Pancreatitis, panniculitis, and polyarthritis (PPP) syndrome is a rare but serious disease that can be deadly. Its symptoms come on suddenly unexpectedly. This identified by erythematous bullous skin lesions arthritis caused pancreatic dysfunction. A 25-year-old man had an abdominal trauma with no past medical history. CT scan showed inflammation, peripancreatic edema, mild fluid in the head of pancreas without any collection blood retroperitoneum. The patient came back to hospital 2 weeks...

Introduction: COVID-19 has become a widespread epidemic worldwide. The different vaccines may play protective effect on illness intensity. Therefore, in this study, we aimed to evaluate measles IgG titer patients and correlate it with disease severity. Objectives: We evaluated the intensity of measles-specific immunoglobulin G (IgG) patients. Patients Methods: This cross-sectional study was conducted 72 infected high low An enzyme-linked immunosorbent assay (ELISA) used detect...

Background: Magnesium is one of the most abundant cations in body and plays a vital role function cardiovascular system. Hypomagnesemia can cause severe dangerous complications. Also, since drugs that lead to hypomagnesemia are commonly prescribed cardiac patients, we decided investigate prevalence population patients be aware this condition as an important risk factor for events. Materials Methods: This study retrospective cross-sectional analytical-observational type with...

Key Clinical Message Sarcoidosis is a systemic inflammatory disease able to affect any organ within the body. may be body's secondary response COVID‐19 infection and sign of rehabilitation. Early treatments reinforces this hypothesis. The majority sarcoidosis patients require immunosuppressive therapies, including corticosteroids. Abstract Most studies so far have focused on management in suffering from sarcoidosis. Nevertheless, current report aims present COVID‐19‐induced case. with...

Rhabdomyolysis was not reported in clinical trials with Sitagliptin alone. However, several reports the literature on rhabdomyolysis resulted from interaction between statins and Sitagliptin. In patients type 2 diabetes hyperlipidemia, it is expected to co-prescribe Herein, we report case of a 64-year-old woman should be caused by drug-drug Rosuvastatin The patient denied any history weakness or myalgia during past medical assessments.

Metabolic bone disorder is an abnormality of bones indicated by reduced mass and high risk fractures. Several lines evidence have demonstrated that the local tissue renin-angiotensin system (RAS) directly involved in metabolism influences health. This review aimed to assess role RAS comparative effectiveness angiotensin-converting enzyme inhibitors (ACEIs) angiotensin receptor blockers (ARBs) reducing In summary, clinical trials, vivo studies, functional - pharmacological experiments...

Abstract Adult onset still's disease (AOSD) is a rare autoinflammatory displaying with wide range of non‐specific symptoms and budd‐chiari syndrome (BCS) an uncommon disorder characterized by obstruction hepatic venous outflow. We present the case young patient who presented persistent fever, sore throat, elbow, hand fingers knees arthralgia abdominal pain. The patient's had started 7 days before referral. Imaging laboratory data led to diagnosis BCS in context AOSD. treated corticosteroid...

Hyperuricemia is described as a serum uric acid level more than 6.0 mg/dL. It demonstrated by basic research and clinical studies, which the elevation of may change renal histology function developing acute chronic kidney diseases (CKDs), diabetic nephropathy end-stage disease (ESRD). There no doubt about significant relationship between impairment. However, details this correlation, especially; failure, are discussable. Renal vasoconstriction, antiangiogenic properties, endothelial...

The renin-angiotensin-aldosterone system (RAAS) has a significant act in the pathology of blood pressure and cancer. One dominant sections angiotensin II (Ang II) angiotensin-converting enzyme (ACE) expression generation human body is capillary veins lung. Changes RAAS were revealed to be included several lung diseases. There are studies on anticancer effect ACE inhibitors; however, Hicks colleagues reported an augmented risk 14% for advancing cancer patients consuming inhibitors against...

Introduction: With the advent of COVID-19 pandemic, extensive efforts have begun worldwide to identify factors that reduce incidence disease. Various methods been launched combat Changes in serum immunoglobulin levels are among considered COVID-19. Objectives: The aim this study was determine changes IgG patients diagnosed with 2020 at Al-Zahra hospital Isfahan. Patients and Methods: In prospective study, 65 were evaluated. Their assessed before three six months after start treatment,...

Background: Coronavirus SARS-CoV-2 infection is associated with cardiovascular morbidity and mortality, even in individuals without pre-existing disease. Various types of arrhythmias have been reported COVID-19 patients, including bradycardia, although its relationship to mortality remains unclear. Objectives: This study aimed present a case series patients bradyarrhythmia examine factors mortality. Methods: In this series, we 50 confirmed who developed significant sustained bradycardia...

