recently proposed, which the unique advantage by simultaneous measurements of optical and dynamical properties in a scattering medium.In this study, analytical models calculating time-resolved electric-field autocorrelation function is presented multilayer turbid sample, as well semi-infinite medium embedded with small dynamic heterogeneity.To verify models, we used Monte Carlo simulations, demonstrated that...
Hemispheric asymmetry in the power spectrum of low-frequency spontaneous hemodynamic fluctuations has been previously observed autism disorder (ASD). This observation may imply a specific narrow-frequency band which individuals with ASD could show more significant alteration resting-state functional connectivity (RSFC). To test this assumption, we evaluated narrowband RSFC at several frequencies for near-infrared spectroscopy signals recorded from bilateral temporal lobes on 25 children and...
Abstract BACKGROUND: To measure the economic burden of Down syndrome (DS) in China is to facilitate strategic planning development for managing and preventing DS. METHODS: The DS was calculated from direct healthcare costs, non‐health‐care indirect costs. incidence approach employed lifetime a new birth 2003. Most parameters came household health services survey, which given caregivers people with This survey conducted Hebei, Shaanxi, Shanghai 2004. RESULTS: Caregivers 222 were interviewed...
Objective.Feature extraction and recognition in brain signal processing is of great significance for understanding the neurological mechanism autism spectrum disorder (ASD). Resting-state (RS) functional near-infrared spectroscopy measurement provides a way to investigate possible alteration ASD-related complexity resting-state (fNIRS) signals explore relationship between connectivity complexity.Approach.Using multiscale entropy (MSE) fNIRS recorded from bilateral temporal lobes (TLs) on 25...
The marketing literature has demonstrated that political animosity influences consumers’ boycott intention. However, this question rarely been examined in the hospitality setting. Thus, by utilizing cognitive appraisal theory and value-belief-norm theory, study proposes a model to investigate effect of on ethnic dining behavior. To end, examines switching intention examining structural relationships among anticipated negative emotions, personal norms, Study results demonstrate individuals’...