A5025016335- Forensic Entomology and Diptera Studies
- Restraint-Related Deaths
- Paleopathology and ancient diseases
- Autopsy Techniques and Outcomes
- Forensic Toxicology and Drug Analysis
- Animal testing and alternatives
- Traumatic Ocular and Foreign Body Injuries
- Muscle metabolism and nutrition
- Forensic Anthropology and Bioarchaeology Studies
- Muscle Physiology and Disorders
- Sleep and Work-Related Fatigue
- Plant-based Medicinal Research
- Neuroscience of respiration and sleep
- Non-Invasive Vital Sign Monitoring
- Molecular Biology Techniques and Applications
- Palliative Care and End-of-Life Issues
- Meat and Animal Product Quality
- Forensic and Genetic Research
- Heart Rate Variability and Autonomic Control
- Child Abuse and Related Trauma
- Poisoning and overdose treatments
- Sports injuries and prevention
- Adipose Tissue and Metabolism
- Cannabis and Cannabinoid Research
- Dietary Effects on Health
University of Salzburg
2015-2024
Humboldt-Universität zu Berlin
1996
Edison (Italy)
1967
Forensic estimation of time since death relies on diverse approaches, including measurement and comparison environmental body core temperature analysis insect colonization a dead body. However, most the applied methods have practical limitations or provide insufficient results under certain circumstances. Thus, new that can easily be implemented into forensic routine work are required to deliver more discrete information about postmortem interval (PMI). Following previous skeletal muscle...
The assessment of postmortem degradation skeletal muscle proteins has emerged as a novel approach to estimate the time since death in early mid-postmortem phase (approximately 24 h (hpm) 120 hpm). Current protein-based methods are limited small number proteins, shown undergo proteolysis after death. In this study, we investigated usability target-based and unbiased system-wide protein analysis gain further insights into systemic alterations identify additional markers for interval (PMI)...
Estimating the postmortem interval (PMI) is one of major tasks and a continuous challenge in forensic pathology. It often an exclusion process available methods, which ultimately can lead to unsatisfactory outcome due poor reliability. This problem most acute late PMI, when decomposition proceeds some methods (such as rigor, livor, algor mortis) are no longer applicable. Several such entomology, skeletal muscle protein degradation, study body by application morphological scoring, expected...
Estimation of the postmortem interval in advanced stages is a challenging task. Although there are several approaches available for addressing changes (human) body or its environment (ecologically and/or biochemically), most restricted to specific timeframes individual and environmental conditions. It well known, instance, that buried bodies decompose remarkably different manner than on ground surface. However, data how established methods PMI estimation perform under these conditions...
Abstract The diagnosis of drowning represents a considerable challenge in forensic practice. Typically, it is made by excluding other potential causes death while concurrently identifying key signs drowning. However, cases with prolonged postmortem interval, these characteristic are often absent. To support diagnoses, various supplementary methods have been introduced over time, prominently including qualitative and quantitative diatom tests. One such approach involves comparing...
Awareness of postmortem degradation processes in a human body is fundamental to develop methods for forensic time since death estimation (TDE). Currently, applied approaches are all more or less limited certain phases, have restrictions on behalf circumstances death. Novel techniques, however, rarely exceed basic research phases due various reasons. We report the first application novel method, based decay muscle proteins, recent case murder-suicide, where other TDE failed obtain data....
A most precise determination of the postmortem interval (PMI) is a crucial aspect in forensic casework. Although there are diverse approaches available to date, high heterogeneity cases together with respective postmortal changes often limit validity and sufficiency many methods. Recently, novel approach for time since death estimation by analysis muscle proteins was proposed. It however necessary improve reliability accuracy, especially possible influencing factors on protein degradation....
Abstract Punches without the use of instruments/objects are a common type body violence and as such frequent subject medicolegal analyses. The assessment injuries occurred well potential assault to produce severe harm is based on objective traces (especially documented both parties involved) the—often divergent—descriptions event. Quantitative data regarding punching characteristics that could be used for rare originate mostly in sports science. aim this study was provide physical...
If a dead body is discovered in water, it nearly always raises the question about cause of death, often associated with persistent problem to differentiate between drowning incident and post-mortem immersion. In numerous cases, reliable confirmation death by only possible combination diagnoses obtained from autopsy additional investigations. As latter, use diatoms has been suggested (and debated) since decades. Based on consideration that are present almost every natural waterbody...
Transcatheter aortic valve implantation via transarterial or transapical access is an alternative therapy to treat high-risk patients with severe symptomatic stenosis. Despite growing experience, procedural complications may still occur. We herein report 86-year-old female patient fatal left ventricular rupture after transcatheter Edwards Sapien prosthesis due cardiac amyloidosis. doi: 10.1111/jocs.12305 (J Card Surg 2014;29:623–624)
The analysis of postmortem protein degradation has become large interest for the estimation interval (PMI). Although several techniques have been published in recent years, degradation-based still largely did not exceed basic research stages. Reasons include impractical and complex sampling procedures, as well highly variable protocols literature, making it difficult to compare results. Following a three-step procedure, this study aimed establish an easily replicable standardized procedure...
The diester‐diterpene alkaloid aconitine was quantified by liquid chromatography‐tandem mass spectrometry in post‐mortem specimens of three cases where suicidal ingestion Aconitum napellus L. (‘monkshood’) supposed. In an attempt at rationalization, sample preparation and chromatographic conditions plasma/serum drug analysis routine were utilized. Linearity established from 0.5 to 20 µg L ‐1 using newborn calf serum (NCS) as a surrogate calibration matrix for all types mesaconitine internal...
An accurate estimation of the postmortem interval (PMI) is a central aspect in forensic routine. Recently, novel approach based on analysis muscle protein degradation has been proposed. However, number questions remain to be answered until sensible application this method broad variety cases possible. To evaluate whether altered vivo metabolism interferes with patterns, we conducted comparative study. We developed standardized animal model rats, and collected additional samples from animals...
Abstract The delimitation of the postmortem interval (PMI) is utmost importance in forensic science. It especially difficult to determine PMI advanced decomposition stages and/or when dead bodies are found under uncommon circumstances, such as tents, or other (semi-) enclosed environments. In cases, insect access restricted, morphological assessment body one remaining approaches for PMI. However, this method allows only vague statements/indications about PMI, it required develop new and more...
In recent years, protein decomposition has become of increasing interest for the use in forensic estimation postmortem interval (PMI). Especially skeletal muscle tissue proven to be a prime target tissue, among other reasons, due its large abundance human body. this regard, it is important know whether there are any intra- and intermuscular differences behavior degradation. Thus, samples from different locations within several muscles as well cardiac smooth were collected three autopsy cases...