- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Morinda citrifolia extract uses
- Eicosanoids and Hypertension Pharmacology
- Cholesterol and Lipid Metabolism
- Analytical Chemistry and Chromatography
- Natural Antidiabetic Agents Studies
- Chromatography in Natural Products
- Pharmacological Effects of Natural Compounds
- Inflammatory mediators and NSAID effects
Mexican Social Security Institute
2017-2018
Universidad Autónoma Metropolitana
2014
Centro Científico Tecnológico Mar del Plata
2014
Sechium edule is traditionally used in Mexico as a therapeutic resource against renal diseases and to control high blood pressure. The purpose of this work evaluate the antihypertensive effect hydroalcoholic extract obtained from roots plant, including its fractions subfractions, on different hypertension models induced with angiotensin II (AG II). was tested an vitro study isolated aorta rings denuded endothelial cells, using AG agonist; assay proved vasorelaxant extract. Vagotomized rats...
Hypertension is a disease of high prevalence and morbidity where vascular inflammation associated oxidative stress (endothelial dysfunction) the underlying cause this pathology. We are reporting antihypertensive activity extracts fractions Malva parviflora in mice with chronic acute hypertension. Also, treatments plant were able to counteract kidney stress. The hypertension model consisted administration angiotensin II (AGII) during 12 weeks, causing sustained increase systolic (SBP) or...
An anxiolytic fraction of Tilia americana standardized in tiliroside, rutin, quercitrin, quercetin glucoside, and kaempferol was obtained. After oral administration the fraction, above-mentioned flavonoids were not detected plasma over 24 h. However, meta para hydroxyphenylacetic acid dihydroxyphenylacetic (m-HPAA, p-HPAA DOPAC) monitored. These are biotransformation compounds aglycones quercetin; these products other present fraction. The analytical methods (HPLC) for related validated,...
Endothelial dysfunction induced by Angiotensin II (AG II) plays an important role in the pathogenesis of hypertension and is accompanied a prooxidative condition, which turn induces inflammatory state, vascular remodeling, tissue damage including kidney (Schmitt Dirsch, 2009) [1]. New drugs that can control several these pathologies are required. Sechium edule has been reported to possess antioxidant, anti-inflammatory antihypertensive activity (Ibarra-Alvarado et al., 2010) [2]. This paper...