A5006443577- Acute Myeloid Leukemia Research
- Marine animal studies overview
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Mycorrhizal Fungi and Plant Interactions
- Physiological and biochemical adaptations
- Lichen and fungal ecology
- Multiple Myeloma Research and Treatments
- Neurological disorders and treatments
- Vagus Nerve Stimulation Research
- Gene Regulatory Network Analysis
- Epigenetics and DNA Methylation
- Studies on Chitinases and Chitosanases
- Zebrafish Biomedical Research Applications
- Biocrusts and Microbial Ecology
- Neutropenia and Cancer Infections
- IL-33, ST2, and ILC Pathways
- Antimicrobial Peptides and Activities
- Aquaculture disease management and microbiota
- Parkinson's Disease Mechanisms and Treatments
- Aquaculture Nutrition and Growth
- Microbial Community Ecology and Physiology
- Cancer Genomics and Diagnostics
University Medical Center
2024
University Hospital and Clinics
2024
University of Lübeck
2022-2024
Universitätsklinikum Würzburg
2024
University Hospital Schleswig-Holstein
2022-2024
University of Iceland
2015-2019
The developmental basis of craniofacial morphology hinges on interactions numerous signalling systems. Extensive variation in the polymorphic Arctic charr, a member salmonid family, from Lake Thingvallavatn (Iceland), offers opportunities to find and study such pathways their key regulators, thereby shedding light pathways, genetics trophic divergence.To identify genes involved differences between benthic limnetic we used transcriptome data different morphs, spanning early development,...
In newly diagnosed acute myeloid leukemia, immediate initiation of treatment is standard care. However, deferral antileukemic therapy may be indicated to assess comorbidities or pre-therapeutic risk factors. We explored the impact time from diagnosis on outcomes in leukemia undergoing venetoclax-based two distinct cohorts. By querying Study Alliance Leukemia database and global health network TriNetX, we identified 138 717 patients respectively with an average age 76 72 years who received...
Epithelial to mesenchymal transition (EMT) is a developmental event that hijacked in some diseases such as fibrosis and cancer. In cancer, EMT has been linked increased invasion metastasis generally associated with poor prognosis. this study, we have compared phenotypic functional differences between two isogenic cell lines an profile: D492M D492HER2 are both derived from D492, breast epithelial line stem properties. non-tumorigenic while tumorigenic. Thus, the aim of study was analyze...
Acute myeloid leukemia (AML) is characterized by complex molecular alterations and driver mutations. Elderly patients show increased frequencies of IDH mutations with high chemoresistance relapse rates despite recent therapeutic advances. Besides being associated global promoter hypermethylation, IDH1 mutation facilitated changes in 3D DNA-conformation CTCF-anchor methylation upregulated oncogene expression glioma, correlating poor prognosis. Here, we investigated the role p.R132H altering...
<title>Abstract</title> In newly diagnosed acute myeloid leukemia, immediate initiation of treatment is standard care. However, deferral antileukemic therapy may be indicated to assess comorbidities or pre-therapeutic risk factors. We explored the impact time from diagnosis on outcomes in leukemia undergoing venetoclax-based two distinct cohorts. By querying Study Alliance Leukemia database and health network TriNetX, we identified 138 717 patients respectively with an average age 76 72...
<title>Abstract</title> In newly diagnosed acute myeloid leukemia, immediate initiation of treatment is standard care. However, deferral antileukemic therapy may be indicated to assess comorbidities or pre-therapeutic risk factors. We explored the impact time from diagnosis on outcomes in leukemia undergoing venetoclax-based two distinct cohorts. By querying Study Alliance Leukemia database and health network TriNetX, we identified 138 717 patients respectively with an average age 76 72...