A5017120373- Spectroscopy Techniques in Biomedical and Chemical Research
- Spectroscopy and Chemometric Analyses
- Advanced Fiber Laser Technologies
- Photonic and Optical Devices
- Optical Coherence Tomography Applications
- Laser-Matter Interactions and Applications
- Photonic Crystal and Fiber Optics
- Semiconductor Lasers and Optical Devices
- Spectroscopy and Laser Applications
- Advanced Fluorescence Microscopy Techniques
- Optical Imaging and Spectroscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Optical Network Technologies
- Advanced Fiber Optic Sensors
- Molecular Biology Techniques and Applications
- Thermography and Photoacoustic Techniques
- Photochromic and Fluorescence Chemistry
- Semiconductor Quantum Structures and Devices
- Spectroscopy and Quantum Chemical Studies
- Ocular and Laser Science Research
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Digital Holography and Microscopy
- Nonlinear Optical Materials Studies
- Quantum optics and atomic interactions
Menlo Systems (Germany)
2017-2018
University of Münster
2011-2016
We report on a novel architecture for robust mode-locked femtosecond fiber lasers using nonlinear optical loop mirror with all polarization-maintaining fibers. Due to nonreciprocal phase shift, the can be operated in compact and efficient reflection mode, offering possibility reach high repetition rates easy implementation of tuning elements. In particular, longitudinal mode spacing carrier-envelope offset frequency may controlled order operate laser as an comb. demonstrate pulse generation...
We present a fiber-based optical parametric oscillator (FOPO) pumped by fiber-coupled laser diode. The FOPO consisted of photonic crystal fiber to convert the pump pulses via four-wave mixing and dispersive resonator formed single-mode fiber. Via dispersion filtering, output with bandwidth about 3 nm, temporal duration 8 ps pulse energy up 22 nJ could be generated. By changing repetition frequency diode ±1 kHz, wavelength tuned between 1130 1310 nm within μs, without need change length...
We present the experimental realization of transverse mode conversion in an optical fiber via optically induced long-period grating. The transient gratings are generated by femtosecond laser pulses, exploiting Kerr effect to translate intensity patterns emerging from multimode interference into a spatial refractive index modulation. Since these modulations exist only while pump beam is present, they can be used for switching modes. As localized part grating was written at time and probe...
We present a light source that is well adapted to both narrow- and broadband coherent Raman scattering (CRS) methods. Based on single oscillator, the delivers synchronized pulses via supercontinuum generation narrowband, frequency-tunable four-wave mixing in photonic crystal fiber. Seeding with spectrally filtered part of yields high-pulse energies up 8 nJ possibility scanning bandwidth 2000 cm(-1) 25 ms. All are emitted repetition frequency 1 MHz, which ensures efficient CRS signals while...
We present a purely optical method for background suppression in nonlinear spectroscopy based on linear interferometry. Employing an unbalanced Sagnac interferometer, unprecedented reduction of 17 dB over broad bandwidth 60 THz (2000 cm(-1)) is achieved and its application to femtosecond stimulated Raman scattering loss demonstrated. Apart from raising the signal-to-background ratio measurement intensity spectrum, this interferometric grants access spectral phase resonant χ(3) contribution....
We present in-line interferometric femtosecond stimulated Raman scattering (II-FSRS), a new method to measure the spectral intensity and phase over broad range, potentially in single shot. An analytic model is developed, that excellently reproduces measured spectra. Additionally, performance of II-FSRS directly compared experiments two established techniques, namely induced Kerr-effect spectroscopy.
We present the hyperspectral imaging capabilities of in-line interferometric femtosecond stimulated Raman scattering. The beneficial features this method, namely, improved signal-to-background ratio compared to other applicable broadband scattering methods and simple experimental implementation, allow for a rather fast acquisition three-dimensional raster-scanned data-sets, which is shown PMMA beads lipid droplet in water as demonstration. A subsequent application principle component...
Hyperspectral Stimulated Raman Imaging (SRS) has shown great promise as a label-free chemical imaging technique in biomedical and medical research. We present recent developments SRS integrating compact portable all-fiber laser with balanced detection into an system, aiming to enhance ease-of-use, specificity, reliability acquiring high-speed, multicolor images. The system's adaptability is highlighted by its seamless integration Nikon Eclipse Ti widefield microscope, providing robust...
We present a fully integrated, clinical-compatible SRS imaging device giving access to the complete Raman spectrum during tumor surgeries. Leveraging advantages of compact and robust fiber laser, we have integrated entire microscopy system into clinical cart, facilitating deployment in diverse environments. The laser provides rapid tunability within milliseconds across broad spectral range 700 3300 cm^-1, covering biomedically relevant resonances fingerprint region. For detailed examination...
We present a fully integrated, clinical-compatible SRS imaging device giving access to the complete Raman spectrum during tumor surgeries. Leveraging advantages of compact and robust fiber laser, we have integrated entire microscopy system into clinical cart, facilitating deployment in diverse environments. The laser provides rapid tunability within milliseconds across broad spectral range 700 3300 cm^-1, covering biomedically relevant resonances fingerprint region. For detailed examination...
We present a turn-key portable picosecond fiber laser for efficient quantum dot excitation to generate single photons. The combines mode-hop-free tunability in the regions 770-980 nm and 1150-1500 with high pulse-to-pulse coherence of 98%. A photon purity indistinguishability were demonstrated. An excellent long-term power stability standard deviation less than 0.3% wavelength better 5 pm achieved. enables different semiconductor dots schemes, essential versatile easy-to-use single-photon...
We present a fully integrated, clinical-compatible SRS imaging device giving access to the complete Raman spectrum for histological tissue examination during tumor surgeries.
We present the first proof-of-principle spectroscopic measurements with purely passive dispersive Fourier transformation femtosecond stimulated Raman scattering, which acquisition of full scattering spectrum is possible within microseconds.
We present the experimental realization of transverse mode conversion in an optical fiber via optically induced long-period grating by employing a setup with co-propagating femtosecond write and probe laser pulses.