Dulshara Sachini Amarasekara

ORCID: 0000-0001-7085-0682
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About
Contact & Profiles
Research Areas
  • Bone Metabolism and Diseases
  • Disaster Management and Resilience
  • Cytokine Signaling Pathways and Interactions
  • Bone health and treatments
  • Disaster Response and Management
  • Maternal Mental Health During Pregnancy and Postpartum
  • Vitamin D Research Studies
  • Malaria Research and Control
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Retinoids in leukemia and cellular processes
  • Viral Infections and Outbreaks Research
  • Inflammatory Bowel Disease
  • Bird parasitology and diseases
  • Rabies epidemiology and control
  • Agricultural risk and resilience
  • Sperm and Testicular Function
  • Fluoride Effects and Removal
  • Immunodeficiency and Autoimmune Disorders
  • Cell Adhesion Molecules Research
  • Animal testing and alternatives
  • Flood Risk Assessment and Management
  • NF-κB Signaling Pathways
  • Stress Responses and Cortisol
  • Asthma and respiratory diseases
  • Animal Behavior and Welfare Studies

University of Colombo
2012-2025

University of Sri Jayewardenepura
2023

Sri Lanka Institute of Information Technology
2023

CINEC Campus (Pvt) Ltd.
2023

Chungnam National University
2016-2022

University of Minnesota
2015

Seminal oxidative stress plays an important role in male factor infertility (MFI), worldwide. A study was thus undertaken for the first time to establish seminal reactive oxygen species (ROS) as a clinical marker of MFI cohort Sri Lankan males. The nitro blue tetrazolium (NBT) assay ROS estimation and modified Endtz test detecting leucocytes were carried out on semen samples (N = 102) subfertile Age-matched individuals 30) with proven past paternity served controls. Significantly higher...

10.1111/and.12043 article EN Andrologia 2012-11-16

Postpartum depression is a severe emotional and mental disorder that involves maternal care defects psychiatric illness. closely associated with combination of physical changes physiological stress during pregnancy or after parturition in stress-sensitive women. Although postpartum relatively well known to have deleterious effects on the developing fetus, influence genetic risk factors development remains unclear. In this study, we discovered novel function T cell death-associated gene 51...

10.1371/journal.pgen.1008214 article EN cc-by PLoS Genetics 2019-06-28

Abstract Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, is a group of chronic inflammatory diseases the gastrointestinal tract. Although multifactorial etiology IBD pathogenesis relatively well documented, regulatory factors that confer risk remain less explored. In this study, we report T-cell death-associated gene 51 (TDAG51/PHLDA1) novel regulator development dextran sulfate sodium (DSS)-induced in mice. TDAG51 expression was elevated colon tissues...

10.1038/s41598-022-24873-4 article EN cc-by Scientific Reports 2022-11-30

Abstract Background Pediatric psoriasis accounts for nearly one‐third of the global burden. Multiple lines evidence have shown relationship between Angiotensin‐converting enzyme (ACE) Insertion (I)/deletion(D) polymorphism with susceptibility, and oxidative stress (OS) in psoriatic patients. However, such studies, particularly on pediatric psoriasis, are scarce local setting. Aims Our study investigated prevalence ACE I/D its associations patients Sri Lanka. Methods Thirty were recruited...

10.1002/hsr2.2309 article EN cc-by-nc-nd Health Science Reports 2024-09-01

The Journal of the National Science Foundation Sri Lanka publishes results research in all aspects and Technology. journal also has a website at http://www.nsf.gov.lk/. 2021 Impact Factor: 0.682The JNSF provides immediate open access to its content on principle that making freely available public supports greater global exchange knowledge.

10.4038/jnsfsr.v42i2.6999 article EN cc-by-nd Journal of the National Science Foundation of Sri Lanka 2014-06-10

This study sheds light on the less-researched areas of psycho-social issues faced by flood-affected residents, and conflicts arising among those according to government officials as key informants within Kalu river basin Sri Lanka. Here, a workshop was conducted in Kuruwita Divisional Secretariat (DS) with who deal floods area. First, individually answered questionnaire related impacts affected community. Second, group poster presentations were investigate during floods. Conflicts reported...

10.2139/ssrn.4527919 preprint EN 2023-01-01
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