A5042679217- Prenatal Screening and Diagnostics
- Genomic variations and chromosomal abnormalities
- Fetal and Pediatric Neurological Disorders
- Scottish History and National Identity
- Financial Crisis of the 21st Century
- Archaeological Research and Protection
- Linguistics and Cultural Studies
- Historical Influence and Diplomacy
- Olfactory and Sensory Function Studies
- Genomics and Rare Diseases
- Autism Spectrum Disorder Research
- Historical Geography and Cartography
- BRCA gene mutations in cancer
- Advanced Chemical Sensor Technologies
Erasmus University Rotterdam
2014-2024
Erasmus MC
2017-2018
Genomic array detects more pathogenic chromosome aberrations than conventional karyotyping (CK), including genetic variants associated with a susceptibility for neurodevelopmental disorders; loci (SL). Consensus regarding the scope of invasive prenatal diagnosis (PND) pregnant couples should be offered is lacking. This study examined couples' preferences, doubts and satisfaction PND. Eighty‐two choosing screening (PNS) 59 PND were choice between 5 (comparable to CK) 0.5 Mb resolution...
Genomic microarray may detect susceptibility loci (SL) for neurodevelopmental disorders such as autism and epilepsy, with a yet unquantifiable risk the fetus. The prenatal disclosure of is topic much debate. Many health care professionals fear that reporting put psychological burden on pregnant couples. It our policy to disclose we recognize them actionable prospective parents. aim this report was evaluate impact disclosing diagnosis loci. evaluated in first patients who received results....
Developments in prenatal testing allow the detection of more findings. SNP arrays diagnosis (PND) can be analyzed at 0.5 Mb resolution detecting clinically relevant anomalies, or 5 resolution. We investigated whether women had sufficient knowledge to make informed choices regarding scope their test that were consistent with attitude. Pregnant could choose between array. Consenting (N = 69) received pre-test genetic counseling by phone and filled out Measure Informed Choice questionnaire...
Stefano Menini, Teresa Paccosi, Sara Tonelli, Marieke Van Erp, Inger Leemans, Pasquale Lisena, Raphael Troncy, William Tullett, Ali Hürriyetoğlu, Ger Dijkstra, Femke Gordijn, Elias Jürgens, Josephine Koopman, Aron Ouwerkerk, Sanne Steen, Inna Novalija, Janez Brank, Dunja Mladenic, Anja Zidar. Proceedings of the 3rd Workshop on Computational Approaches to Historical Language Change. 2022.
A 1508 adage by Erasmus about the Batavian ear is often interpreted as an expression of nationalism. Serious doubts can be raised against such interpretations since there was no thing nationalism in early sixteenth century. Besides this, interpretation inconsistent with Erasmus's degenerative expressions Batavians and Hollanders elsewhere; nor does describe or a truly positive way. I propose alternative to nationalistic adage. Based on Auris Batava, his correspondence, rest broad oeuvre,...
Abstract The unique collection of Erasmiana in the Rotterdam Public Library has a long history which there been varying attention to acquisition, preservation and presentation. This article describes how individuals such as donors, directors curators developed since it was first mentioned 1868. development is reconstructed through archival sources year reports, newspaper articles material evidence itself. From this reconstruction, possible distinguish three phases Erasmus Collection treated...
Our lab in Rotterdam has completely replaced conventional karyotyping (CK) by genomic array for nearly all indications prenatal diagnosis since July 2012, including an increased risk Down's syndrome. We prefer over CK because detects more clinically relevant anomalies. However, also genetic anomalies of yet unquantified mostly neuro-developmental disorders, so-called susceptibility loci (SL). conducted this study to assess pregnant couples' preferences and how being offered a choice...