A5015665284- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Animal Nutrition and Physiology
- Cardiovascular Conditions and Treatments
- Cardiac electrophysiology and arrhythmias
- Radiation Dose and Imaging
- Adipose Tissue and Metabolism
- Neuroscience of respiration and sleep
- Physiological and biochemical adaptations
- Coronary Artery Anomalies
- Primate Behavior and Ecology
- Cardiac Imaging and Diagnostics
- Animal Behavior and Welfare Studies
- Respiratory Support and Mechanisms
- Restraint-Related Deaths
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Effects of Exercise
- Heart Rate Variability and Autonomic Control
- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- Educational Leadership and Innovation
Beaumont Hospital, Royal Oak
2005-2024
Corewell Health
2024
Oakland University
2016-2023
Beaumont Health
2016-2023
Pioneer (United States)
2023
Loma Linda University
2022
Heart Rhythm Society
2020
University of Florida
2020
University of Georgia
2020
Georgia College & State University
2020
To investigate the relationship between daily dose of synthetic opioid methadone and corrected QT (QTc) interval in a series methadone-treated patients who developed torsade de pointes.Retrospective case analysis.Outpatient pain management center maintenance treatment programs.Seventeen pointes while receiving very high doses methadone.The QTc intervals were calculated for each patient. The was assessed adjusted clinical characteristics that may have independently prolonged cardiac...
Background— Device implant pocket hematoma is a recognized complication after permanent pacemaker (PM) and implantable cardioverter-defibrillator (ICD) implantation. Pocket associated with local discomfort, an increased risk of infection, may require surgical intervention or lead to lengthier hospital stays. The purpose the study was identify clinical factors formation PM ICD device Methods Results— subjects this prospective observational were 935 consecutive patients at Beaumont Hospital...
A total of 163 echocardiographic studies on western lowland gorillas (Gorilla gorilla gorilla) were submitted for evaluation; 140 from 99 animals suitable analysis. Of these, 81 (42 35 males ranging in age 11-41+ yr and 39 31 females yr) are reported here. Three 3 56 30 excluded this report due to cardiac abnormalities. Cardiac parameters measured aortic root (Ao Rt) diameter left atrial (L atrium) size. Left ventricular (LV) measurements included internal systole (LVID(s)) diastole...
Limited data exists for types of venous closure and its associated complications in patients after atrial fibrillation (AF) catheter ablation. We evaluated the subcutaneous figure-of-eight (FO8) achieving hemostasis AF ablation compared to manual pressure.284 consecutive that underwent by two operators were included. All received continuous therapeutic warfarin or interrupted novel oral anticoagulants (NOAC) heparin (ACT300-400 s) without reversal. Patients divided into groups: 1) sheaths...
Background: Pulmonary embolism (PE) is frequently evaluated in acute care settings.Despite this, the clinical diagnosis of PE difficult.Results ventilationperfusion (V/Q) scans may be inconclusive, and pulmonary angiograms (PAGs) are cumbersome, involve risk, often unavailable.Using PAG as standard criterion, we relationship between PE, V/Q scans, semiquantitative latex agglutination (LA) Ddimer levels.Methods: Ninety-eight patients who underwent scanning for suspected were enrolled; based...
Preprocedure systemic antibiotic prophylaxis reduces infections in patients undergoing cardiac implantable electronic devices (CIEDs) implantations. Whether pocket irrigation with solution offers any advantage over saline CIED implantation is unknown.Records from 327 consecutive who underwent by three operators February 2011 to January 2014 were reviewed. From 2012, the was used for irrigation; 2012 2014, used. All received preprocedural IV antibiotics. Baseline demographics, comorbidities,...
Until the majority of great ape population is trained for conscious cardiac evaluations, most individuals will require general anesthesia to perform echocardiograms. Within veterinary community, concern exists that certain anesthetic protocols may exacerbate or artificially induce signs disease. Because potential cardiovascular effects, medetomidine has generally been used cautiously in patients with The combination ketamine and frequently by many institutions because its reversibility. To...
Cardiac disease is a major cause of morbidity and mortality for adult gorillas. Previous research indicates sex-based difference with predominantly males demonstrating evidence left ventricular hypertrophy. To evaluate these findings, we analyzed serum markers cardiac measures in large sample The study included 44 male 25 female gorillas housed at American Association Zoo Aquariums (AZA)-accredited zoos. Serum samples were collected from fasted during routine veterinary health exams to...
Cardiovascular disease (CVD) has been identified as a major cause of mortality in all four great ape taxa zoologic institutions. In an effort to better understand and treat CVD captive apes, program called the Great Ape Heart Project (GAHP), based at Zoo Atlanta, collects maintains database echocardiograms other relevant medical information relating cardiac health status apes. Cardiac assessments have become standard practice among North American zoos that house apes are recommended by...
Abstract Assessing and treating cardiovascular disease (or heart disease) is a growing concern for institutions housing great apes, as it major cause of mortality in all four taxa managed human care. As part proactive monitoring plan, zoological managers veterinarians often elect to perform electrocardiograms (ECGs) on their ape populations. ECGs noninvasively evaluate cardiac electrical activity, are thereby capable providing information regarding function. This signature transcribed visual...
Anterior-posterior electrode placement is preferred in electrical cardioversion of atrial fibrillation. However, the optimal anterior-posterior position relation to heart not studied.
Cardiovascular disease is a leading cause of death in zoo-housed great apes, accounting for 41% adult gorilla North American zoological institutions. Obtaining timely and accurate diagnosis cardiovascular gorillas challenging, relying on echocardiography which generally requires anesthetic medications that may confound findings can severe side effects cardiovascularly compromised animals. The measurement brain natriuretic peptide (BNP) has emerged as modality interest the diagnosis,...
Humans have a larger energy budget than great apes, allowing the combination of metabolically expensive traits that define our life history. This is ultimately related to cardiac output, product blood pumped from ventricle and number heart beats per minute, measure available for whole organism physiological activity. To show relationship between output expenditure in hominid evolution, we study surrogate aortic root diameter, humans apes. When compared gorillas chimpanzees, present an...
A 22-yr-old, 86-kg, morbidly obese female orangutan (Pongo pygmaeus abelii) was immobilized and transported to the Denver Zoological Gardens hospital for a routine physical examination. Immediately after arriving at hospital, cyanosis apparent inadequate ventilatory efforts were noted. Clinically significant hypoxia occurred despite attempts ventilate through face mask, place an endotracheal tube began. large volume of pink-tinged frothy fluid flowed from trachea when laryngoscope inserted...
Inherited arrhythmia syndromes are a known, albeit rare, cause of sudden cardiac arrest which may present with characteristic electrocardiogram changes in patients structurally normal heart. There variety distinct arrhythmogenic that arise from mutations voltage gated sodium channels, resulting either gain or loss function. We describe patient primary inherited syndrome presented as arrest. Further workup revealed her was due to combination Brugada and Long QT3 secondary deleterious mutation...
Abstract Cardiovascular disease is the leading cause of morbidity and mortality in zoologically managed adult great apes, accounting for 29%−77% deaths North American population depending on species. In an effort to better understand underlying causes heart disease, implantable loop recorders (ILRs) have been used some cases monitor apes with suspected or known arrhythmia. This a 10‐year review Great Ape Heart Project's experience implanting 21 ILRs 7 gorillas ( Gorilla gorilla ; 9 total ILR...