Introduction: COVID-19 is associated with a cascade of inflammatory responses potentially lead to devastating outcomes. Objectives: The current study aims investigate the efficacy montelukast, leukotriene receptor antagonist (LTRA), on laboratory parameters in infection. Patients and Methods: randomized clinical trial (RCT) conducted 67 patients moderate-to-severe pneumonia 2020-2021. All received treatments according national guidelines, while case group additionally applied 10 mg...

This study investigates the impact of omeprazole on urinary magnesium (Mg) excretion in children undergoing treatment for peptic disease. Specifically, it examines how influences fractional Mg. single-arm clinical trial was conducted from 2020 to 2021. With 44 diagnosed with acid disease who received (1-2 mg/kg/day) 3 months at Gastroenterology Clinic Imam Hossein Hospital, Isfahan, Iran. Serum and urine levels Mg creatinine were measured before after intervention using Pars Azmoon Kit,...

In this study, we considered an 83-year-old male patient admitted to the Al-Zahra hospital emergency department in Isfahan. He complained of fatigue, weakness, headache, and cough. addition, he had hallucinations delusions for two days; but no fever chill. His physical examination showed a blood pressure 170/100 mm Hg, heart rate 142 beats per minute (bpm), respiratory 23 pbm, oxygen saturation (in room air) 83%, bag reserve mask 93%. We realized cardiac involvement during hospitalization,...

Objective: Aluminum phosphide (ALP) and zinc (ZnP) are toxic agrochemical pesticides, which commonly used as an agent of self-harm in developing countries. Because high toxicity phosphides, we evaluated toxico-epidemiology ALP ZnP poisoning with respect to outcome. Methods: We performed a cross-sectional study retrospective chart review including the records for patients admitted due (ALP, ZnP) referral center Khorshid Hospital, affiliated Isfahan University Medial Sciences, Isfahan, Iran....

The treatment of ventilator-associated pneumonia (VAP) caused by carbapenem-resistant Acinetobacter baumannii (CRAB) is still a great challenge. This study evaluated the effectiveness colistin/levofloxacin regimen compared to usual colistin/meropenem in patients with VAP CRAB.The were randomly assigned experimental (n = 26) and control 29) groups. first group received IV colistin 4.5 MIU every 12 h + levofloxacin 750 mg daily, second same dose meropenem 1 g 8 for 10 days. clinical (complete...

This case report aims to introduce a patient with severe hypokalemia as one of the rare complications ondansetron injection. The stroke was 56 years old and hospitalized in emergency department purulent sputum. symptoms lung computed tomography scan confirmed diagnosis aspiration pneumonia. A nasogastric tube inserted, food gavage performed for patient. treatment started meropenem manage could not tolerate gavage. Consequently, prescribed, but 2.5 mEq/l developed. causes were evaluated....

Vascular endothelial growth factor (VEGF) is a special mitogen for vascular cells, an essential endogenous angiogenic cytokine, and the principal controller of that plays fundamental role in therapeutic angiogenesis pathways. VEGF-targeted therapy categorized into group inhibitors inhibit expression or activity VEGF. It comprises counteracting VEGF antibodies, receptors, VEGF-trap, tyrosine kinase inhibitor (TKIs) with selectivity receptors. The kidney both target source may be vital...

Amphotericin B is an antifungal agent used to treat serious fungal infections mainly in critically ill patients. Despite its adverse effects including renal toxicity and electrolyte imbalances, amphotericin remains one of the best choices for treatment. Information from animal studies has provided a strong scientific basis use pentoxifylline as lowering nephroprotective agent. The present study was designed evaluate efficacy preventing electrolytes imbalances induced by B.This conducted...

COVID-19 is a newly emerging infectious disease which first described in December 2019 Wuhan, China. The rapidly spread through the world and after short time of emerging, World Health Organization (WHO) declared as pandemic. Since, respiratory system main organ affected by COVID-19, kidney could be involved well. Given importance involvement this study we tried to evaluate describe effect severe acute syndrome coronavirus 2 (SARS-CoV-2) on kidney.

Introduction: Hypertension is one of the most common diseases and main cause disability mortality worldwide. Hyperuricemia has been recognized as causes hypertension; however, few studies have conducted to determine correlation between serum uric acid reduction blood pressure changes. Objective: This study aimed assess acid-reduction changes in a group hemodialysis patients. Patients Methods: descriptive-analytical was on 21 patients taking allopurinol for first time. Serum acid, systolic...

Introduction: Ineffective esophageal motility (IEM) is an disorder (EMD) and the most prevalent abnormality routinely observed in manometry. Objectives: In this study, we investigated clinical characteristics of IEM patients effects proton pump inhibitors (PPI) surgical treatments on their conditions. Patients Methods: This cross-sectional study was conducted Isfahan 2019-2020 40 diagnosed with IEM. We collected patient demographic information (age, gender, previous medical history,...