- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Peripheral Neuropathies and Disorders
- Sexual function and dysfunction studies
- Amyotrophic Lateral Sclerosis Research
- Diet and metabolism studies
- Neurogenetic and Muscular Disorders Research
- Myasthenia Gravis and Thymoma
- Liver physiology and pathology
- Polyomavirus and related diseases
- Neuroscience and Music Perception
- Spinal Fractures and Fixation Techniques
- Antifungal resistance and susceptibility
- Music Therapy and Health
- Genetics and Neurodevelopmental Disorders
- Neurofibromatosis and Schwannoma Cases
- Glycosylation and Glycoproteins Research
- Tracheal and airway disorders
- Meningioma and schwannoma management
- Prion Diseases and Protein Misfolding
- Thyroid and Parathyroid Surgery
- Proteoglycans and glycosaminoglycans research
- Diverse Music Education Insights
- Infectious Diseases and Tuberculosis
- Neuroendocrine Tumor Research Advances
University Hospital Centre Zagreb
2019-2023
Coronavirus disease 2019 (COVID-19) vaccines have been reported as possible triggers of the production antibodies pathogenic to peripheral nerve and neuromuscular junction. We report on a patient who experienced vertical diplopia three weeks after booster dose Pfizer-BioNTech vaccine (Comirnaty®). The diagnosis myasthenia gravis (MG) was established based highly positive nicotinic acetylcholine receptor (nAChR). Treatment with pyridostigmine prednisone started gradually raising doses. On...
Risdiplam is an orally administered treatment for spinal muscular atrophy which leads to improvement in motor function as measured by functional scales compared with placebo. Although risdiplam has been registered since 2020, real-world data adults still scarce. There have no new safety signals so far, some results pointing that may be effectiveObjective:The objective was present of 31 adult patients type 2 and 3 treated the Republic CroatiaMethods:Treatment effects were assessed tests...
The extracellular matrix (ECM) is an important regulator of excitability and synaptic plasticity, especially in its highly condensed form, the perineuronal nets (PNN). In patients with drug-resistant mesial temporal lobe epilepsy (MTLE), hippocampal sclerosis type 1 (HS1) most common histopathological finding. This study aimed to evaluate ECM profile HS1 surgically treated MTLE correlation clinical findings. Hippocampal sections were immunohistochemically stained for aggrecan, neurocan,...
The aims were to determine the impact of dysphagia and glomerular filtration rate (GFR) in prediction myasthenia relapse analyse whether different number plasma exchange sessions could prolong time before future relapse.This was a retrospective, longitudinal follow-up study with 60 enrolled patients. patients followed-up for total 50 months.Patients without relapses had significantly higher GFR when compared relapses. Mean next longer ≥ mL/min. Time following symptoms dysphagia.Decline...
Introduction Avelumab is a programmed death ligand 1–blocking monoclonal antibody used for the treatment of Merkel cell carcinoma (MCC), urothelial carcinoma, and other solid tumors. It acts as an immune checkpoint inhibitor prolongs survival MCC patients. Immune-mediated neurological adverse effects are rare usually respond well to specific therapy. Methods Results A case 70-year-old man with metastatic described in this study. The patient developed diplopia after fourth dose avelumab,...