A5046743644- Birth, Development, and Health
- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Gestational Diabetes Research and Management
- Genomics and Phylogenetic Studies
- Per- and polyfluoroalkyl substances research
- Molecular Biology Techniques and Applications
- Invertebrate Immune Response Mechanisms
- Plant tissue culture and regeneration
- Cancer, Hypoxia, and Metabolism
- Allelopathy and phytotoxic interactions
- Plant Parasitism and Resistance
- Liver Disease Diagnosis and Treatment
- Gene expression and cancer classification
- Insect Resistance and Genetics
- Physiological and biochemical adaptations
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- Horticultural and Viticultural Research
- Liver Disease and Transplantation
- Diet and metabolism studies
- Insect and Arachnid Ecology and Behavior
- Nutrition and Health in Aging
- Seaweed-derived Bioactive Compounds
- Marine Bivalve and Aquaculture Studies
Chinese University of Hong Kong
2020-2024
Prince of Wales Hospital
2022
University of the Philippines Diliman
2018
Abstract Non-alcoholic fatty liver disease (NAFLD) has emerged as the most prevalent chronic worldwide, yet detection remained largely based on surrogate serum biomarkers, elastography or biopsy. In this study, we used a total of 2959 participants from UK biobank cohort and established association dual-energy X-ray absorptiometry (DXA)-derived body composition parameters leveraged machine learning models to predict NAFLD. Hepatic steatosis reference was MRI-PDFF which been extensively...
This is the first study using transcriptome and 16S rRNA gene sequencing to report hypotonic responsive genes in gill cells compositions of microbiota marine medaka. The overlapped glycosaminoglycan- chitin-related pathways suggest host-bacterium interaction fish during osmotic stress.
Abstract Food security is important for the ever-growing global population. Soybean, Glycine max (L.) Merr., cultivated worldwide providing a key source of food, protein and oil. Hence, it imperative to maintain or increase its yield under different conditions including challenges caused by abiotic biotic stresses. In recent years, soybean pod-sucking stinkbug Riptortus pedestris has emerged as an agricultural insect pest in East, South Southeast Asia. Here, we present genomics resource R....
We examined the changes in hepatic metabolic gene expression and gut microbiota of offspring exposed to PFOS in-utero. At GD17.5, our data showed that exposure decreased fetal bodyweights expressions but increased relative liver mass lipid accumulation. PND21, in-utero high-dose PFOS-exposed exhibited significantly greater bodyweight (catch-up-growth), associated with significant induction expression. In addition, 16SrRNA-sequencing cecal samples revealed an increase carbohydrate catabolism...
Abstract Structural variations (SVs) are commonly found in cancer genomes. They can cause gene amplification, deletion and fusion, among other functional consequences. With an average read length of hundreds kilobases, nano-channel-based optical DNA mapping is powerful detecting large SVs. However, existing SV calling methods not tailored for samples, which have special properties such as mixed cell types sub-clones. Here we propose the Cancer Optical Mapping Variations (COMSV) method that...
The fish gill is the first tissue that exposed to external media and undergoes continuous osmotic challenges. Recently, our group published an article entitled "Integrated Omics Approaches Revealed Osmotic Stress-Responsive Genes Microbiota in Gill of Marine Medaka" journal mSystems (e0004722, 2022), suggested possible host-bacterium interaction during stress. previous study was performed by progressive fresh water transfer (i.e., seawater via 50% (FW)). Our hypothesized gradient could be a...
Abstract Structural variations (SVs) are commonly found in cancer genomes. They can cause gene amplification, deletion, and fusion, among other functional consequences. With an average read length of hundreds kilobases, nano-channel-based optical DNA mapping is powerful detecting large SVs. However, existing SV calling methods not tailored for samples, which have special properties such as mixed cell types sub-clones. Here we propose the COMSV method that specifically designed samples. It...
We examined the changes of hepatic metabolic gene expression and gut microbiota offspring, exposed to PFOS in-utero. At GD17.5, our data showed that PFOS-exposure decreased fetal bodyweights expressions, but increased relative liver mass lipid accumulation. PND21, in-utero high-dose PFOS-exposed offspring exhibited significant greater bodyweight (catch-up-growth), associated with induction expression. In addition, 16SrRNA-sequencing cecal samples revealed an increase in carbohydrate...