A5067674096- DNA Repair Mechanisms
- Carcinogens and Genotoxicity Assessment
- CAR-T cell therapy research
- Cancer Immunotherapy and Biomarkers
- Molecular Biology Techniques and Applications
- DNA and Nucleic Acid Chemistry
- Antimicrobial Resistance in Staphylococcus
- Radiation Therapy and Dosimetry
- Cancer Research and Treatments
- Immunotherapy and Immune Responses
- Genomics and Chromatin Dynamics
- Radiopharmaceutical Chemistry and Applications
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Antibiotic Resistance in Bacteria
- Advanced biosensing and bioanalysis techniques
- Innovative Microfluidic and Catalytic Techniques Innovation
- Chromosomal and Genetic Variations
- Bacteriophages and microbial interactions
- PARP inhibition in cancer therapy
- Antifungal resistance and susceptibility
- Bacterial biofilms and quorum sensing
- Oral microbiology and periodontitis research
- bioluminescence and chemiluminescence research
- Effects of Radiation Exposure
Theravance Biopharma (United States)
2019-2024
Sri Devaraj Urs Medical College
2020-2024
Sri Devaraj Urs Academy of Higher Education and Research
2020-2024
Creative Commons
2023
Kasturba Medical College, Manipal
2021
Manipal Academy of Higher Education
2021
Indira Gandhi Medical College and Research Institute
2014
National Institute of Mental Health and Neurosciences
2008
University of Minnesota
1998-2002
Biotechnology Institute
2002
For direct and on-line study of the physiological states cell cultures, a robust flow injection system has been designed interfaced with cytometry (FI-FCM). The core includes microchamber for sample processing. design this allows not only an accurate dilution but also fixation, staining, washing. part was tested by monitoring optical density growing E.coli culture using spectrophotometer. entire growth curve, from lag phase to stationary phase, obtained frequent sampling. performance FI-FCM...
Journal Article Dose Assessments by Cytogenetic Analysis in the Goiania (Brazil) Radiation Accident Get access A.T. Ramalho, Ramalho Search for other works this author on: Oxford Academic PubMed Google Scholar A.C.H. Nascimento, Nascimento Natarajan Protection Dosimetry, Volume 25, Issue 2, 1 October 1988, Pages 97–100, https://doi.org/10.1093/oxfordjournals.rpd.a080358 Published: 01 1988
Autologous therapeutic tumor-infiltrating lymphocyte (TIL) therapy is a promising strategy to enhance antitumor immunity. Optimization of ex vivo TIL expansion could expand current immunotherapy options. Previous attempts generate in renal cell carcinoma (RCC) have been technically challenging. We applied second-generation manufacturing process, currently used the melanoma product lifileucel, RCC. Resected primary and metastatic RCC samples were processed using Gen 2 process comprising...
The influence of inhibitors poly(ADP-ribose) polymerase such as 3- aminobenzamide (3AB) and benzamide (B) on the spontaneously occurring well mutagen induced chromosomal aberrations, sister chromatid exchanges (SCEs) point mutations has been studied. In addition, we have measured 3AB DNA repair following treatment with physical chemical mutagens. Post X-irradiated mammalian cells increases frequencies aberrations by a factor 2 to 3. Both acentric fragments increase indicating that presence...
Trade-offs in catalytic efficiency at the lac permease of Escherichia coli produce alleles with different substrate specializations that are selectively favored on galactosides. We show differential resource utilization during competition for mixtures galactosides produces frequency-dependent selection lac. However, polymorphism is protected only a narrow range galactoside ratios despite intense pure Hence, stabilizing protecting natural allozyme polymorphisms through will be sporadic and...
We report a case of cerebral phaeohyphomycosis caused by Scytalidium dimidiatum (synanamorph Nattrassia mangiferae) in young, apparently immunocompetent Indian male. Etiological diagnosis was made recovery the fungus culture and histopathological examination. The infection proved fatal despite aggressive antifungal therapy.
AT cells are known to be more sensitive than normal human ionizing radiation as well other agents, judged by cell survival, induced chromosomal aberrations, and micronuclei. The inhibition of DNA replication following X-irradiation is less in cells. Four different lines heterozygous for were investigated their response various treatments order see whether they behaved an intermediate way. In most the tests, like frequencies aberrations X-rays, there was heterogeneity response, with one line...
The Algerian hedgehog <i>(Aethechinus</i>) has a diploid chromosome number of 48, similar to the European species <i>(Erinaceus</i>) and long-eared Asiatic hedgehog. There are, however, differences in size structure individual chromosomes. As compared with hedgehogs, which display three large blocks distally located autosomal constitutive heterochromatin, there are only two such segments They characterized by following properties, some may apply heterochromatin...
Background: In Chronic Suppurative Otitis Media (CSOM), the spread of micro organisms to adjacent structures can result in a broad range intracranial and extracranial complications. Objectives: To study microbiological profile Materials Methods : Ear swabs were collected cultured from 200 patients with purulent discharge perforated tympanic membranes attending ENT clinic. The isolated identified by standard methods antibiogram pattern was determined. Results: most common organism Pseudomonas...
Summary. Thirty‐five patients with severe aplastic anaemia (SAA) were extensively evaluated 0.3‐12.4 years (median 3.8) after anti‐thymocyte globulin (ATG) treatment. All but one transfusion independent. Most revealed a normal Hb level and granulocyte count over 1.5 × 10 9 /1 still thrombocytopenic due to decreased platelet production. Lymphocytopenia and/or monocytopenia was found in about 30%. Two had monocytosis. Although there great range degree of recovery at various time intervals ATG....
Introduction Amputations and recurrent infections are two terrible outcomes of open fractures that can leave patients with permanent impairments. Rapid effective treatment protect from fracture sequelae the long-term financial burden these injuries frequently cause. Over 50% caused by high energy trauma, which most happens in car accidents or severe falls. There hasn't been much research done on first bacterial ecology wounds Indian environment. Therefore, need current assignment was to...
Introduction: Microbial keratitis poses a significant threat to vision and is common ocular infection. Its causative agents encompass wide spectrum, including bacteria, fungi, viruses, parasites. The microbiological profile of microbial influenced by factors such as patient demographics, geographical location, climate, occupational hazards evolves over time. Methodology: Corneal scrapings were collected from 75 patients with provisional diagnosis keratitis. samples processed in the...
Fluorescence in situ hybridisation (FISH) with chromosome-specific composite DNA probes, has been shown to be a valid method for quantifying structural stable chromosome rearrangements (translocations) human lymphocytes. The inherent stability of translocations over cell generations enabled them used as biodosemeter. objectives the present work are current state knowledge on use FISH biological dosimetry and design future direction validate technique further. Experiments were designed...
Retrospective Biological Dosimetry of Absorbed Radiation Get access B. S. Rao, Rao Search for other works by this author on: Oxford Academic PubMed Google Scholar A. T. Natarajan Protection Dosimetry, Volume 95, Issue 1, 1 May 2001, Pages 17–23, https://doi.org/10.1093/oxfordjournals.rpd.a006516 Published: 01 2001