A5084386880- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diabetes Management and Research
- Connective tissue disorders research
- Diabetes Treatment and Management
- Hormonal Regulation and Hypertension
- Cardiovascular Function and Risk Factors
- Bone and Dental Protein Studies
- Gynecological conditions and treatments
- Genetics and Neurodevelopmental Disorders
- Health and Lifestyle Studies
- Diet and metabolism studies
- Autoimmune and Inflammatory Disorders Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Macrophage Migration Inhibitory Factor
- Uterine Myomas and Treatments
- Hormonal and reproductive studies
- Protease and Inhibitor Mechanisms
- Reproductive System and Pregnancy
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Vitamin K Research Studies
- Growth Hormone and Insulin-like Growth Factors
- Eosinophilic Disorders and Syndromes
- Inflammatory Myopathies and Dermatomyositis
- Ovarian function and disorders
Izmir University
2024
Ege University
2014-2024
Bakırçay Üniversitesi
2023-2024
Manisa Celal Bayar University
2024
İstanbul Eğitim ve Araştırma Hastanesi
2024
The current Coronavirus disease-2019 (COVID-19) pandemic has forced health care teams to look for alternative approaches manage a great number of children with diabetes, not only in rural but also urban locations.The aim was assess the provision information about follow-up new-onset pediatric type 1 diabetes (T1D) patients, and investigate integration telemedicine into routine clinical long term.The changes coefficient variation (CV), standard deviation percentages time range (TIR), below...
Osteogenesis imperfecta (OI) is a group of phenotypically and genetically heterogeneous connective tissue disorders that share similar skeletal anomalies causing bone fragility deformation. This study aimed to investigate the molecular genetic etiology determine relationship between genotype phenotype in OI patients with whole exome sequencing (WES).
ABS tRACt
Glycated hemoglobin (HbA1c) has proven to be indicative in the development of microvascular complications. In this study, contribution HbA1c variability complications was evaluated.Twenty-one cases with type 1 diabetes mellitus (T1DM) who developed and 39 without complications, that were similar terms gender, age diagnosis, insulin treatment, doses (U/kg), mean levels included.Mean T1DM diagnosis 5.87 ± 3.93 years complication group 4.63 3.33 control group. Nephropathy detected 17 cases,...
Aim: Premature adrenarche (PA) has been associated with metabolic and polycystic ovary syndrome (PCOS) and, thus, an increased risk for type 2 diabetes cardiovascular diseases in later life.Mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR), platelet/ lymphocyte (PLR) are parameters used to show inflammation.This study planned evaluate systemic inflammation children PA using MPV, NLR, PLR. Materials Methods:The included 40 female patients diagnosed healthy individuals as a control...
Osteogenesis imperfecta (OI) consists of a group phenotypically and genetically heterogeneous connective tissue disorders that share similar skeletal anomalies causing bone fragility deformation. The aim was to investigate the molecular genetic etiology determine relationship between genotype phenotype in OI patients using targeted next-generation sequencing (NGS).
Polycystic ovary syndrome (PCOS) is a common often observed during adolescence, characterized by ovulatory dysfunction and hyperandrogenism. It determined that, when female fetuses are exposed to high levels of androgens, it increases their likelihood developing PCOS in later ages. The 2D:4D digit ratio, which measures the length index finger compared ring finger, precise anatomical indicator degree prenatal androgen exposure. Higher ratios individuals have been associated with outcomes...
Anormal uterin kanama (AUK), uterus korpusundan süre, miktar, sıklık ve/veya düzen açısından anormal olan olarak tanımlanır. Adölesan dönemde en sık karşılaşılan jinekoendokrinolojik problemdir. Çalışmamızda AUK 40 adölesanın verileri retrospektif incelendi. Hemoglobin 10-12 gr/dL hafif AUK; hemoglobin 8-9,9 orta <8 ağır sınıflandırıldı. Olguların yaş ortalaması 14,38±2,1 (11-17,8) yıldı. ortanca menstrual siklus aralığı 25 (10-45) gün, süresi 10 (4-35) ortalama ped sayısı 6,2...
How does overweight affect the choroid in children? ABSTRACT Objective: To compare choroidal thickness (CT) and vascular index (CVI) of obese children with those normal weight. Materials Methods: Forty-four 35 weight were included study. After a complete ophthalmological examination participants, macula images taken optical coherence tomography enhanced depth imaging mode. The fovea’s central macular thickness, subfoveal, 1000-µm nasal, temporal CT measured. Total area (TCA), luminal (LA),...
Activating variants of the ABCC8 gene cause neonatal diabetes or maturity-onset young (MODY). We report three cases MODY type 12 caused by in encoding sulphonylurea receptor 1, and experience switching from insulin therapy to therapy.We describe a 12.5-year-old girl with permanent mellitus, two mellitus gene. Two these were successfully switched subcutaneous oral glibenclamide, marked improvement glycemic control. In case, glibenclamide dose was progressively increased achieve full (2...
Background and Aims. The optimal basal bolus insulin distribution in type 1 diabetes (T1D) is still controversial. Herein, we aimed to determine the variability of total daily dose according treatment modality technologies from Better Control Pediatric Adolescent Diabetes: Working Create Centers Reference (SWEET) registry. Methods. study cohort was generated by using SWEET database. Patients with T1D for at least 2 years, aged between 2.5 18 one clinic visit June 2010 2021, were included...
Abstract Objectives This study aimed to determine the effects of continuous subcutaneous insulin infusion (CSII) treatment on anthropometric measurements, mean HbA1c, and dosage in patients diagnosed under 5 years age compare with multiple-dose injection therapy (MDI). Methods Children type 1 diabetes mellitus, <5 since 2000 their 19-year follow-up were evaluated retrospectively. Weight, height, body mass index (BMI), blood pressure, HbA1c values recorded for each visit. Results Hundred...
ABS TRACTAim: Congenital hypothyroidism (CH) is one of the most common endocrinological problems in neonatal period.CH, which occurs 1:3,000-4,000 births, a preventable cause mental retardation.In literature, CH dysgenesis thyroid gland, followed by dyshormonogenesis.We aimed to determine prevalence permanent (P-CH) and transient (T-CH) cases up with diagnosis identify prediction method for persistency. Materials Methods:We retrospectively analyzed medical records 105 children CH.TSH levels...
Objective: A contrary relationship between body mass index (BMI) and growth hormone (GH) secretion has been demonstrated in adults. BMI-specific cutoff levels are suggested for identifying deficiency (GHD) adulthood. However, specific values BMI stimulation test responses the childhood age group not certain. In this research, our purpose was to investigate GH peak response children who underwent GHST with a pre-diagnosis of GHD. Material Methods: This retrospective study stimulative testing...
Osteogenesis imperfecta (OI) is a disease caused by defective collagen synthesis. Collagen type 1 found in many structures the cardiovascular system. Endothelial dysfunction, which develops prior to emergence of structural and clinical signs atherosclerosis, believed play key role atherogenesis. dysfunction may be detected presymptomatically non-invasive radiologic methods, such as flow-mediated dilatation (FMD) carotid intima-media thickness (CIMT). These modalities provide early indicators...
Abstract Objectives Familial transmission is observed in approximately 10% of cases with type 1 diabetes mellitus (T1DM). The most important gene determining susceptibility the human leukocyte antigen complex (HLA) located on chromosome 6. More than 50 susceptible loci are associated T1DM have been identified genes other HLA. In this study, it was aimed to investigate molecular genetic etiology by whole-exome sequence (WES) analysis familial no or weakly detected HLA tissue susceptibility....