Among the shades! With respect to its availability, low toxicity, and price, iron should be one of most used metals in homogeneous catalysis. Surprisingly, so far application is underdeveloped comparison with other transition metals. Some promising attempts obtained redox reactions coupling chemistry which nicely illustrate potential hopefully initialize a ferric future for catalysis are highlighted.

Abstract Borrowing hydrogen (or autotransfer) reactions represent straightforward and sustainable C–N bond-forming processes. In general, precious metal-based catalysts are employed for this effective transformation. recent years, the use of earth abundant cheap non-noble metal process attracted considerable attention in scientific community. Here we show that selective N -alkylation amines with alcohols can be catalysed by defined PNP manganese pincer complexes. A variety substituted...

Hydrogenations constitute fundamental processes in organic chemistry and allow for atom-efficient clean functional group transformations. In fact, the selective reduction of nitriles, ketones, aldehydes with molecular hydrogen permits access to a green synthesis valuable amines alcohols. Despite more than century developments homogeneous heterogeneous catalysis, efforts toward creation new useful broadly applicable catalyst systems are ongoing. Recently, Earth-abundant metals have attracted...

With respect to its availability, low toxicity, and price iron should be one of the most used metals in homogeneous catalysis. Surprisingly, so far application is underdeveloped comparison other transition metals. Herein, we highlight promising attempts obtained hydrogenation, transfer hydrogenation hydrosilylation, which nicely illustrate potential hopefully initialize a ferric future for

Ende des Schattendaseins? Die leicht verfügbaren, kaum toxischen und billigen Eisenverbindungen bieten sich für die homogene Katalyse an, ihr Anwendungsbereich ist überraschenderweise aber deutlich geringer als bei anderen Übergangsmetallen. Dieses Highlight fasst einige vielversprechende Ansätze aus der Redox- Kupplungschemie zusammen, das Potenzial von Eisenkatalysatoren unterstreichen.

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTCatalytic Hydrogenation of Carboxylic Acid Esters, Amides, and Nitriles with Homogeneous CatalystsSvenja Werkmeister, Kathrin Junge, Matthias Beller*View Author Information Leibniz-Institute for Catalysis, Albert-Einstein-Straße 29a, 18059 Rostock, Germany*E-mail: [email protected]Cite this: Org. Process Res. Dev. 2014, 18, 2, 289–302Publication Date (Web):January 13, 2014Publication History Received15 November 2013Published online2 February...

A novel zinc-catalyzed reduction of tertiary amides was developed. This system shows remarkable chemoselectivity and substrate scope tolerating ester, ether, nitro, cyano, azo, keto substituents.

The first well-defined iron-based catalyst system for the reduction of nitroarenes to anilines has been developed applying formic acid as reducing agent. A broad range substrates including other reducible functional groups were converted corresponding in good excellent yields at mild conditions. Notably, process constitutes a rare example base-free transfer hydrogenations.

Abstract In the last decade, an increasing number of useful catalytic reductions carboxylic acid derivatives with hydrosilanes have been developed. Notably, combination appropriate silane and catalyst enables unprecedented chemoselectivity that is not possible traditional organometallic hydrides or hydrogenation catalysts. For example, amides esters can be reduced preferentially in presence ketones even aldehydes. We believe hydrosilylations will used more often future challenging organic...

Pincer complexes are becoming increasingly important for organometallic chemistry and organic synthesis. Since numerous applications such catalysts have been developed in recent decades, this Minireview covers progress their use as (de)hydrogenation transfer reactions during the last four years. Aside from noble-metal-based pincer complexes, corresponding base metal also highlighted summarized.

Base‐metal catalysis, especially with non‐noble‐metal pincer‐type catalysts, is increasingly used in organic synthesis and thus becoming more important for organometallic chemistry. After ruthenium‐, iridium‐ iron‐based complexes became established as state‐of‐the‐art catalysts (de)hydrogenation reactions the past decade, manganese have most recently been successfully applied related transformations. Specifically, this microreview covers their recent progress transfer well C–C C–X...

Abstract We present the first base‐free Fe‐catalyzed ester reduction applying molecular hydrogen. Without any additives, a variety of carboxylic acid esters and lactones were hydrogenated with high efficiency. Computations reveal an outer‐sphere mechanism involving simultaneous hydrogen transfer from iron center ligand. This assumption is supported by NMR experiments.

An important goal for nanocatalysis is the development of flexible and efficient methods preparing active stable core-shell catalysts. In this respect, we present synthesis characterization iron oxides surrounded by nitrogen-doped-graphene shells immobilized on carbon support (labeled FeOx@NGr-C). Active catalytic materials are obtained in a simple, scalable two-step method via pyrolysis acetate phenanthroline subsequent selective leaching. The optimized FeOx@NGr-C catalyst showed high...

While the iron is hot: The first general and efficient iron-catalyzed reduction of secondary tertiary amides into amines using polymethylhydrosiloxane (PMHS) has been developed (see scheme). Detailed facts importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by authors. Please note: publisher responsible for content functionality any supporting information supplied Any queries...

Abstract The first manganese‐catalyzed hydrogenation of esters to alcohols has been developed. combination Mn(CO) 5 Br with [HN(CH 2 CH P(Et) ) ] leads a mixture cationic and neutral Mn PNP pincer complexes, which enable the reduction various ester substrates, including aromatic aliphatic as well diesters lactones. Notably, related complexes isopropyl or cyclohexyl substituents showed very low activity.

Put a label on it: Carbon dioxide with H2 is shown to be an efficient and selective methylation reagent for aromatic aliphatic amines (see scheme; acac=acetylacetonate, triphos = 1,1,1-tris(diphenylphosphanylmethyl)ethane). A variety of functionalized including 13C-labelled drugs were obtained good yields functional-group tolerance. As service our authors readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed may re-organized online...

Control with an iron hand: A broad range of ketimines underwent enantioselective hydrogenation in the presence a chiral Brønsted catalyst and well-defined nonchiral (see scheme). This procedure constitutes attractive environmentally favorable alternative to well-established asymmetric reactions precious-metal catalysts.

Putting CO2 to work: Carbon dioxide is shown be a general and selective methylating reagent for secondary primary, aromatic aliphatic amines under reductive conditions. A variety of tertiary are obtained from commercially available silanes in high yields with good tolerance nitrile, olefin, ether, ester, hydroxy groups.

Cobalt oxide/cobalt-based nanoparticles featuring a core-shell structure and nitrogen-doped graphene layers on alumina are obtained by pyrolysis of Co(OAc)2/phenanthroline. The resulting material (Co3O4-Co/NGr@α-Al2O3) was successfully applied in the catalytic hydrogenation variety N-heteroarenes including quinolines, acridines, benzo[h], 1,5-naphthyridine as well unprotected indoles. peculiar novel heterogeneous catalyst enables activation molecular hydrogen at comparably low temperature....

Developing new synthetic approaches for benign CO2 utilization is of current interest. In this respect, reductive alkylations using N- or C-based nucleophiles to give the corresponding methyl amines and (hetero)arenes are investigated intensively. Crucial points such methylations choice suitable homogeneous heterogeneous catalyst systems. article, selective activation substrates use acidic cocatalysts highlighted.