A5006614308- Cervical Cancer and HPV Research
- AI in cancer detection
- Endometrial and Cervical Cancer Treatments
- Molecular Biology Techniques and Applications
- Global Health Care Issues
- Uterine Myomas and Treatments
- Global Cancer Incidence and Screening
- Medical Imaging and Analysis
- Hepatitis B Virus Studies
- Radiomics and Machine Learning in Medical Imaging
- Digital Imaging for Blood Diseases
- Thyroid and Parathyroid Surgery
- Urinary Tract Infections Management
- Colorectal Cancer Screening and Detection
- Healthcare Systems and Reforms
- Reproductive System and Pregnancy
- Cancer Risks and Factors
- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Pharmaceutical Economics and Policy
- Gestational Trophoblastic Disease Studies
- Pregnancy and Medication Impact
- Urinary Bladder and Prostate Research
- Consumer Market Behavior and Pricing
- Urologic and reproductive health conditions
Obafemi Awolowo University
2012-2025
Adekunle Ajasin University
2021-2025
Ekiti State University
2021-2025
Obafemi Awolowo University Teaching Hospitals Complex
2020-2024
Accelerated cervical cancer control will require widespread human papillomavirus (HPV) vaccination and screening. For screening, sensitive HPV testing with an option of self-collection is increasingly desirable. typing predicts risk precancer/cancer, which could be useful in management, but most current assays are expensive and/or complicated. An existing 15-type isothermal amplification assay (AmpFire, Atila Biosystems, USA) was redesigned as a 13-type (ScreenFire) for public health use....
Abstract Background Accelerated global control of cervical cancer would require primary prevention with human papillomavirus (HPV) vaccination in addition to novel screening program strategies that are simple, inexpensive, and effective. We present the feasibility outcome a community-based HPV self-sampled program. Methods In Ile Ife, Nigeria, 9406 women aged 30–49 years collected vaginal self-samples, which were tested for local study laboratory using Hybrid Capture-2 (HC2) (Qiagen)....
Cervical cancer is a disease of significant concern affecting women's health worldwide. Early detection and treatment at the precancerous stage can help reduce mortality. High-grade cervical abnormalities precancer are confirmed using microscopic analysis histopathology. However, manual biopsy slides time-consuming, needs expert pathologists, suffers from reader variability errors. Prior work in literature has suggested automated image algorithms for analyzing histopathology images captured...
The HPV-Automated Visual Evaluation (PAVE) Consortium is validating a cervical screening strategy enabling accurate in resource-limited settings. A rapid, low-cost HPV assay permits sensitive testing of self-collected vaginal specimens; HPV-negative women are reassured. Triage positives combines genotyping (four groups order cancer risk) and visual inspection assisted by automated evaluation (AVE) that classifies appearance as severe, indeterminate, or normal. Together, the combination...
Hypertensive disorders in pregnancy (HDP) are leading causes of pregnancy-related morbidity and mortality. International guidelines have recommended the use intravenous hydralazine or Labetalol control severe HDP. Oral Nifedipine not been permitted as first-line managing HDP even low-resource settings where skill for access is readily available. This study aimed to determine compare efficacy oral versus retard achieving adequate blood pressure (BP) among pregnant women with Hypertension at...
Cervical cancer is the fourth most common among women and still one of major causes women's death around world. Early screening high grade Intraepithelial Neoplasia (CIN), precursors to cervical cancer, vital efforts aimed at improving survival rate eventually eliminating cancer. Visual Inspection with Acetic acid (VIA) an assessment method which can inspect cervix potentially detect lesions caused by human papillomavirus (HPV), a cause VIA has potential be effective in low resource settings...
Abstract Aim This study was undertaken to determine the prevalence of post‐partum urinary retention after vaginal delivery and examine associated risk factors. Material Methods a prospective observational carried out over 2‐month period at major university teaching hospital in southwestern N igeria. Results Prevalence 29.4%. The majority (93.3%) women had covert while 6.7% overt retention. From bivariate analysis, episiotomy, reduced voiding desire primiparity were factors for (66.6% vs...
Human papillomavirus (HPV) genotype predicts cervical cancer risk, and genotyping could help guide the management of HPV positives as part screening. An isothermal amplification extended test (ScreenFire RS assay) can assay up to 96 samples/controls in 1 hour plus preparation time. A novel format with pre-aliquoted reagents an anti-contamination component (Zebra BioDome) simplify testing process reduce chances post-amplification contamination. We validated Zebra BioDome formulation prior its...
Visual inspection of the cervix with acetic acid (VIA), though error prone, has long been used for screening women and to guide management cervical cancer. The automated visual evaluation (AVE) technique, in which deep learning is predict precancer based on a digital image acetowhitened cervix, demonstrated its promise as low-cost method improve human performance. However, there are several challenges moving AVE beyond proof-of-concept deploying it practical adjunct tool screening. One them...
We study how prices influence the demand for information about a new preventative health technology. conducted field experiment in Nigeria where women were offered opportunity to get screened cervical cancer (at baseline 2/3 of had no knowledge screening). Field staff made house calls give test and also distributed vouchers that randomly varied price screening at point service. find an inverse U-shaped relationship between information: going from zero small positive increased test, but...
Leiomyoma is a smooth muscle benign tumor and it common lesion of the uterus in women reproductive age group with prevalence about 30%. Though uterine fibroid was 6.5% Ile-Ife, 8.5% gynecological admissions Ilesha, Nigeria, vulval leiomyoma very rare often misdiagnosed as Bartholin cyst or other differentials like lipoma, etc. It usually not considered differential masses, but detailed examination use investigative tools, diagnosis can become clearer. This paper presents 2 cases...
Abstract Introduction Human papillomavirus (HPV) genotype predicts cervical cancer risk, and genotyping could help guide management of HPV positives as part screening. An isothermal amplification extended test (ScreenFire RS assay) can assay up to 96 controls/samples in one hour plus preparation time. A novel format with pre-aliquoted reagents an anti-contamination component (Zebra BioDome™) simplify the testing process by substantially reducing time chances post-amplification contamination....