A5021795570- Psychosomatic Disorders and Their Treatments
- Medical Practices and Rehabilitation
- Mental Health and Psychiatry
- Psychotherapy Techniques and Applications
- Personality Disorders and Psychopathology
- Musculoskeletal pain and rehabilitation
- Trauma and Emergency Care Studies
- Musculoskeletal Disorders and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Medical and Health Sciences Research
- Child Abuse and Trauma
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Neural dynamics and brain function
- Total Knee Arthroplasty Outcomes
- Biomedical and Chemical Research
- Tryptophan and brain disorders
- Posttraumatic Stress Disorder Research
- Treatment of Major Depression
- Cancer Diagnosis and Treatment
- Trauma Management and Diagnosis
- BRCA gene mutations in cancer
- Psychiatric care and mental health services
- Muscle metabolism and nutrition
Otto-von-Guericke University Magdeburg
2016-2025
Federal Institute for Drugs and Medical Devices
2023-2024
University Hospital Magdeburg
2021-2023
Klinikum Magdeburg
2022-2023
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2004-2021
Helmholtz-Zentrum Berlin für Materialien und Energie
2021
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
2017
University of Siegen
2016
University of Rostock
2010-2012
Universitätsmedizin Rostock
2011
To determine the frequency, mutation spectrum and phenotype of recently described autosomal recessive MUTYH-associated polyposis (MAP), we performed a systematic search for MUTYH (MYH) mutations by sequencing complete coding region gene in 329 unselected APC mutation-negative index patients with clinical diagnosis familial adenomatous (FAP) or attenuated FAP (AFAP). Biallelic germline were identified 55 (17%) another 9 selected cases. About one-fifth (20%) 64 unrelated MAP harboured none 2...
Der Begriff der Dissoziation wurde in frühen Anfängen Neurosenlehre verwendet, hat sich seither gewandelt und ist Ausgangspunkt vieler Kontroversen. Unter wird i. Allg. die Abspaltung sonst integrierter Gedächtnis‑, Bewusstseins‑, Identitäts- Wahrnehmungsfunktionen (eigene Person Umwelt) verstanden. ein klinisches Kriterium von Belastungsstörungen emotional instabilen Persönlichkeitsstörung; dissoziative Symptome haben sind ebenfalls als Phänomene bei anderen Erkrankungen hochrelevant....
Abstract Dysfunctions in bottom‐up emotion processing (EP), as well top‐down regulation (ER) are prominent features pathophysiology of major depressive disorder (MDD). Nonetheless, it is not clear whether EP‐ and ER‐related areas regionally and/or connectively disturbed MDD. In addition, yet to be known how interactively linked regulatory behavior, this interaction disrupted our study, regional amplitude low frequency fluctuations (ALFF) whole‐brain functional connectivity (FC)...
Systematic doping programs like in the GDR were applied adolescent competitive athletes to induce supramaximal athletic performance. The substances had adverse somatic and psychological effects. development of young was impaired they suffered adulthood from long-term effects secondary diseases even years after period.
Previous studies found an elevation of the dopamine D<sub>3</sub> receptor (DRD3) mRNA as determined in peripheral lymphocytes schizophrenic patients. The aim this study was to test hypothesis elevated DRD3 schizophrenia compared bipolar disorder. Twenty-four patients, 13 and 11 bipolar, were included according DSM-IV criteria. Psychometric measures conducted using Scale for Assessment Positive Symptoms, Negative Brief Psychiatric Rating Scale, Montgomery-Åsberg Depression Young...
<i>Background:</i> Dissociation is often related to previous trauma and also occurs frequently in schizophrenia. psychosis may reflect a posttraumatic syndrome some patients with <i>Sampling Methods:</i> In total, 80 diagnosed schizophrenia were investigated by means of the Childhood Trauma Questionnaire (CTQ), Dissociative Experience Scale Symptom Check List 90-R. CTQ subscales groups reporting high low dissociation compared using MANOVA. <i>Results:</i>...
People presenting to centres for rare diseases (CRD) diagnostic work-up often suffer from mental disorders. The prevalence and distribution of these disorders their relevance care remain largely unclear well-controlled multicentre studies are missing. ZSE-DUO study was a multicentre, prospective, controlled cohort involving 11 German CRD. In total, 662 adult patients with an diagnosis were evaluated by additional health specialist along usual CRD care. Mental assessed through standardized...
To explain the phenomenological overlap between dissociation and schizophrenia, a dissociative subtype of schizophrenia has been proposed as possibility. Dissociation is often believed to be organized on continuum, although 2 qualitatively different phenomena can distinguished in theory, research, clinical practice: (a) states separation from self or environment (detachment dissociation) (b) inaccessibility normally accessible mental contents (compartmentalization dissociation). This study...
Background . Type D personality (TDP) is a sign of tapered stress and compromises treatment outcomes including those hip arthroplasty. The common dissatisfaction with total knee arthroplasty (TKA) predicted by fear avoidance, pain catastrophizing emotional lability, poor quality life (QoL) reflecting these strains. This study the first to investigate influence TDP on TKA assuming (1) negative affect (NA) be linked avoidance increased (2) expression NA social inhibition (SI) not stable over...
<i>Background:</i> To investigate the relationship between dissociative experiences, psychopathological distress, a history of trauma and posttraumatic symptoms in adult schizophrenia. <i>Methods:</i> Eighty-seven schizophrenic inpatients returned self-questionnaires [Dissociative Experience Scale (DES); Symptom Checklist (SCL-90-R); PTSD (PDS)]. Based upon this self-rating, 14 participants fulfilled cut-off definition according to DSM-IV criteria, 43 had without...
The basic idea of business process modeling is to identify the set activities which has be performed reach a particular goal and define partial order on that set. A mobile instances where individual are using computer like PDA or smartphone. contribution this paper introduction special approach for such processes, based Business Process Modeling Notation (BPMN). Our modelling includes so called location constraints can assigned BPMN diagram. Such constraint makes statement about activity not...
Recently there is a growing psychotraumatological interest in late life effects former German warchildren. The following article focusses on kind and amount of trauma psychopathology (Symptom Check List 90-R; SCL-90-R) elderly people, who have grown up during World War II. By means psychometric self-reports we assessed their current interpersonal problems (Inventory Interpersonal Problems; IIP), the quality (SF-36 Health Survey) sense coherence (Antonovsky's Sense coherence-Scale; SOC)....
Artificial intelligence (AI) in the fourth industrial revolution is a key building block and becoming more significant as digitization increases.AI implementation enterprises increasingly focused on technological economic aspects, disregarding human factors. In this context, success of AI technologies depend employee acceptance. Low adoption can lead to poorer performance well dissatisfaction. To ensure expected added value through AI, it necessary for companies increase People see machine...
Brain investigations identified salience network (SN) comprising the dorsal Anterior Cingulate Cortex (dACC) and Insula (AI). Magnetic resonance spectroscopy (MRS) studies revealed link between glutamate concentration in ACC alterations attentional scope. Hence, we investigated whether dACC modulates brain response during processing.Twenty-seven healthy subjects (12♀, 15♁) provided both STEAM MRS at 7T measuring concentrations as well a functional magnetic imaging (fMRI) task to study...
BackgroundPeople with complex symptomatology but unclear diagnosis presenting to a centre for rare diseases (CRD) may present mental (co-)morbidity. We hypothesised that combining an expert in somatic medicine health specialist working tandem will improve the diagnostic outcome.MethodsPatients aged 12 years and older who presented one of 11 participating German CRDs unknown were recruited into this prospective cohort trial two-phase design. From October 1, 2018 September 30, 2019,...