A5081200110- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Bone fractures and treatments
- Hip and Femur Fractures
- Hip disorders and treatments
- Knee injuries and reconstruction techniques
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Osteoarthritis Treatment and Mechanisms
- Prostate Cancer Treatment and Research
- Cancer, Lipids, and Metabolism
- Elasticity and Material Modeling
- Engineering Structural Analysis Methods
- Surgical Sutures and Adhesives
- Bone health and osteoporosis research
- Mechanical Engineering and Vibrations Research
- Cardiac Valve Diseases and Treatments
- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Pelvic and Acetabular Injuries
- Powder Metallurgy Techniques and Materials
- Musculoskeletal Disorders and Rehabilitation
- Anatomy and Medical Technology
- Epigenetics and DNA Methylation
- Hair Growth and Disorders
University of Bath
2016-2024
Offshore Renewable Energy Catapult
2019
University of Edinburgh
2012-2018
Royal Berkshire NHS Foundation Trust
2013
While locking plate fixation is becoming increasingly popular for complex and osteoporotic fractures, many indications compression plating remains the standard choice. This study compares mechanical behaviour of more recent (LCP) device, with traditional dynamic plates (DCPs) in bone varying quality using finite element modelling. The properties considered include orthotropy, inhomogeneity, cortical thinning periosteal apposition associated osteoporosis. effect preloads induced by was...
Objectives Secondary fracture healing is strongly influenced by the stiffness of bone-fixator system. Biomechanical tests are extensively used to investigate and strength fixation devices. The values reported in literature for locked plating, however, vary three orders magnitude. aim this study was examine influence that method restraint load application has on produced, strain distribution within bone, stresses implant locking plate constructs. Methods Synthetic composite bones were...
Opening wedge high tibial osteotomy (HTO) is an established surgical procedure for the treatment of early-stage knee arthritis. Other than infection, majority complications are related to mechanical factors - in particular, stimulation healing at site. This study used finite element (FE) analysis investigate effect plate design and bridging span on interfragmentary movement (IFM) influence fracture stress potential failure.A 10° opening HTO was created a composite tibia. Imaging strain gauge...
When using locked plating for bone fracture fixation, screw loosening is reported as one of the most frequent complications and commonly attributed to an incorrect choice configuration. Choosing a patient-optimized configuration not straightforward there are many interdependent variables that affect device performance. The aim study was evaluate influence locking has on risk how this influenced by quality. This uses finite element models incorporate cortical heterogeneity, orthotropy,...
Objectives Modular junctions are ubiquitous in contemporary hip arthroplasty. The head-trunnion junction is implicated the failure of large diameter metal-on-metal (MoM) hips which currently topic one largest legal actions history orthopaedics (estimated costs stated to exceed $4 billion). Several factors known influence strength these press-fit modular connections. However, different head sizes has not previously been investigated. aim study was establish whether choice size influences...
Synthetic biomechanical test specimens are frequently used for preclinical evaluation of implant performance, often in combination with numerical modeling, such as finite-element (FE) analysis. Commercial and freely available FE packages widely three particular gaining popularity: abaqus (Dassault Systèmes, Johnston, RI), ansys (ANSYS, Inc., Canonsburg, PA), febio (University Utah, Salt Lake City, UT). To the best our knowledge, no study has yet made a comparison these commonly solvers....
Abstract Background Despite favourable outcomes relatively few surgeons offer high tibial osteotomy (HTO) as a treatment option for early knee osteoarthritis, mainly due to the difficulty of achieving planned correction and reported soft tissue irritation around plate used stablise osteotomy. To compare mechanical safety new personalised 3D printed device, created overcome these issues, with an existing generic case-control in silico virtual clinical trial was conducted. Methods Twenty-eight...
Abstract Additive manufacturing, aka three dimensional (3D) printing, is increasingly being used for personalized orthopedic implants. Additively manufactured components normally undergo further processing, in particular 3D printed locking osteosynthesis plates require post‐printing screw thread creation. The aim of this study was to compare threads with machined and hand‐tapped a plate application. Pushout tests were performed on 115 additively specimens tapered holes; additive manufacture...
High Tibial Osteotomy is frequently performed to correct varus knees misalignment and thus prevent end-stage osteoarthritis. Traditional systems lack pre-surgical planning custom-fit fixation plates. A new 3D printed system has been developed for a personalized surgical procedure. This starts with careful correction based on standard preoperative long leg radiograph scan of the knee by Cone-Beam CT, both in weight-bearing. From latter, model proximal tibia reconstructed, which surgery...
High tibial osteotomy (HTO) is an effective surgical treatment for isolated medial compartment knee osteoarthritis; however, widespread adoption limited due to difficulty in achieving the planned correction, and patient dissatisfaction soft tissue irritation. The aim of this study was assess accuracy a novel HTO system with 3D printed specific implants guides using cadaveric specimens. Local ethics committee approval obtained. opening wedge procedure performed on eight cadaver leg Whole...
High tibial osteotomy (HTO) is intended to treat medial knee osteoarthritis by realigning the joint such that loading in during functional activity shifts laterally. The aim of this study was use a novel methodology combining motion analysis and 3D modelling assess efficacy surgery changing location cohort 25 patients treated with personalized HTO. Pre-operatively at 6 months post-surgery, weight-bearing CT gait level walking were performed on all patients, as well clinical evaluations using...
Early-stage knee osteoarthritis is often suitable for treatment with high tibial osteotomy (HTO). This an effective joint-preserving treatment, resulting in good postoperative outcomes. To overcome the limitations of traditional HTO, surgical technique and correction accuracy can be enhanced by personalised procedures using three-dimensional digital planning metal additive manufacturing, The purpose this clinical trial study was to evaluate a new HTO procedure, modern imaging techniques, 3D...
Abstract Blade leading edge erosion has developed into a significant issue for the offshore wind industry. Protection solutions, including polymer coatings and tapes, are often applied to increase blade lifetime. Experimental evaluation of protection systems is typically conducted in whirling arm rain test rigs. Currently, there no thoroughly validated method relate results real-world performance. Furthermore, design rigs not sufficiently limited enable comparison between different Industry...
High tibial osteotomy surgery is a widely successful joint-preserving procedure which alters the hip-knee-ankle axis can delay progression of osteoarthritis; however, conventional surgical procedures do not adequately control posterior slope. This study aimed to determine key variables influencing slope during high and provide simple means implementing findings pre-operative planning.